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ClinicalTrials.gov public records Last synced Oct 19, 2026, 10:05 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 56 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cimetidine Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Cimetidine on the Single-Dose PK of IV- Administered MNTX

NCT01366378
View directory record Official record
Conditions
Healthy Adult Subjects
Interventions
methylnaltrexone
Drug
Lead sponsor
Bausch Health Americas, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Tarrytown, New York
Source: ClinicalTrials.gov public record
Updated Nov 27, 2019 · Synced Oct 19, 2026, 10:05 PM EDT
Completed Phase 2 Interventional Results available

Effect of Oral Cimetidine in the Protoporphyrias

NCT05020184
View directory record Official record
Conditions
Erythropoietic Protoporphyria, X-linked Protoporphyria
Interventions
Cimetidine, Placebo
Drug
Lead sponsor
Amy K. Dickey, M.D.
Other
Eligibility
15 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
Boston, Massachusetts • Winston-Salem, North Carolina • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 19, 2026, 10:05 PM EDT
Completed Not applicable Interventional Results available

PRP vs PRP Plus IGF for Patellar Tendinosis

NCT04350827
View directory record Official record
Conditions
Tendinopathy, Patellar Ligament, Platelet-Rich Plasma
Interventions
Platelet Rich Plasma, Platelet Rich Plasma plus IGF
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Oct 19, 2026, 10:05 PM EDT
Recruiting No phase listed Observational

Zimmer Biomet-RibFix Titan

NCT07485829
View directory record Official record
Conditions
Rib Fracture, Rib Fracture Multiple
Interventions
The RibFix Titan™ device should be used within this arm of the study.
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 19, 2026, 10:05 PM EDT
Completed Not applicable Interventional

A Study to Evaluate the Effect of Cimetidine on CD4 Lymphocyte Counts in HIV Infection

NCT00002092
View directory record Official record
Conditions
HIV Infections
Interventions
Cimetidine
Drug
Lead sponsor
Community Research Initiative of New England
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Brookline, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 19, 2026, 10:05 PM EDT
Completed Phase 1 Interventional

Effect of Cabazitaxel on the QTc Interval in Cancer Patients

NCT01087021
View directory record Official record
Conditions
Neoplasms, Malignant
Interventions
Cabazitaxel (XRP6258)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
8
States / cities
San Diego, California • San Francisco, California • Decatur, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2011 · Synced Oct 19, 2026, 10:05 PM EDT
Recruiting Not applicable Interventional

Persona MC vs PS RCT With ROSA

NCT05391828
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Zimmer-Biomet Persona Medial Congruent (MC) Bearing Design, Zimmer-Biomet Persona Posterior-Stabilized (PS) Bearing Design
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 19, 2026, 10:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

An MRI Investigation of Soft Tissues in Total Hip Arthroplasty

NCT01750606
View directory record Official record
Conditions
Tissue Reaction, Elevated Blood Ion Levels
Interventions
Not listed
Lead sponsor
Zimmer Biomet
Industry
Eligibility
Not listed
Enrollment
397 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
5
States / cities
Flint, Michigan • New Albany, Ohio • Columbia, South Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 19, 2026, 10:05 PM EDT
Completed Phase 4 Interventional Results available

Success Rate of Immediately Loaded Implants With Platform Switched Design Placed in Anterior Part of Mandible and Restored With Fixed Prostheses

NCT00780273
View directory record Official record
Conditions
Edentulism
Interventions
Ankylos Implants, Biomet 3i Prevail Implants
Device
Lead sponsor
Dentsply International
Industry
Eligibility
18 Years to 80 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2014 · Synced Oct 19, 2026, 10:05 PM EDT
Completed Phase 1 Interventional

Phase I Study of PI3(Phosphoinositol 3)-Kinase Inhibitor BAY80-6946 With Paclitaxel in Patients With Advanced Cancer

NCT01411410
View directory record Official record
Conditions
Neoplasms
Interventions
Paclitaxel, Copanlisib (BAY80-6946)
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
3
States / cities
St Louis, Missouri • New York, New York • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 11, 2017 · Synced Oct 19, 2026, 10:05 PM EDT
Enrolling by invitation Not applicable Interventional

Study of Zimmer Biomet Mymobility Application on Reverse Total Shoulder Arthroplasty (RTSA) Outcomes

NCT05789784
View directory record Official record
Conditions
Reverse Total Shoulder Arthroplasty, Physical Therapy
Interventions
mymobility Physical Therapy, Standard Office-based Physical Therapy
Other
Lead sponsor
Campbell Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Palm Beach Gardens, Florida • Columbus, Ohio • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Oct 19, 2026, 10:05 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel

NCT04862585
View directory record Official record
Conditions
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Breast Carcinoma, Prognostic Stage 0 Breast Cancer AJCC v8, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage IA Breast Cancer AJCC v8, Prognostic Stage IB Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8, Prognostic Stage IV Breast Cancer AJCC v8
Interventions
Cimetidine, Dexamethasone, Diphenhydramine, Famotidine, Paclitaxel, Quality-of-Life Assessment, Ranitidine
Drug · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 20, 2025 · Synced Oct 19, 2026, 10:05 PM EDT
Completed No phase listed Observational

Evaluate Effectiveness of the Biomet Lumbar Spinal Fusion System

NCT00758719
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Not listed
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 75 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
4
States / cities
Terre Haute, Indiana • Flint, Michigan • Columbus, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Oct 19, 2026, 10:05 PM EDT
Terminated No phase listed Observational Results available

A Clinical Registry to Collect Patient Outcome Date for the BIOMET® Stimulator Systems

NCT01750840
View directory record Official record
Conditions
Fusion of Spine (Disease), Fractures, Ununited
Interventions
Biomet® EBI Bone Healing System, Biomet Orthopak® Non-Invasive Bone Growth Stimulator System, Biomet SpinalPak® Non-Invasive Spine Fusion Stimulator
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Vineland, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Oct 19, 2026, 10:05 PM EDT
Completed Phase 2 Interventional

Biological Therapy in Treating Patients With Metastatic Cancer

NCT00002733
View directory record Official record
Conditions
Kidney Cancer, Melanoma (Skin), Unspecified Adult Solid Tumor, Protocol Specific
Interventions
aldesleukin, recombinant interferon alfa, therapeutic tumor infiltrating lymphocytes, cimetidine
Biological · Drug
Lead sponsor
Hoag Memorial Hospital Presbyterian
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2000
U.S. locations
1
States / cities
Newport Beach, California
Source: ClinicalTrials.gov public record
Updated May 11, 2011 · Synced Oct 19, 2026, 10:05 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters

NCT05365451
View directory record Official record
Conditions
Interaction, Endogenous Biomarkers
Interventions
MetFORMIN Oral Solution, Cimetidine 400 MG, Furosemide Oral Liquid Product, Probenecid 500 MG
Drug
Lead sponsor
Washington State University
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Aug 8, 2025 · Synced Oct 19, 2026, 10:05 PM EDT
Recruiting No phase listed Observational

Comparison of Artificial Disc Implants in Cervical Disc Arthroplasty

NCT05701059
View directory record Official record
Conditions
Cervical Spondylosis With Myelopathy, Cervical Radiculopathy, Cervical Disc Herniation, Degenerative Disc Disease
Interventions
Cervical arthroplasty, Semi-Constrained Nuvasive Simplify, Unconstrained Biomet Zimmer Mobi-C
Procedure · Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 19, 2026, 10:05 PM EDT
Active, not recruiting No phase listed Observational

Database Retrieval for the Comprehensive Shoulder

NCT03409718
View directory record Official record
Conditions
Osteoarthritis of the Shoulder, Avascular Necrosis, Rheumatoid Arthritis, Prior Failed Revision, Correction of Functional Deformity, Fracture of Proximal End of Humerus, Cuff Tear Arthropathy
Interventions
Biomet Comprehensive Shoulder System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
1
States / cities
Towson, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 19, 2026, 10:05 PM EDT
Recruiting Not applicable Interventional

Hinge vs CCK Implants

NCT07818343
View directory record Official record
Conditions
Revision Arthroplasty, Knee
Interventions
Condylar Constrained knee system. ( NexGen Legacy Condylar Constrained Knee by Zimmer Biomet), Rotating Hinge Knee ( NexGen Rotating Hinge Knee by Zimmer Biomet)
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2037
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Olney, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 19, 2026, 10:05 PM EDT
Recruiting No phase listed Observational

Zimmer ActivBraid Rotator Cuff Repair (RCR) Study

NCT06971497
View directory record Official record
Conditions
Rotator Cuff Repair of the Shoulder
Interventions
ActivBraid™Collagen Co-Braid suture (Zimmer Biomet)
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 19, 2026, 10:05 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Evaluating The Effects Of Cimetidine On The Elimination Of PD 0332334 From The Body

NCT00800280
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
PD 0332334, cimetidine
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 17, 2010 · Synced Oct 19, 2026, 10:05 PM EDT
Completed No phase listed Observational

ExploR™ Modular Radial Head Data Collection

NCT00521846
View directory record Official record
Conditions
Elbow Fracture
Interventions
Biomet Explor Modular Radial Head Replacement
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 19, 2026, 10:05 PM EDT
Recruiting Not applicable Interventional

Zimmer Biomet Shoulder Arthroplasty PMCF

NCT04984291
View directory record Official record
Conditions
Shoulder Fractures, Shoulder Arthritis, Shoulder Osteoarthritis, Shoulder Deformity, Shoulder Injuries, Shoulder Pain
Interventions
Alliance Glenoid, Identity Stem
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
20 Years and older
Enrollment
584 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2033
U.S. locations
12
States / cities
Irvine, California • Golden, Colorado • Chicago, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 19, 2026, 10:05 PM EDT
Terminated Not applicable Interventional Results available

A Multicenter Study to Evaluate Functional Outcome After Knee Replacement

NCT02494544
View directory record Official record
Conditions
Osteoarthritis
Interventions
Off the Shelf Total Knee Replacement, ConforMIS iTotal Knee Replacement
Device
Lead sponsor
Restor3D
Industry
Eligibility
18 Years and older
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
8
States / cities
La Jolla, California • San Diego, California • Parker, Colorado + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 19, 2026, 10:05 PM EDT