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ClinicalTrials.gov public records Last synced Nov 13, 2026, 9:51 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 213 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Clinical guidelines only Clear all

Conditions: Gastrointestinal Cancer
Interventions: Pharmacogenetic test; Device
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years and older
Enrollment: 552 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 3
States / cities: Lancaster, Pennsylvania • Philadelphia, Pennsylvania

Conditions: Heart Failure With Reduced Ejection Fraction, Cognitive Impairment, Mild, Neuroinflammation, Vascular Contributions to Cognitive Impairment and Dementia (VCID)
Interventions: [11C]PS13: [carbon-11]PS13; COX-1 PET radioligand, Sacubitril-Valsartan; Drug
Lead sponsor: Stony Brook University; Other
Eligibility: 50 Years to 75 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: HIV (Human Immunodeficiency Virus), Clinical Decision Support System (CDSS), Antiretroviral Therapy, Highly Active, INDIVIDUALIZED THERAPY, AIDS (Acquired Immune Deficiency Syndrome), Personalized Medicine, Precision Medicine
Interventions: smART (Smart Antiretroviral Therapy Assistant), Traditional Prescribing resources; Other
Lead sponsor: Keck School of Medicine of USC; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2028 – 2031
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Low Back Pain, Veterans Family
Interventions: Pain modulation with physical pain treatment, Telephone delivered self-management counseling for increasing physical activity, Telephone delivered behavioral treatment for participants with high risk for continued disability, Patient preference treatment protocol, Nonpharmacological guideline adherent treatment protocol, Facilitated referrals to existing VA or non-VA pain management resources; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 1,817 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Nicotine Dependence, Transcranial Magnetic Stimulation, Vaping, Smoking Cessation, Smoking (Tobacco) Addiction
Interventions: Varenicline, Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation Sham, Nicotine Cessation Counseling, D-cycloserine; Drug · Device · Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Head Injury Trauma, Traumatic Brain Injury, Mild
Interventions: Clinical pathway 1: Guidelines plus biomarkers, Clinical guidelines only; Diagnostic Test
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 3,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 6
States / cities: Sylmar, California • Torrance, California • Clinton Township, Michigan + 2 more

Conditions: Advanced Melanoma
Interventions: Vusolimogene Oderparepvec, Nivolumab, Nivolumab + Relatlimab, Pembrolizumab, Single-agent chemotherapy; Biological · Drug
Lead sponsor: Replimune, Inc.; Industry
Eligibility: 12 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2031
U.S. locations: 50
States / cities: Gilbert, Arizona • La Jolla, California • Los Angeles, California + 42 more

Conditions: Myelofibrosis, Thrombocytopenia
Interventions: Fostamatinib, Ruxolitinib; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: HPV-Related Carcinoma
Interventions: brief negotiated mobile application; Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: 9 Years to 17 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm, Cancer, Functional Limitation
Interventions: Functional Resistance Training, Stretching, Delayed Functional Resistance Training; Other
Lead sponsor: OHSU Knight Cancer Institute; Other
Eligibility: 65 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Smoking, Smoking Cessation
Interventions: Smartphone-based Financial Incentives, Best Practices; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older · Female only
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 2
States / cities: Anchorage, Alaska • Burlington, Vermont

Conditions: Chronic Brain Injury
Interventions: SPIRIT Club CBI Pathway; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Heart Failure NYHA Class III
Interventions: Cordella™ Pulmonary Artery Sensor System; Device
Lead sponsor: Endotronix, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 738 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 70
States / cities: Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 57 more

Conditions: Tobacco Use Cessation
Interventions: Technical Assistance, training and clinical reminders, TTC+Referral to Community Health Worker; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 80 Years
Enrollment: 4,733 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Acute Coronary Syndrome
Interventions: Darapladib 160 mg, Placebo, Standard Therapy; Drug · Other
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years and older
Enrollment: 13,026 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 290
States / cities: Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 252 more

Conditions: Postoperative Care, Postoperative Complications, Cognition, Nutritional Assessment, Nutritional Intervention
Interventions: Nutritional Shake, Nutritional Instructions Only; Dietary Supplement · Other
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 70 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Obesity
Interventions: Exercise program, Nutrition, WLS; Behavioral · Dietary Supplement · Procedure
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 55 Years to 75 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Surgical Site Infection, Sternal Infection, Cardiac Surgery
Interventions: D-PLEX, Standard of Care; Drug · Other
Lead sponsor: PolyPid Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 2
States / cities: Rochester, Minnesota • Huston, Texas

Conditions: Bacterial Infections, Acute Bacterial Skin and Skin Structure Infection
Interventions: Dalbavancin, Usual Care; Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older
Enrollment: 91 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Heart Failure
Interventions: LLM-GDMT Clinical Decision Support Tool; Device
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 85 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sickle Cell Disease
Interventions: Blood draw, Nasopharyngeal wash; Other
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 1 Year and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Pancreatic Cancer, Pancreatic Diseases, Pancreatitis, Pancreatic Cyst
Interventions: Blood Draw, Tumor Tissue Collection, Cyst Fluid; Diagnostic Test
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2026
U.S. locations: 10
States / cities: Middletown, New Jersey • Montvale, New Jersey • Cold Spring Harbor, New York + 4 more

Conditions: Heart Failure, Systolic, Depression, Cardiovascular Disease
Interventions: Collaborative Care for Heart Failure, Collaborative Care for Depression; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 21 Years and older
Enrollment: 756 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Implementation Science
Interventions: Exposure Based Implementation Strategy (EBIS), Implementation as Usual (IAU); Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Search by objective public record fields.

Implementing Pharmacogenetic Testing in Gastrointestinal Cancers

[11C]PS13 PET Imaging of Neuroinflammation in Heart Failure With Reduced Ejection Fraction

Evaluating a Clinical Decision Support Tool for Antiretroviral Therapy Optimization

Improving Veteran Access to Integrated Management of Back Pain

Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)

The PIONEER Comparative Effectiveness Study - Project 2

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

Fostamatinib as a Single Agent or in Combination With Ruxolitinib for Treatment of Patients With Myelofibrosis With Severe Thrombocytopenia

Integrating Primary & Secondary Interventions for Cervical Cancer Prevention in Primary Care Settings

Phase I Randomized Controlled Trial of Functional Resistance Training in Older Cancer Survivors: The ACES Trial

Remote Incentives for Smoking Cessation Among AN Pregnant Women

SPIRIT Club Chronic Brain Injury Exercise Platform

PROACTIVE-HF IDE Trial Heart Failure NYHA Class III

Implementing Tobacco Use Guidelines in Community Health Centers in Vietnam Public Health System

The Stabilization Of pLaques usIng Darapladib-Thrombolysis In Myocardial Infarction 52 Trial

Nutrition to Support Postoperative Recovery

Surgical vs. Lifestyle in Obese Older Adults

D-PLEX 302: Efficacy and Safety of D-PLEX in the Prevention of Sternal Infection Post Cardiac Surgery

Development of a New Critical Pathway for Treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI)

Targeted Artificial Intelligence Language mOdel Recommendations for Heart Failure (TAILOR-HF)

A New Reagent Assay Examining Natural Parvovirus B19 Infection in Sickle Cell Disease

A Study of Blood Based Biomarkers for Pancreas Adenocarcinoma

Blended Collaborative Care for Heart Failure and Co-Morbid Depression

An Exposure-Based Implementation Strategy to Decrease Clinician Anxiety Around Suicide Prevention