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Showing 1–24 of 164 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Results available

Pragmatic Comparative Effectiveness Trial of Evidence-based, On-demand, Digital Behavioral Treatments for Chronic Pain

NCT04933474
View directory record Official record
Conditions
Chronic Pain
Interventions
painTRAINER®, Skills-Based VR
Behavioral · Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
13 Years and older
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 5, 2026, 11:13 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Neuropsychologic and Electrophysiological Features of Cancer-Related Cognitive Side Effects in Racial and Ethnic Minority Breast Cancer Patients

NCT01473680
View directory record Official record
Conditions
Breast Cancer
Interventions
EEG, Neuropsychological Evaluation, Psychological Questionnaires, Medical Questionnaire
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 61 Years · Female only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
4
States / cities
New York, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 12, 2012 · Synced Sep 5, 2026, 11:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Southwest Hub for American Indian Youth Suicide Prevention Research

NCT03543865
View directory record Official record
Conditions
Suicide, Surveillance, Mental Health, Substance Use, Depressive Symptoms
Interventions
New Hope (NH), Elders Resilience (ER), Case Management (CM)
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
16 Years to 29 Years
Enrollment
304 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Whiteriver, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Sep 5, 2026, 11:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Relationships, Employment, Autonomy, and Life Satisfaction (REALS) Study

NCT04381195
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
REALS Development, REALS Testing
Diagnostic Test
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
1,650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Sep 5, 2026, 11:13 PM EDT
Active, not recruiting Not applicable Interventional

Transcranial Direct Current Stimulation of the Temporal Cortex in Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)

NCT04105530
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia, Transcranial Direct Current Stimulation, Executive Dysfunction
Interventions
Anodal tDCS treatment, Cathodal tDCS treatment, Sham treatment, NIH Toolbox List Sorting Working Memory Test, NIH Toolbox Flanker Inhibitory Control and Attention Test, Grooved Peg Board Test, Buschke Selective Reminding Test
Device · Other
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
8 Years to 215 Months
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced Sep 5, 2026, 11:13 PM EDT
Recruiting Not applicable Interventional

Effects of Accelerated rTMS on Cognitive Function

NCT07547319
View directory record Official record
Conditions
Cognitive Decline, Cognitive Impairment
Interventions
TMS
Device
Lead sponsor
San Francisco Neurology and Sleep Center
Other
Eligibility
50 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 5, 2026, 11:13 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Study of How Proton Beam Radiotherapy (PBRT) Affects Brain Function and Quality of Life in Children and Young Adults Undergoing Treatment for a Brain Tumor

NCT05288439
View directory record Official record
Conditions
Brain Tumor, Metastatic Brain Tumor
Interventions
Resting-state functional connectivity MRI, Neurocognitive battery with quality-of-life assessment
Diagnostic Test · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
6 Years to 25 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Sep 5, 2026, 11:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Investigation of Anatomical Correlates of Speech Discrimination

NCT01781039
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
Hearing Aid fitting
Device
Lead sponsor
Steward St. Elizabeth's Medical Center of Boston, Inc.
Other
Eligibility
18 Years to 100 Years
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Brighton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 5, 2026, 11:13 PM EDT
Not yet recruiting No phase listed Observational

Under-Represented Communities Diagnosed With SCD or MCI Through Tele-Cog

NCT06542458
View directory record Official record
Conditions
Mild Cognitive Impairment, Subjective Cognitive Decline
Interventions
Assessments, Neuroimaging volumetric measures, Biofluid samples
Behavioral · Other
Lead sponsor
Ohio State University
Other
Eligibility
50 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 5, 2026, 11:13 PM EDT
Recruiting Phase 2Phase 3 Interventional

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

NCT07071350
View directory record Official record
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 5, 2026, 11:13 PM EDT
Completed Phase 1 Interventional

Pain Catastrophizing as a Cause for Systemic Inflammation

NCT00823147
View directory record Official record
Conditions
Musculoskeletal Pain
Interventions
Pain Catastrophizing Induction
Behavioral
Lead sponsor
Beth Darnall, PhD
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Sep 5, 2026, 11:13 PM EDT
Recruiting No phase listed Observational

fMRI and Opioid Abstinence

NCT06651333
View directory record Official record
Conditions
Drug Use Disorder, Opioid Dependence, Opioid-Related Disorders, Opioid Use, Opioid Abuse
Interventions
fMRI
Diagnostic Test
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Hartford, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 5, 2026, 11:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Feasibility and Validity of A Novel Computer Based Battery of Assessments in the Elderly

NCT02109419
View directory record Official record
Conditions
Computerized Assessment Feasibility and Validity
Interventions
HHT-G, HHT-D, Geriatric Depression Scale (DGS), MMSE
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
60 Years to 85 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 5, 2019 · Synced Sep 5, 2026, 11:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Flexibility Training for Persistent Pain: Neuroimaging Pilot (COFLEX-i)

NCT03720821
View directory record Official record
Conditions
Chronic Pain, Knee Pain Chronic, Hip Pain Chronic, Back Pain
Interventions
Cognitive Training + fMRI
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 12, 2022 · Synced Sep 5, 2026, 11:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

NEPAL (Neuromodulatory Examination of Pain and Mobility Across the Lifespan)

NCT02488863
View directory record Official record
Conditions
Musculoskeletal Pain, Pain, Chronic
Interventions
MRI Neuroimaging, Quantitative Sensory Testing, Questionnaires, Physical and Cognitive Function Testing
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2024
U.S. locations
4
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Sep 5, 2026, 11:13 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Translational Research Center for TBI and Stress Disorders: Virtual Assessment of Deployment Trauma and Rehabilitation

NCT04723745
View directory record Official record
Conditions
TBI (Traumatic Brain Injury), PTSD
Interventions
V-TRACTS Assessment/Feedback, OPTIONAL Brief Assessment of Thinking, OPTIONAL STEP-Home-Brief, OPTIONAL At-home Exercise Program, OPTIONAL Referral to 12-week STEP-Home, OPTIONAL Clinical Referral
Behavioral
Lead sponsor
VA Boston Healthcare System
Federal
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Sep 5, 2026, 11:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study to Evaluate the Performance Validity and Test-Retest Reliability of a Computer-Administered Cognitive Test Battery in Participants With Major Depressive Disorder (MDD)

NCT03014544
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
Computer- administered test battery, Examiner- administered test battery
Device
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 59 Years
Enrollment
585 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
20
States / cities
Birmingham, Alabama • Anaheim, California • Beverly Hills, California + 17 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 5, 2026, 11:13 PM EDT
Not listed Phase 2 Interventional

Impact of Neuropsychological Evaluation on Epilepsy Treatment

NCT03202082
View directory record Official record
Conditions
Epilepsy
Interventions
Neuropsychological testing
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 27, 2017 · Synced Sep 5, 2026, 11:13 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Brain Structure and Clinical Endpoints in Myotonic Dystrophy Type 2

NCT05854433
View directory record Official record
Conditions
Myotonic Dystrophy Type 2, Myotonic Dystrophy Type 1
Interventions
Non-interventional study
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
30 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 5, 2026, 11:13 PM EDT
Completed Phase 3 Interventional

Efficacy Study Exploring the Effects on Cognition of Sertindole Versus Comparator in Patients With Schizophrenia

NCT00654706
View directory record Official record
Conditions
Schizophrenia, Cognition
Interventions
Sertindole, Quetiapine
Drug
Lead sponsor
H. Lundbeck A/S
Industry
Eligibility
18 Years to 55 Years
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
26
States / cities
Garden Grove, California • National City, California • Pasadena, California + 23 more
Source: ClinicalTrials.gov public record
Updated May 27, 2014 · Synced Sep 5, 2026, 11:13 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Neuroimaging and Neuropsychological Outcomes in Urea Cycle Disorders

NCT02935283
View directory record Official record
Conditions
Urea Cycle Disorders
Interventions
MRI, Behavioral
Procedure · Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
7 Years to 50 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 24, 2024 · Synced Sep 5, 2026, 11:13 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Sport-Related Concussion Recovery in Athletes

NCT06852300
View directory record Official record
Conditions
Concussion Mild, Concussion, Brain
Interventions
Concussion Assessment Battery
Device
Lead sponsor
University of Central Arkansas
Other
Eligibility
18 Years to 26 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2030
U.S. locations
1
States / cities
Conway, Arkansas
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Sep 5, 2026, 11:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural Injury in Adolescents With Concussion

NCT03011983
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Concussion, Mild, Acute Brain Injury
Interventions
MEG, MRI, Neuropsychology assessment
Device · Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years to 17 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 23, 2018 · Synced Sep 5, 2026, 11:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Estrogen and Serotonin on Changing Brain Chemistry

NCT01208324
View directory record Official record
Conditions
Menopause
Interventions
estrogen patch, Amino acids, Placebo Patch, Placebo pills
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
48 Years to 60 Years · Female only
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 1, 2021 · Synced Sep 5, 2026, 11:13 PM EDT