Longitudinal Observational Biomarker Study
Public ClinicalTrials.gov record NCT05204940. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Neurocognitive and Neuroimaging Biomarkers: Predicting Progression Towards Dementia in Patients With Treatment-resistant Late-life Depression (OPTIMUM-Neuro Study)
Study identification
- NCT ID
- NCT05204940
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Lead sponsor
- Centre for Addiction and Mental Health
- Other
- Enrollment
- 506 participants
Conditions and interventions
Conditions
Interventions
- Mechanisms of Late life depression (LLD)-dementia through functional Magnetic Resonance Imaging (fMRI) Behavioral
- Neuropsychological Data Behavioral
- Clinical Scales Behavioral
Behavioral
Eligibility (public fields only)
- Age range
- 60 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 26, 2017
- Primary completion
- Jul 30, 2024
- Completion
- Jul 30, 2024
- Last update posted
- Nov 24, 2024
2017 – 2024
United States locations
- U.S. sites
- 4
- U.S. states
- 4
- U.S. cities
- 4
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA Late-Life Mood, Stress, and Wellness Research Program | Los Angeles | California | 90095 | — |
| Washington University School of Medicine Healthy Mind Lab | St Louis | Missouri | 63110 | — |
| Columbia University Adult and Late Life Depression Clinic | New York | New York | 10032 | — |
| UPMC Late-Life Depression, Evaluation, Prevention, and Treatment Program | Pittsburgh | Pennsylvania | 15213 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05204940, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 24, 2024 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05204940 live on ClinicalTrials.gov.