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ClinicalTrials.gov public records Last synced Oct 30, 2026, 2:57 PM EDT

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Showing 577–600 of 1,813 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cognitive Functioning Clear all
Terminated Phase 2 Interventional Results available

Minocycline for the Treatment of Decreased Mental Function in HIV-Infected Adults

NCT00361257
View directory record Official record
Conditions
HIV Infections
Interventions
Minocycline, Placebo (Tetracycline)
Drug
Lead sponsor
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Network
Eligibility
18 Years to 65 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
16
States / cities
Los Angeles, California • San Diego, California • Denver, Colorado + 13 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2016 · Synced Oct 30, 2026, 2:57 PM EDT
Completed Not applicable Interventional

Neural Markers and Rehabilitation of Executive Functioning in Veterans With Traumatic Brain Injury and Posttraumatic Stress Disorder

NCT01410721
View directory record Official record
Conditions
Traumatic Brain Injury, Posttraumatic Stress Disorder
Interventions
Cognitive Rehabilitation Intervention, Cognitive Rehabilitation Control Intervention
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 13, 2018 · Synced Oct 30, 2026, 2:57 PM EDT
Completed Not applicable Interventional

Strategy Based Technique to Enhance Memory (STEM) for Improving New Learning and Memory (NLM) in Moderate to Severe TBI

NCT04054596
View directory record Official record
Conditions
Traumatic Brain Injury, Cognitive Impairment
Interventions
SME
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Oct 30, 2026, 2:57 PM EDT
Completed Not applicable Interventional

Reducing Help-Seeking Stigma in Young Adults at Elevated Suicide Risk

NCT03646903
View directory record Official record
Conditions
Suicide, Help-Seeking Behavior, Health Behavior
Interventions
Cognitive Bias Modification, Psychoeducation
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 23, 2021 · Synced Oct 30, 2026, 2:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Synaquell on Brain Function of Ice Hockey Players

NCT05498818
View directory record Official record
Conditions
Healthy
Interventions
Synaquell, Placebo
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
13 Years to 19 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 9, 2024 · Synced Oct 30, 2026, 2:57 PM EDT
Completed Not applicable Interventional

Cognitive Rehabilitation of Blast Traumatic Brain Injury (TBI)

NCT01138020
View directory record Official record
Conditions
Traumatic Brain Injury, Cognitive Symptoms
Interventions
Cognitive Intervention, Educational intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 50 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 30, 2026, 2:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Perioperative Audio for Anaesthesia

NCT05291832
View directory record Official record
Conditions
Anesthesia
Interventions
Brain.fm Music, Spectrally-matched Noise
Other
Lead sponsor
Brain.fm, Inc.
Industry
Eligibility
Not listed
Enrollment
329 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Oct 30, 2026, 2:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Functional Outcomes of Stay Strong Stay Healthy Program

NCT02677363
View directory record Official record
Conditions
Quality of Life, Aging, Memory Loss, Cardiovascular Diseases
Interventions
Resistance Exercise
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 3, 2018 · Synced Oct 30, 2026, 2:57 PM EDT
Completed Not applicable Interventional Results available

Home-Based Exercise Program For Recovery After Transcatheter Aortic Valve Replacement

NCT02805309
View directory record Official record
Conditions
Aortic Valve Stenosis
Interventions
Exercise, Cognitive behavioral interventions, Attention control education program
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2021 · Synced Oct 30, 2026, 2:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Amyloid Plaque and Tangle Imaging in Aging and Dementia

NCT00355498
View directory record Official record
Conditions
Memory Disorders, Alzheimer's Disease
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
30 Years and older
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 6, 2020 · Synced Oct 30, 2026, 2:57 PM EDT
Recruiting Not applicable Interventional

Music Therapy for Patients With Alzheimer's Disease

NCT05151562
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer Disease
Interventions
Virtual Music Therapy
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 30, 2026, 2:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Magnetic Resonance Imaging Studies of Motor and Thought Processes

NCT00001361
View directory record Official record
Conditions
Cerebrovascular Disorder, Healthy, Movement Disorder, Nervous System Disease, Spinal Cord Injury
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
610 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 30, 2026, 2:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV

NCT06013579
View directory record Official record
Conditions
HIV Infections, Cognitive Impairment
Interventions
Phase 1 Gym Exercise HIIT, Phase 1 Gym Exercise CME, Phase 2 Home Exercise Coaching Text Messages, Phase 2 Home Exercise Control Text Messages
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
3
States / cities
Birmingham, Alabama • Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Oct 30, 2026, 2:57 PM EDT
Terminated Not applicable Interventional

Hemodialysis-based Interventions to Preserve Cognitive Function

NCT02697942
View directory record Official record
Conditions
Kidney Failure, Chronic
Interventions
cognitive training, exercise training
Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 19, 2018 · Synced Oct 30, 2026, 2:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Whole Foods Supplementation on Cognition

NCT01672359
View directory record Official record
Conditions
Sub-optimal Cognitive Function, Sub-optimal Immune Function
Interventions
Ginkgo Synergy® and Choline, OPC Synergy® and Catalyn, Placebo
Dietary Supplement
Lead sponsor
University of Miami
Other
Eligibility
60 Years and older
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Oct 30, 2026, 2:57 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

NCT05677880
View directory record Official record
Conditions
CADASIL
Interventions
Study Procedures
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
660 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
12
States / cities
Los Angeles, California • San Francisco, California • Denver, Colorado + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 30, 2026, 2:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Acute Pain on Motor Learning in Young vs Older Adults

NCT05471557
View directory record Official record
Conditions
Aging, Pain, Acute, Cognitive Decline, Motor Activity
Interventions
pain delivery
Procedure
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 85 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 30, 2026, 2:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aquatic Exercise for Cognition and Mobility in Older Adults

NCT05501249
View directory record Official record
Conditions
Aging Well, Aging Problems, Cognitive Change, Gait, Unsteady, Mobility Limitation
Interventions
Aquatic Integrated Cognitive Motor Training
Behavioral
Lead sponsor
Emily Dunlap
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 30, 2026, 2:57 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The Effects of Modafinil on Waking Function and on Sleep in Individuals With Primary Insomnia

NCT00124384
View directory record Official record
Conditions
Primary Insomnia
Interventions
CBT-I, modafinil
Behavioral · Drug
Lead sponsor
University of Rochester
Other
Eligibility
25 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 23, 2008 · Synced Oct 30, 2026, 2:57 PM EDT
Completed No phase listed Observational

Learning and Behavior Problems in Children With Chronic Granulomatous Disease and Related Disorders

NCT00005933
View directory record Official record
Conditions
Chediak Higashi Syndrome, Chronic Granulomatous Disease, Job's Syndrome, Leukocyte Disorder
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 30, 2026, 2:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Exploring Neurophysiological Markers of Brain Health

NCT06731452
View directory record Official record
Conditions
Healthy Lifestyle, Health-Related Behavior
Interventions
Strategic Memory Advanced Reasoning Training teaches meta-cognitive strategies for individuals to apply to their daily lives for improved performance
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
22 Years to 100 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 30, 2026, 2:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise Training and Cognitive Function in Kidney Disease

NCT03197038
View directory record Official record
Conditions
Cognitive Function, Preclinical, Chronic Kidney Diseases, Older Adults
Interventions
Partially supervised home-based walking exercise, Control
Behavioral
Lead sponsor
University of Illinois Chicago
Other
Eligibility
60 Years to 80 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 2, 2021 · Synced Oct 30, 2026, 2:57 PM EDT
Completed Not applicable Interventional

Brain Imaging of Psychotherapy for Posttraumatic Stress Disorder (PTSD)

NCT01507948
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Prolonged exposure
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 60 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Palo Alto, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Oct 30, 2026, 2:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Comparison of Magnetic Resonance Imaging in Persons With Heart Failure to Health, Aged Matched Controls

NCT02572648
View directory record Official record
Conditions
Heart Failure
Interventions
Brain Imaging (Neuroimaging), Cognitive Function Assessment
Other
Lead sponsor
Emory University
Other
Eligibility
40 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 21, 2017 · Synced Oct 30, 2026, 2:57 PM EDT