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Showing 1–24 of 49 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Solid Tumors
Interventions
rhEndostatin
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
2 Years to 18 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Boston, Massachusetts
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Release Kinetics of rhBMP-2 Using E-PRF as an Autologous Carrier: An In Vitro Analysis

NCT04670965
Conditions
Bone Loss
Interventions
E-PRF/rhBMP-2 (similar ratios), E-PRF/ACS/rhBMP-2, rhBMP-2/E-PRF, E-PRF only
Biological
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Phase 3 Interventional Accepts healthy volunteers

Nourishing Hair, Skin & Nails Supplement Study (Derm Aid)

NCT04249128
Conditions
Hair Loss, Skin Laxity, Cosmetic Acne, Nails; Soft, Skin Aging
Interventions
Vegetarian Collagen, Keratin, Ceramides, Astaxanthin
Dietary Supplement
Lead sponsor
ProofPilot
Industry
Eligibility
26 Years to 100 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Conditions
Von Willebrand Diseases
Interventions
Use of a postpartum diary and additional blood draws., VWF replacement therapy with Wilate, Tranexamic acid
Other · Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
11
States / cities
Aurora, Colorado • New Haven, Connecticut • Miami, Florida + 8 more
Conditions
Degenerative Disc Disease
Interventions
Intradiscal rhGDF-5, Water for injection
Drug · Other
Lead sponsor
DePuy Spine
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
10
States / cities
Phoenix, Arizona • Santa Monica, California • Durango, Colorado + 7 more
Conditions
Chondral Defect, Articular Cartilage Defect
Interventions
autologous cultured chondrocytes on porcine collagen membrane, Bone Marrow Stimulation
Biological · Procedure
Lead sponsor
Vericel Corporation
Industry
Eligibility
17 Years to 65 Years
Enrollment
309 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
7
States / cities
Sacramento, California • Washington D.C., District of Columbia • Wichita, Kansas + 4 more
Conditions
Gingival Recession
Interventions
enamel matrix derivative, Porcine collagen matrix
Biological · Device
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older
Enrollment
30 participants
Timeline
2019 – 2021
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Phase 2 Interventional Results available

The Fibrin Pad Cardiovascular Study

NCT01681030
Conditions
Cardiovascular Disease
Interventions
EVARREST™, Topical hemostat, Standard of Care
Biological · Other
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
6
States / cities
Indianapolis, Indiana • Kansas City, Missouri • Camden, New Jersey + 2 more
Conditions
Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
Interventions
Serum bovine immunoglobulin, Placebo
Dietary Supplement
Lead sponsor
Monisha Hitesh Shah
Other
Eligibility
6 Years to 30 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Houston, Texas
Completed Phase 1Phase 2 Interventional Results available

Intradiscal rhGDF-5 Phase I/II Clinical Trial

NCT00813813
Conditions
Degenerative Disc Disease
Interventions
Intradiscal rhGDF-5
Drug
Lead sponsor
DePuy Spine
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
8
States / cities
Santa Monica, California • Durango, Colorado • Marietta, Georgia + 5 more
Terminated Not applicable Interventional Results available

Endoscopic Mucosal Resection and Cellular Matrix

NCT03240679
Conditions
Barretts Esophagus With High Grade Dysplasia, Barrett Adenocarcinoma
Interventions
Acell MatriStem® Surgical Matrix
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers

Gelatin, Collagen, Gummy and PINP

NCT03357432
Conditions
Collagen Synthesis
Interventions
gelatin, collagen, gummy dose
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Davis, California
Conditions
Skin Aging
Interventions
Human platelet extract (cosmetic product), Vanicream Gentle Facial Cleanser, EltaMD UV Daily Broad-Spectrum SPF 40, EltaMD PM Therapy Facial Moisturizer, Vanicream Lite Lotion
Biological · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Aging
Interventions
Whey Protein, Collagen Protein, Placebo
Dietary Supplement
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
65 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Galveston, Texas
Completed Phase 1Phase 2 Interventional Results available

A Phase I/II Study of KB103, a Topical HSV1-COL7, on DEB Patients

NCT03536143
Conditions
Dystrophic Epidermolysis Bullosa
Interventions
Topical beremagene geperpavec, Placebo gel
Biological
Lead sponsor
Krystal Biotech, Inc.
Industry
Eligibility
2 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stanford, California
Conditions
Dystrophic Epidermolysis Bullosa, DEB - Dystrophic Epidermolysis Bullosa, Recessive Dystrophic Epidermolysis Bullosa, Dominant Dystrophic Epidermolysis Bullosa
Interventions
KB803, Placebo
Biological · Drug
Lead sponsor
Krystal Biotech, Inc.
Industry
Eligibility
6 Months and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
5
States / cities
Rancho Santa Margarita, California • Coral Gables, Florida • Worcester, Massachusetts + 2 more
Not listed Not applicable Interventional Accepts healthy volunteers

Collagen Protein Versus Placebo on Muscle Recovery

NCT06465407
Conditions
Anthropometrics: Height and Weight, Isometric Standing and Seated Plantarflexion, Calf Muscle Thickness, Achilles Tendon Length and Thickness, Myotonography of the Calf Musculature and Achilles Tendon, Pain Pressure Threshold of the Calf, Pain Scale, Endurance Calf Test, Dietary Analysis
Interventions
Collagen, Maltodextrin
Dietary Supplement
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Orlando, Florida
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

Metabolic Surgery for Atrial Fibrillation Elimination

NCT07027969
Conditions
Atrial Fibrillation, Obesity and Obesity-related Medical Conditions
Interventions
Roux-en-Y Gastric Bypass or Sleeve Gastrectomy, Anti-Obesity Medication (AOM) treatment
Procedure · Drug
Lead sponsor
Ali Aminian
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Anal Fistula, Complex Perianal Fistula
Interventions
RhPDGF-BB
Drug
Lead sponsor
Alexander Hawkins
Other
Eligibility
22 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Terminated Phase 4 Interventional Results available

rhBMP-2 Versus Autograft in Critical Size Tibial Defects

NCT00853489
Conditions
Tibial Fractures
Interventions
recombinant bone morphogenetic protein 2, Autogenous iliac crest bone graft
Device · Procedure
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
13
States / cities
San Francisco, California • Denver, Colorado • Tampa, Florida + 10 more
Conditions
Stenosing Tenosynovitis
Interventions
Amniotic fluid injection, Steroid injection
Biological
Lead sponsor
J&M Shuler
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Athens, Georgia
Conditions
Metopic Craniosynostosis
Interventions
Allogenix Plus
Biological
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Months to 36 Months
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Dystrophic Epidermolysis Bullosa, Recessive Dystrophic Epidermolysis Bullosa, Dominant Dystrophic Epidermolysis Bullosa
Interventions
Topical Beremagene Geperpavec, Placebo
Biological · Other
Lead sponsor
Krystal Biotech, Inc.
Industry
Eligibility
6 Months and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
3
States / cities
Rancho Santa Margarita, California • Stanford, California • Coral Gables, Florida
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
recombinant human endostatin
Biological
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
1
States / cities
Madison, Wisconsin