Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 6, 2026, 4:17 PM EDT

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Showing 1–13 of 13 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Nonterminal Premolar Needing Extraction
Interventions
OsteoGen Plug, BioGide
Device
Lead sponsor
McGuire Institute
Industry
Eligibility
18 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
9
States / cities
Aurora, Colorado • Broomfield, Colorado • Boston, Massachusetts + 6 more
Conditions
Root Canal Therapy
Interventions
Collagen-hydroxyapatite scaffold (Syn-Oss), Collagen Scaffold (Colla-Plug)
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
12 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Dry Eye
Interventions
Dextenza (IDI) (Sustained Release Dexamethasone), (0.4 mg), ProLong™ collagen plugs
Drug · Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Healing Wound
Interventions
Socket preservation
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Socket Preservation With BioHorizon's Striate+ Membrane and MinerOss X Plug

NCT05838651
Conditions
Socket Preservation
Interventions
MinerOss® X Plug, Striate+ Membrane
Device
Lead sponsor
Harvard School of Dental Medicine
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Not yet recruiting Not applicable Interventional

Dynamics of Wound Healing in Patients With Obesity

NCT07756112
Conditions
Wound Healing
Interventions
Collagen Plug (standard of care), Platelet-Rich Fibrin Clot
Procedure
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 70 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Dental Implants, Alveolar Ridge Preservation
Interventions
easy-graft CLASSIC, FDBA with collagen plug
Device
Lead sponsor
Sunstar Americas
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Iowa City, Iowa • Baltimore, Maryland
Conditions
Dry Eye Syndromes, Eye Diseases
Interventions
OTX-DED, Controlled Insertion, Collagen Punctal Plug
Drug
Lead sponsor
Ocular Therapeutix, Inc.
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Anal Fistula
Interventions
Collagen Plug Placement, Seton placement
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
4
States / cities
Los Angeles, California
Completed No phase listed Observational Accepts healthy volunteers

Alveolar Ridge Preservation Procedures

NCT05419778
Conditions
Alveolar Ridge Preservation
Interventions
Osteogen plug®, MInerOss®
Device
Lead sponsor
University of Tennessee
Other
Eligibility
12 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Healing of Extraction Socket
Interventions
Extraction with socket graft
Procedure
Lead sponsor
Boston University
Other
Eligibility
20 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

To Measure Pain Perception Following De-Epithelized Free Gingival Graft Harvesting

NCT03895476
Conditions
Gingival Recession, Palate; Wound
Interventions
palatal wound will be cover with collagen and sutures, palatal wound covered with platelet rich fibrin, palatal wound covered with a collagen sponge and cyanoacrylate, palatal wound covered with a stent
Diagnostic Test
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 70 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Guided Bone Regeneration Around Immediate Implants

NCT01628367
Conditions
Missing Tooth
Interventions
Minimally Traumatic Tooth Extraction, Immediate Implant Placement, Bone Graft Placement, Membrane placement, Collagen plug placement, Medications
Procedure · Device · Biological + 1 more
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 100 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan