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ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:08 AM EDT

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Showing 25–40 of 40 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Community Reinforcement Approach Clear all
Recruiting Not applicable Interventional

Building Social and Structural Connections for the Prevention of Opioid Use Disorder Among Youth Experiencing Homelessness

NCT06311838
View directory record Official record
Conditions
Opioid Use Disorder, Dual Diagnosis, Housing Problems, Mental Disorder in Adolescence, Risk Behavior, Homelessness
Interventions
Motivational Interviewing/Community Reinforcement Approach (MI/CRA), Strengths-Based Outreach and Advocacy (SBOA ), Services as Usual (SAU)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
14 Years to 24 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 29, 2026, 4:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Imaging the Neurobiology of a Behavioral Treatment for Cocaine Dependence

NCT00376558
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Community Reinforcement Approach
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 45 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2016 · Synced Oct 29, 2026, 4:08 AM EDT
Recruiting Not applicable Interventional

Peer-Delivered Behavioral Activation in a CCBHC

NCT07219394
View directory record Official record
Conditions
Major Depressive Disorder, Substance Use Disorders
Interventions
Peer Activate, Peer-delivered non-specific services
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 29, 2026, 4:08 AM EDT
Completed Not applicable Interventional Results available

Efficacy of Computer Delivered Community Reinforcement Approach (CRA) (Bup II)

NCT00929253
View directory record Official record
Conditions
Opiate Addiction
Interventions
Suboxone, CRA, Therapy, CM
Drug · Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated May 27, 2022 · Synced Oct 29, 2026, 4:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hospital Visit as Opportunity for Prevention and Engagement for HIV-Infected Drug Users

NCT01612169
View directory record Official record
Conditions
HIV, AIDS, Substance Abuse, Inpatient
Interventions
Patient Navigation (PN) Group, Patient Navigator Plus Contingency Management (PN+CM) Group
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
801 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
12
States / cities
Birmingham, Alabama • Torrance, California • Miami, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2016 · Synced Oct 29, 2026, 4:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing Effectiveness of the Community Reinforcement Approach and Family Training (CRAFT) With American Indians

NCT03203889
View directory record Official record
Conditions
Substance Use Disorders, Family Members
Interventions
CRAFT-AI, TSF-CSO
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Zuni, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Oct 29, 2026, 4:08 AM EDT
Completed Phase 1Phase 2 Interventional Results available

A Sequenced Behavioral and Medication Intervention for Cocaine Dependence

NCT01986075
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Computer-assisted behavior therapy, Mixed-Amphetamine Salts- Extended Release (MAS-ER), Placebo
Behavioral · Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Oct 29, 2026, 4:08 AM EDT
Completed Phase 3 Interventional

Adolescent Outpatient and Continuing Care Study

NCT01381133
View directory record Official record
Conditions
Substance Abuse, Substance Dependence
Interventions
Chestnut Bloomington Outpatient (CBOP), Motivational Enhancement Therapy/Cognitive Behavior Treatment (MET/CBT 7), Assertive Continuing Care (ACC)
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
12 Years to 18 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Bloomington, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 14, 2013 · Synced Oct 29, 2026, 4:08 AM EDT
Completed Phase 2 Interventional

Behavioral Treatment for Cocaine Dependent Women

NCT00914381
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Behavioral therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 2002
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 31, 2020 · Synced Oct 29, 2026, 4:08 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Training and Implementation of RUBI in Community Mental Health Settings

NCT05742464
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
RUBI
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
Not listed
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Augusta, Maine
Source: ClinicalTrials.gov public record
Updated Feb 24, 2023 · Synced Oct 29, 2026, 4:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Web-delivery of Evidence-based, Psychosocial Treatment for Substance Use Disorders

NCT01104805
View directory record Official record
Conditions
Substance Abuse
Interventions
Therapeutic Education System (TES), Treatment-as-Usual (TAU)
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
507 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
10
States / cities
Danbury, Connecticut • Orlando, Florida • Waipahu, Hawaii + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 29, 2026, 4:08 AM EDT
Completed Phase 2 Interventional

Effective Treatment for Prescription Opioid Abuse

NCT00719095
View directory record Official record
Conditions
Prescription Opioid Dependence
Interventions
buprenorphine taper followed by naltrexone maintenance, Behavioral therapy
Drug · Behavioral
Lead sponsor
University of Vermont Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Apr 15, 2013 · Synced Oct 29, 2026, 4:08 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

A Community-University Approach to Preventing HIV

NCT03938077
View directory record Official record
Conditions
HIV/AIDS and Infections, Drug Abuse, Adolescent Behavior, Drug Usage, Alcohol Use, Mental Health, Tobacco Use, HIV Testing
Interventions
Storytelling 4 Empowerment
Device
Lead sponsor
University of Michigan
Other
Eligibility
16 Years to 21 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
2
States / cities
Ann Arbor, Michigan • Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 10, 2019 · Synced Oct 29, 2026, 4:08 AM EDT
Completed Not applicable Interventional

Leveraging Evidence to Activate Parents

NCT04779229
View directory record Official record
Conditions
Substance Use
Interventions
Parent Activation, Usual Services
Behavioral
Lead sponsor
Oregon Social Learning Center
Other
Eligibility
18 Years to 80 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 29, 2026, 4:08 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Scalable Digital Delivery of Evidence-based Training for Family to Maximize Treatment Admission Rates of Opioid Use Disorder in Loved Ones

NCT05666856
View directory record Official record
Conditions
Community Reinforcement And Family Training, Family Health, Substance-Related Disorders
Interventions
Community Reinforcement And Family Training, We The Village Peer Community Forum
Behavioral
Lead sponsor
We The Village, Inc.
Other
Eligibility
19 Years and older
Enrollment
212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 9, 2024 · Synced Oct 29, 2026, 4:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family-based and Adolescent Residential Drug Treatment

NCT01737632
View directory record Official record
Conditions
Substance Use, Delinquency
Interventions
Multidimensional Family Therapy (MDFT), Adolescent Residential Treatment
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
13 Years to 17 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2010
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Nov 29, 2012 · Synced Oct 29, 2026, 4:08 AM EDT