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Conditions: COVID-19, Vaccine Hesitancy
Interventions: Health Communication, Health Communication + Structural; Behavioral
Lead sponsor: Marc Kiviniemi; Other
Eligibility: 18 Years to 99 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Hazard, Kentucky

Conditions: Bipolar II Disorder
Interventions: Interpersonal and Social Rhythm Therapy (IPSRT-BPII), Seroquel; Behavioral · Drug
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 65 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Healthy
Interventions: Canagliflozin and Metformin Extended Release (XR) Fixed Dose Combination [FDC], Canagliflozin, Metformin Extended Release (XR); Drug
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Heart Failure
Interventions: μCor; Device
Lead sponsor: Zoll Medical Corporation; Industry
Eligibility: 21 Years and older
Enrollment: 265 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 67
States / cities: Sheffield, Alabama • El Cajon, California • Inglewood, California + 60 more

Conditions: Multiple Myeloma
Interventions: BMS-986393, Alnuctamab, Mezigdomide, Iberdomide, Elranatamab, Dexamethasone; Drug
Lead sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company; Industry
Eligibility: 18 Years and older
Enrollment: 187 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 17
States / cities: Birmingham, Alabama • Phoenix, Arizona • Duarte, California + 11 more

Conditions: Prostate Cancer, Health Behavior
Interventions: Prostate Cancer Genius App, US Prevention Taskforce App; Behavioral
Lead sponsor: University of Oklahoma; Other
Eligibility: 55 Years to 69 Years · Male only
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: HIV Infections
Interventions: p24CE1/2 pDNA vaccine, p24CE1/2 pDNA vaccine admixed with full-length p55^gag pDNA vaccine, Full-length p55^gag pDNA vaccine, Placebo; Biological
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 14
States / cities: Birmingham, Alabama • Los Angeles, California • San Francisco, California + 9 more

Conditions: Firearm Violence, Firearm Carriage, Injury Prevention
Interventions: IntERact; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 16 Years to 30 Years
Enrollment: 373 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 3
States / cities: Ann Arbor, Michigan • Flint, Michigan • Saginaw, Michigan

Conditions: Shoulder Pain
Interventions: Propranolol LA (60 mg), Placebo, Shoulder Anatomy Education, Pain Processing Education; Drug · Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 64 Years
Enrollment: 264 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Neisseria Gonorrhoeae Infection
Interventions: Meningococcal Group B Vaccine; Biological
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 25 Years
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Healthy
Interventions: A (canagliflozin and metformin IR individual tablets) / B (canagliflozin/metformin IR FDC tablets), B (canagliflozin/metformin IR FDC tablets / A (canagliflozin and metformin IR individual tablets); Drug
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: 19 Years to 55 Years
Enrollment: 83 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Cancer, Financial Hardship
Interventions: CostCOM (Cost Communication, Financial navigation and counseling), Provision of local and national resources to address financial and social needs, Financial Education, Usual care, Screening for financial and social needs; Behavioral · Other
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 91 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 6
States / cities: Costa Mesa, California • Fountain Valley, California • Irvine, California + 3 more

Conditions: Pediatric Obesity, Sedentary Behavior
Interventions: Garden installation; Other
Lead sponsor: North Carolina State University; Other
Eligibility: 42 Months to 6 Years
Enrollment: 286 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 15
States / cities: Cary, North Carolina • Fuquay-Varina, North Carolina • Knightdale, North Carolina + 2 more

Conditions: HIV/AIDS
Interventions: LinkPositively; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: San Diego, California

Conditions: Postpartum Depression, Pregnancy Related, Environmental Exposure
Interventions: Nature Coach Intervention; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older · Female only
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Nicotine Addiction, Serious Mental Illness
Interventions: Learn to Quit App, Nicotine patch, Nicotine lozenge, Technical Coaching, NCI QuitGuide App; Device · Drug · Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Graft Rejection
Interventions: Rabbit Antithymocyte Globulin (RATG), Rituximab, Bortezomib, Acetaminophen, Antihistamine, Methylprednisolone; Drug
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 2
States / cities: Cincinnati, Ohio

Conditions: Suicide, Suicide, Attempted, Suicidal Ideation, Self Harm
Interventions: MI- Safety Plan, Texts messages, Monitoring, Portal follow-up, Booster call; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 13 Years to 17 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 3
States / cities: Ann Arbor, Michigan • Detroit, Michigan • Cincinnati, Ohio

Conditions: Lymphomas, B-cell Lymphomas
Interventions: JV-213, Leukapheresis; Drug · Procedure
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Clostridium Difficile Infection
Interventions: Placebo, CRS3123; Other · Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 45 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Overland Park, Kansas

Conditions: Gulf War Illness
Interventions: Apnea and Insomnia Relief (AIR), Sleep Education (SE); Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 48 Years to 80 Years
Enrollment: 118 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Gynecologic Cancer
Interventions: Exercise and diet education and instruction; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Psoriasis, Atopic Dermatitis
Interventions: CT-100-004-A, CT-100-004-B; Device
Lead sponsor: Click Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Smokers, Former Smokers
Interventions: lamivudine, rapamycin, Exercise Regimen, Spermidine; Drug · Behavioral · Dietary Supplement
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 60 Years to 85 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: New York, New York

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Addressing COVID-19 Vaccine Hesitancy With Muliti-Level Interventions in Appalachia

Psychotherapy for Bipolar II Depression, Pilot Study, Phase II

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release (XR) With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Benefits of Microcor in Ambulatory Decompensated Heart Failure

A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

Prostate Cancer Genius App Education and Home-based PSA Screening for African American Men

HIV-1-Gag Conserved-Element DNA Vaccine (p24CE) Vaccine Study

Project IntERact V2

Biopsychosocial Influence on Shoulder Pain

Study to Assess Gonorrhoeae Immune Responses Induced by a N. Meningitidis Vaccine

A Study to Assess the Bioequivalence of Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) With Respect to the Individual Components of Canagliflozin and Metformin IR Tablets in Healthy Volunteers

Addressing Financial and Social Needs Among Patients With Cancer

Childcare Outdoor Learning Environments as Active Food Systems

LinkPositively: A Technology-Delivered Peer Navigation and Social Networking Intervention to Improve HIV Care

Nurtured in Nature

Feasibility Trial of a Tailored Smoking Cessation App for People With Serious Mental Illness

Randomized Trial for Mixed Acute Rejection

Adaptive Intervention for Adolescents Following Inpatient Psychiatric Care

A Phase 1 Study of JV-213 Autologous CD79b-targeting Chimeric Antigen Receptor T-cell Therapy in Adults With Relapsed or Refractory B-cell Lymphomas

Phase I Trial to Determine the Safety and Pharmacokinetics of CRS3123.

Pilot Test of Apnea and Insomnia Relief for Veterans With Gulf War Illness

EDITS Pilot Study for Gynecologic Cancer Survivors

An Exploratory Study to Evaluate a Digital Intervention to Disrupt Scratching in Atopic Dermatitis and Psoriasis

A Study of Exercise and Pharmacologic Intervention on Systemic Inflammation