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ClinicalTrials.gov public records Last synced Sep 6, 2026, 1:26 AM EDT

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Showing 25–44 of 20 matching trials from the live ClinicalTrials.gov search.
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Conditions
Temporomandibular Disorder
Interventions
Nerivio treatment
Device
Lead sponsor
Theranica
Industry
Eligibility
12 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Ridgeland, Mississippi • Commack, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Migraine in Adolescents

NCT05654012
Conditions
Migraine
Interventions
MRI, Thermal Stimuli, Pressure stimuli, Pain ratings, Pressure pain thresholds (PPT), Conditioned pain modulation (CPM) efficiency, Hormonal assessment, Migraine-related measures, Neural assessments, Pubertal status
Device · Behavioral · Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
10 Years to 13 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Chronic Migraine
Interventions
Nerivio
Device
Lead sponsor
Theranica
Industry
Eligibility
18 Years to 75 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Lagrangeville, New York
Completed Not applicable Interventional Results available

Evaluation of a Novel Device for Treatment of Migraine Headache

NCT03361423
Conditions
Migraine Without Aura, Migraine With Aura
Interventions
Nerivio Migra-1 active device, Nerivio Migra-1 Sham device
Device
Lead sponsor
Theranica
Industry
Eligibility
18 Years to 75 Years
Enrollment
296 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
7
States / cities
Hartford, Connecticut • Springfield, Missouri • St Louis, Missouri + 4 more
Not listed Not applicable Interventional Accepts healthy volunteers

Neuroimaging Memories of Fear and Safety in the Human Brain

NCT04975009
Conditions
Fear Anxiety, PTSD
Interventions
Fear conditioning
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 50 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Austin, Texas
Recruiting Not applicable Interventional Accepts healthy volunteers

Virtual Contexts for Affective Modulation

NCT06986122
Conditions
Pain Control, Anxiety, Memory
Interventions
Pain Threat Manipulation, Pain Controllability Manipulation
Behavioral
Lead sponsor
Trustees of Dartmouth College
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Hanover, New Hampshire
Conditions
Chemotherapy-induced Peripheral Neuropathy
Interventions
Brief Pain Inventory, Hospital Anxiety and Depression Scale, Neuropathic Pain Symptom Inventory, Diode Laser fiber type Selective Stimulator, Quantitative sensory testing, Conditioned pain modulation efficiency, Spontaneous pain at baseline on 0-10 Numerical Rating Scale (NRS)
Other · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Impact of Aerobic Exercise on Pain Modulation in Healthy Adults

NCT07083219
Conditions
Healthy Adult
Interventions
Aerobic High Intensity Interval Training
Behavioral
Lead sponsor
University of Texas, El Paso
Other
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
El Paso, Texas
Conditions
ACL, Opioid Use, Cryotherapy Effect, Vibration; Exposure, Pain, Postoperative
Interventions
VibraCool mechanical stimulation and neuromodulatory therapeutic device, Cryocompression (Game Ready, Bregs) device, Standard ice packs
Device
Lead sponsor
Columbia University
Other
Eligibility
Not listed
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
New York, New York
Recruiting No phase listed Observational Accepts healthy volunteers

Overlapping Pain Trajectory Study

NCT05752396
Conditions
Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain, Widespread Chronic Pain, Low Back Pain, Healthy Volunteers
Interventions
Conditioned Pain Modulation, Offset Analgesia, Spatial Summation, Temporal Summation
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 19 Years
Enrollment
420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Chronic Pancreatitis, Chronic Pain
Interventions
Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
Diagnostic Test
Lead sponsor
Anna Evans Phillips
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
2
States / cities
Baltimore, Maryland • Pittsburgh, Pennsylvania
Conditions
Knee Osteoarthritis
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
45 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Houston, Texas
Conditions
Migraine in Adolescence
Interventions
Nerivio
Device
Lead sponsor
Theranica
Industry
Eligibility
12 Years to 18 Years
Enrollment
1,629 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bridgewater, New Jersey
Conditions
Chronic Pancreatitis, Chronic Pain
Interventions
Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
Diagnostic Test
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
3
States / cities
Indianapolis, Indiana • Baltimore, Maryland • Pittsburgh, Pennsylvania
Conditions
Migraine, Acute Treatment of Migraine
Interventions
Nerivio
Device
Lead sponsor
Theranica
Industry
Eligibility
8 Years and older
Enrollment
55,261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Bridgewater, New Jersey
Conditions
Migraine
Interventions
Nerivio
Device
Lead sponsor
Theranica
Industry
Eligibility
12 Years to 99 Years
Enrollment
409 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Bridgewater, New Jersey
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural and Psychological Mechanisms of Pain Perception

NCT02446262
Conditions
Pain, Normal Physiology, Healthy Volunteers
Interventions
Instructions, Attention, Thermal Pain, Placebo instructions
Behavioral
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
550 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Chronic Migraine
Interventions
Nerivio
Device
Lead sponsor
Theranica
Industry
Eligibility
18 Years to 75 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
10
States / cities
Newport Beach, California • Santa Monica, California • Hartford, Connecticut + 7 more
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Pancreatic Quantitative Sensory Testing (P-QST)

NCT06996535
Conditions
Chronic Pancreatitis, Chronic Pain, Acute Recurrent Pancreatitis
Interventions
Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
Diagnostic Test
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Cincinnati, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Conditioned Pain Modulation

NCT07234123
Conditions
Healthy Participants
Interventions
conditioned pain modulation, test stimulus
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Seattle, Washington