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Showing 1–24 of 189 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Conservative Clear all
Completed Phase 2 Interventional Results available

Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus Arteriosus

NCT01958320
View directory record Official record
Conditions
Patent Ductus Arteriosus, Surgery, Necrotizing Enterocolitis, Intestinal Perforation
Interventions
pharmacologic treatment of the PDA, no pharmacologic treatment of the PDA, NSAID
Other · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
5 Days to 14 Days
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
13
States / cities
San Diego, California • San Francisco, California • San Jose, California + 9 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Sep 5, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Conservative Treatment of Postprostatectomy Incontinence

NCT00212264
View directory record Official record
Conditions
Urinary Incontinence
Interventions
Behavioral Therapy, Pelvic Floor Electrical Stimulation, Biofeedback, No Treatment
Behavioral · Device · Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
Male only
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2011
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 10, 2016 · Synced Sep 5, 2026, 1:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Treatment of Type II Odontoid Fractures Among the Elderly

NCT00266929
View directory record Official record
Conditions
Neck Injuries, Spinal Injuries
Interventions
surgical, conservative treatment
Procedure
Lead sponsor
AOSpine North America Research Network
Network
Eligibility
64 Years and older
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
14
States / cities
Atlanta, Georgia • Indianapolis, Indiana • Kansas City, Kansas + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2017 · Synced Sep 5, 2026, 1:34 AM EDT
Withdrawn Phase 4 Interventional

Aggressive Versus Conservative Blood Glucose Control in Hospitalized Type 2 Diabetic Patients Using Detemir and Aspart Insulin

NCT00906529
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Levemir (Detemir) and Novolog (Aspart) Insulin
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 15, 2019 · Synced Sep 5, 2026, 1:34 AM EDT
Completed Not applicable Interventional

Liberation From Acute Dialysis

NCT04218370
View directory record Official record
Conditions
Acute Kidney Injury, Kidney; Disease, Acute, Dialysis Related Complication
Interventions
Dialysis
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
4
States / cities
San Francisco, California • St Louis, Missouri • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 5, 2026, 1:34 AM EDT
Completed No phase listed Observational

Pediatric Femur Fracture Registry

NCT03211546
View directory record Official record
Conditions
Femoral Shaft Fracture
Interventions
Conservative (non-surgical) treatment, Surgical treatment
Procedure
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
Up to 16 Years
Enrollment
322 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Sep 5, 2026, 1:34 AM EDT
Completed No phase listed Observational

Pathways Project: Kidney Supportive Care

NCT04125537
View directory record Official record
Conditions
Kidney Diseases, Chronic Kidney Diseases, End Stage Renal Disease, End Stage Renal Disease on Dialysis, Chronic Kidney Disease Requiring Chronic Dialysis
Interventions
IHI Breakthrough Collaborative Model
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
476 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
13
States / cities
Arvada, Colorado • Thornton, Colorado • Westminster, Colorado + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 5, 2026, 1:34 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Effect of Intradetrusor onabotulinumtoxinA Injection Versus Conservative Management on Female Sexual Function in Patients With Bladder Pain Syndrome

NCT06729151
View directory record Official record
Conditions
Bladder Pain Syndrome, Female Sexual Dysfunction
Interventions
Onabotulinum toxin A, Conservative management (dietary and behavioral)
Drug · Behavioral
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 99 Years · Female only
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Sep 5, 2026, 1:34 AM EDT
Completed Not applicable Interventional Results available

Enhancing Conservative Treatment for Urge Incontinence

NCT00223821
View directory record Official record
Conditions
Urinary Incontinence
Interventions
Oxybutynin chloride, extended-release, individually-titrated, Behavior Training
Drug · Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
19 Years and older · Female only
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 18, 2013 · Synced Sep 5, 2026, 1:34 AM EDT
Withdrawn Not applicable Interventional

Randomized CO2 vs Sham Laser Treatment of Provoked Vestibulodynia

NCT03390049
View directory record Official record
Conditions
Vestibulodynia
Interventions
Fractional CO2 Laser Treatment, Sham Laser Treatment
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 9, 2019 · Synced Sep 5, 2026, 1:34 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Conservative Versus Operative - First Time Shoulder Dislocations

NCT05532150
View directory record Official record
Conditions
Shoulder Dislocation
Interventions
Arthroscopic Bankart repair, Physical therapy
Procedure
Lead sponsor
Columbia University
Other
Eligibility
12 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 5, 2026, 1:34 AM EDT
Completed Not applicable Interventional Results available

Imaging Biomarkers of Lymphatic Dysfunction

NCT03760744
View directory record Official record
Conditions
Secondary Lymphedema
Interventions
CDT with Negative Pressure, CDT alone
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
30 Years to 90 Years · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Sep 5, 2026, 1:34 AM EDT
Completed Not applicable Interventional

Effectiveness of Nerve Glide Exercises on Cubital Tunnel Syndrome

NCT03629470
View directory record Official record
Conditions
Cubital Tunnel Syndrome
Interventions
Standard Conservative Treatment, Nerve Gliding Exercises
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 6, 2022 · Synced Sep 5, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Complete Decongestive Therapy With Negative Pressure for Lipedema and Lymphedema Therapy

NCT03634462
View directory record Official record
Conditions
Lipedema, Secondary Lymphedema
Interventions
CDT with graded negative pressure
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
14 Years to 90 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 18, 2020 · Synced Sep 5, 2026, 1:34 AM EDT
Completed Not applicable Interventional

Prospective Randomized Evaluation of an Ultra Conservative Approach to Implantable Defibrillator (ICD) Programming in Patients With a Left Ventricular Assist Device (LVAD).

NCT01977703
View directory record Official record
Conditions
Heart Failure
Interventions
Ultra Conservative ICD Programming, Traditional ICD Programming
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Sep 5, 2026, 1:34 AM EDT
Not listed Phase 3 Interventional

Wallis Mechanical Normalization System for Low Back Pain

NCT00134537
View directory record Official record
Conditions
Low Back Pain
Interventions
Interspinous process and dynamic stabilization, Conservative Care
Device
Lead sponsor
Zimmer Spine
Industry
Eligibility
18 Years to 60 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2012
U.S. locations
17
States / cities
Phoenix, Arizona • Beverly Hills, California • Santa Monica, California + 13 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2011 · Synced Sep 5, 2026, 1:34 AM EDT
Recruiting Not applicable Interventional

DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis

NCT05701917
View directory record Official record
Conditions
Venous Thromboembolism, Deep Venous Thrombosis, Post-Thrombotic Syndrome
Interventions
ClotTriever System, Commercially available/market approved anticoagulation medication including but not limited to: Heparin Sodium, Coumadin, Rivaroxaban, Apixaban, etc.
Device · Drug
Lead sponsor
Inari Medical
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
48
States / cities
Scottsdale, Arizona • Tucson, Arizona • Orange, California + 43 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 5, 2026, 1:34 AM EDT
Completed Phase 3 Interventional

Pediatric Intensive Care Units (ICUs) at Emory-Children's Center Glycemic Control: The PedETrol Trial

NCT01116752
View directory record Official record
Conditions
Pediatric Patient (1m-21y), ICU Admission, Hyperglycemia
Interventions
Active Glycemic Control Strict (80-140mg/dL) vs. Conservative (190-220mg/dL) (with or without Continuous Glucose Monitoring)
Other
Lead sponsor
Indiana University
Other
Eligibility
1 Month to 18 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 30, 2015 · Synced Sep 5, 2026, 1:34 AM EDT
Recruiting Not applicable Interventional

Procedural Framing and Epidural Steroid Injection Outcomes

NCT07498140
View directory record Official record
Conditions
Lumbosacral Radiculopathy
Interventions
Behavioral manipulation of ESI expectations, No behavioral manipulation of ESI expectations, No behavioral manipulation of pharmacotherapy expectations
Behavioral · Other
Lead sponsor
Northwestern University
Other
Eligibility
Not listed
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Chicago, Illinois • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 5, 2026, 1:34 AM EDT
Withdrawn Phase 4 Interventional

The PRIORi-T Trial--Prospective Randomized Investigation of Radiofrequency Targeted Vertebral Augmentation

NCT01480167
View directory record Official record
Conditions
Painful Osteoporotic Vertebral Compression Fractures (VCF)
Interventions
Vertebral Augmentation (STABILIT), Non-operative Management
Device · Other
Lead sponsor
DFINE Inc.
Industry
Eligibility
21 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
6
States / cities
St Louis, Missouri • Lebanon, New Hampshire • Mineola, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced Sep 5, 2026, 1:34 AM EDT
No Longer Available No phase listed Expanded access

Clinical Use of a Magnetic Anal Sphincter Augmentation Device, Trade Name FENIX

NCT02722707
View directory record Official record
Conditions
Fecal Incontinence
Interventions
magnetic anal sphincter augmentation for fecal incontinence
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 30, 2018 · Synced Sep 5, 2026, 1:34 AM EDT
Terminated Phase 4 Interventional

Trial Comparing Three Single Dose Injections for Knee Osteoarthritis

NCT05492851
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Zilretta, Synvisc-One 48 MG in 6 ML Prefilled Syringe, Monovisc 88 MG Per 4 ML Prefilled Syringe
Drug
Lead sponsor
Ohio State University
Other
Eligibility
25 Years to 85 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Columbus, Ohio • Lewis Center, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 9, 2023 · Synced Sep 5, 2026, 1:34 AM EDT
Withdrawn No phase listed Observational

A CCTA Guided Management Strategy Versus a Standard of Care Strategy in Type 2 NSTEMI

NCT06382402
View directory record Official record
Conditions
Myocardial Injury
Interventions
CCTA scan
Radiation
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Sep 5, 2026, 1:34 AM EDT
Completed No phase listed Observational

Thoracolumbar Burst Fractures Study Comparing Surgical Versus Non-surgical Treatment

NCT02827214
View directory record Official record
Conditions
Thoracolumbar Burst Fracture
Interventions
Not listed
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years to 65 Years
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
4
States / cities
San Diego, California • East Syracuse, New York • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Sep 5, 2026, 1:34 AM EDT