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ClinicalTrials.gov public records Last synced Nov 4, 2026, 2:55 AM EST

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Showing 1–24 of 90 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Contrast Echocardiography Clear all

Conditions: Hypertrophic Cardiomyopathy (HCM)
Interventions: myocardial contrast echo; Diagnostic Test
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Hypertrophic Cardiomyopathy
Interventions: Echo and myocardial contrast echocardiography perfusion imaging; Drug
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 19 Years to 80 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Transthoracic Echocardiography, Suspected or Known Structural or Functional Cardiac Abnormality
Interventions: Optison; Drug
Lead sponsor: GE Healthcare; Industry
Eligibility: 9 Years to 17 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 8
States / cities: Phoenix, Arizona • Los Angeles, California • Augusta, Georgia + 5 more

Conditions: Diabetes Mellitus, Heart Failure
Interventions: Tc99m-Maraciclatide; Drug
Lead sponsor: GE Healthcare; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Princeton, New Jersey

Conditions: Cardiac Disease
Interventions: DEFINITY®; Drug
Lead sponsor: Lantheus Medical Imaging; Industry
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 15
States / cities: Tucson, Arizona • Los Angeles, California • Orange, California + 12 more

Conditions: Hypertrophic Cardiomyopathy
Interventions: Noncontrast echocardiography, Contrast Echocardiography, Cardiac magnetic resonance imaging; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Prosthetic Valve Thrombosis
Interventions: Warfarin; Drug
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 3,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2028
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Bronchopulmonary Dysplasia
Interventions: Chest computed tomography (CT) with angiography, Bronchoscopy with bronchoalveolar lavage, Echocardiography, 24 hour esophageal pH ("potential of hydrogen") - multichannel intraluminal impedance (MII) monitoring (reflux testing); Diagnostic Test
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 1 Month to 1 Year
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Right-To-Left Shunt
Interventions: Agitated Saline SoC, ASI-02; Drug
Lead sponsor: Agitated Solutions, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 7
States / cities: Chicago, Illinois • Rochester, Minnesota • Saint Cloud, Minnesota + 3 more

Conditions: Fontan, Right Heart Failure
Interventions: Dual cholate clearance assay, MRI; Device · Radiation
Lead sponsor: HepQuant, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2031
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Hookah Smoking
Interventions: Hookah smoking; Other
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 39 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Non-Compaction Cardiomyopathy
Interventions: Echocardiography, Magnetic resonance imaging (MRI), Computed tomography (CT); Diagnostic Test
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2030
U.S. locations: 3
States / cities: Palo Alto, California • Cleveland, Ohio • Philadelphia, Pennsylvania

Conditions: Cardiac Catheterization, Blood Pressure, Heart Ventricles, Echocardiography, Heart Failure
Interventions: Sonazoid; Drug
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 21 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Heart Disease
Interventions: sulphur hexafluoride lipid-type A microspheres; Drug
Lead sponsor: Bracco Diagnostics, Inc; Industry
Eligibility: 9 Years to 17 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 2
States / cities: St Louis, Missouri • Omaha, Nebraska

Conditions: Chest Pain, Acute Coronary Syndrome
Interventions: Dexmedetomidine, Normal Saline, Intranasal cocaine; Drug
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 115 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Valve Heart Disease
Interventions: MRI, Transthoracic echocardiography exam; Other
Lead sponsor: CryoLife, Inc.; Industry
Eligibility: 18 Years to 89 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Tetralogy of Fallot, Pulmonary Insufficiency
Interventions: Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]; Drug
Lead sponsor: Nemours Children's Clinic; Other
Eligibility: 11 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Wilmington, Delaware

Conditions: STEMI
Interventions: Echocardiogram; Procedure
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 31 Years to 90 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Coronary Artery Disease
Interventions: AI-700 contrast-enhanced echocardiography; Procedure
Lead sponsor: Acusphere; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Watertown, Massachusetts

Conditions: Cardiovascular Disease
Interventions: Not listed
Lead sponsor: Lantheus Medical Imaging; Industry
Eligibility: 18 Years and older
Enrollment: 4,300,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: North Billerica, Massachusetts

Conditions: Breast Cancer
Interventions: Research Cardiac MRI, Biomarkers; Procedure
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older · Female only
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Coronary Artery Disease
Interventions: PB127 for injectable suspension; Drug
Lead sponsor: Point Biomedical; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2003
U.S. locations: 34
States / cities: Phoenix, Arizona • Scottsdale, Arizona • Long Beach, California + 25 more

Conditions: Cardiac Catheterization, Blood Pressure, Heart Ventricles, Echocardiography, Heart Failure
Interventions: Definity; Drug
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 21 Years and older
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Coronary Artery Disease
Interventions: MyoVista device, Computed tomographic coronary angiography, Transthoracic Echocardiography; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: New York, New York

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Perfusion Abnormalities in Hypertrophic Cardiomyopathy

Perfusion Imaging With Myocardial Contrast Echocardiography in HCM

Study to Determine Safety and Dosage of OPTISON in Pediatric Participants

Results of Tc99m-Maraciclatide Scintigraphy in Subjects With Diabetes Mellitus and Heart Failure With Preserved Left Ventricular Ejection Fraction

DEF-315 Better Accuracy in Ejection Fraction (EF) Assessment With DEFINITY

Assessment of Wall Thickness in Hypertrophic Cardiomyopathy

Assessment of TRanscathetEr and Surgical Aortic BiOprosthetic Valve Thrombosis and Its TrEatment With Anticoagulation

Multidimensional Phenotype Classification in Grade 3 Bronchopulmonary Dysplasia

Comparing the Safety and Efficacy of ASI-02 to Agitated Saline for Suspected Right-to-left Shunt

Cholate Clearance in Fontan and Heart Failure

Effects of Hookah Smoking on Blood Flow to the Heart, Muscle and Skin

International Consortium for Multimodality Phenotyping in Adults With Non-compaction

Noninvasive Real-time Intracardiac Pressure Measurements Using Subharmonic Ultrasound

Evaluation of Safety and Efficacy of Lumason in Pediatric Echocardiography

Dexmedetomidine for Reversal of Cocaine's Effects on the Heart

Post-surgical Aortic Hemodynamics After Aortic Valve Replacement

Contrast Enhanced 3D Echocardiographic Quantification of Right Ventricular Volumes in Repaired CHD

Myocardial Contrast Echocardiography for the Assessment of the Infarct Related Artery & Risk Area in Patients w/ NSTEMI.

Phase 3 Safety and Imaging Study of AI-700 in Patients With Suspected Coronary Artery Disease Undergoing Coronary Angiography

Retrospective Safety Study to Compare Mortality in Intensive Care Unite (ICU) Patients Undergoing Echocardiography With or Without DEFINITY®

Biomarkers and Cardiac MRI as Early Indicators of Cardiac Exposure Following Breast Radiotherapy

Familiarization and Safety Study of PB127 Ultrasound Contrast Agent

Noninvasive, Subharmonic Intra-Cardiac Pressure Measurement

Analysis of Surface EKG Signals to Identify Myocardial Dysfunction in Patients at Risk for Coronary Artery Disease