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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Control, low-fat diet Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Age-associated Arterial Dysfunction, Western Diet, and Aerobic Exercise: Role of the Gut Microbiome

NCT03334201
View directory record Official record
Conditions
Aging
Interventions
Western Diet, Non-Western Diet
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 79 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 27, 2021 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Return of First-phase Insulin Secretion in Type 2 Diabetes is Associated With Depletion of Pancreas Lipid

NCT03430310
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Low Glycemic Diet, Control Diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
35 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Sep 28, 2026, 12:16 AM EDT
Terminated Not applicable Interventional

Reducing Insulin, Growth Hormones, and Tumors

NCT03785808
View directory record Official record
Conditions
Diet Modification, Lung Cancer
Interventions
Special Diet Therapy (low-carb), Special Diet Therapy (low-fat), Special Diet Therapy (USDA control)
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 11, 2019 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Yogurt for Prevention of Chronic Inflammation

NCT04149418
View directory record Official record
Conditions
Obesity, Inflammation
Interventions
Yogurt, Control food
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 55 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 15, 2022 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Not applicable Interventional

A Carbohydrate-restricted Diet to Reverse Fatty Liver in Adolescents With Obesity

NCT02787668
View directory record Official record
Conditions
Non-alcoholic Fatty Liver Disease, Childhood Obesity, Insulin Resistance
Interventions
Carbohydrate-restricted diet, Control, low-fat diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
9 Years to 17 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 20, 2022 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Phase 1Phase 2 Interventional

Dietary Intervention With the Modified Atkins Diet in Stroke Rehabilitation

NCT01820663
View directory record Official record
Conditions
Stroke, Ischemic Stroke
Interventions
Modified Atkins Diet, Control diet
Other
Lead sponsor
Burke Rehabilitation Hospital
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Not applicable Interventional Results available

Targeting Obesity to Optimize Health in Cardiac Rehab (TOPCARE)

NCT03423238
View directory record Official record
Conditions
Obesity, Weight Loss, CHD - Coronary Heart Disease
Interventions
Exercise, Health Education, Exercise Compliance, Calorie-Restricted Diet, Behavioral Modification, Weight-Loss Compliance, Dietary Counseling
Other · Behavioral · Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Not applicable Interventional

Understanding the Paradoxical Rise in Blood Glucose in the Context of a Low-carbohydrate Diet

NCT07713316
View directory record Official record
Conditions
Elevated Blood Glucose, Low-carbohydrate Diet
Interventions
Carbohydrate Drink, Fat Drink, Protein Drink
Dietary Supplement
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Weight Reduction and Lifestyle Program in Older Adults

NCT00714506
View directory record Official record
Conditions
Functional Disability, Obesity, Physical Inactivity
Interventions
Diet and physical activity, Physical activity control
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years to 100 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2008
U.S. locations
1
States / cities
McKeesport, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 12, 2016 · Synced Sep 28, 2026, 12:16 AM EDT
Recruiting Not applicable Interventional

Metabolic Impact and Compliance of Controlled, Varying, Mediterranean Diets in Pre-Surgical Prostate Cancer Populations (PROVISIONS)

NCT06487507
View directory record Official record
Conditions
Prostate Cancer
Interventions
Low fat diet, Lower carbohydrate diet
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 80 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Not applicable Interventional

Low Carbohydrate/High Protein Diet to Improve Metabolic Health

NCT03207841
View directory record Official record
Conditions
Spinal Cord, Metabolic Syndrome, Diabetes
Interventions
LC/HP
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 26, 2023 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Not applicable Interventional

Faith-based Approaches in the Treatment of Hypertension (FAITH)

NCT01065831
View directory record Official record
Conditions
Hypertension
Interventions
Motivational interviewing (MINT-TLC)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
373 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 29, 2016 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Phase 1 Interventional

Low Antioxidant Diet in Controlling Cachexia in Patients With Oropharyngeal Cancer Receiving Chemotherapy and Radiation Therapy

NCT00486304
View directory record Official record
Conditions
Cachexia, Head and Neck Cancer, Weight Changes
Interventions
ADD, Placebo
Other
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2012 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Not applicable Interventional Results available

Impact of a Low-Carbohydrate Diet in Pediatric Type 1 Diabetes

NCT03997409
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Dietary Intervention
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
13 Years to 21 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 7, 2023 · Synced Sep 28, 2026, 12:16 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study to Investigate Adipocyte Cell and Lipid Turnover in Obese Adolescents

NCT02395003
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Palmitate Diet
Other
Lead sponsor
Yale University
Other
Eligibility
12 Years to 18 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 25, 2024 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Phase 2 Interventional

The Healthy Life Choices Project in HIV-Positive Patients

NCT00017810
View directory record Official record
Conditions
Diarrhea, HIV Infections
Interventions
Dietary intervention, HIV Self-Care
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2003
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 16, 2021 · Synced Sep 28, 2026, 12:16 AM EDT
Recruiting Not applicable Interventional

Plant-Based Online Weight Loss Through Education and Resources Program and Study

NCT07095543
View directory record Official record
Conditions
Type 2 Diabetes, Overweight and Obese Adults
Interventions
Low-fat, vegan diet
Behavioral
Lead sponsor
Physicians Committee for Responsible Medicine
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessment of Endogenous Oxalate Synthesis

NCT05229952
View directory record Official record
Conditions
Healthy, Kidney Stone, Obesity
Interventions
Low-oxalate controlled diet, Primed, continuous intravenous infusion of 13C2-oxalate
Dietary Supplement · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 12, 2025 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Not applicable Interventional

Global Profiling of Gene and Protein Expression Associated With Coronary Heart Disease Reversal

NCT01805492
View directory record Official record
Conditions
Heart Diseases, Cardiovascular Diseases
Interventions
Dr. Dean Ornish Program for Reversing Heart Disease
Behavioral
Lead sponsor
Windber Research Institute
Other
Eligibility
21 Years and older
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2009
U.S. locations
1
States / cities
Windber, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2013 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Phase 2 Interventional

Low-Fat Diet and/or Flaxseed in Preventing Prostate Cancer

NCT00049309
View directory record Official record
Conditions
Prostate Cancer
Interventions
dietary intervention, flaxseed
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
18 Years to 120 Years · Male only
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
3
States / cities
Ann Arbor, Michigan • Chapel Hill, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Study of BMF-219 in Healthy Adult Subjects and in Adult Subjects With Type 2 Diabetes Mellitus (T2D)

NCT05731544
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
BMF-219
Drug
Lead sponsor
Biomea Fusion Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
443 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
36
States / cities
Canoga Park, California • Fountain Valley, California • La Mesa, California + 28 more
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Not applicable Interventional

Efficacy and Safety of the DASH Diet in Adults With Moderate Chronic Kidney Disease: Pilot Study

NCT02059811
View directory record Official record
Conditions
Hypertension, Chronic Kidney Disease
Interventions
DASH Diet, Control Diet
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 2, 2014 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Not applicable Interventional

Low Energy Availability and Recovery From Resistance Exercise

NCT06623747
View directory record Official record
Conditions
Resistance Exercise
Interventions
Diet
Behavioral
Lead sponsor
Chaise Murphy
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Brookings, South Dakota
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 28, 2026, 12:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Controlled Clinical Study to Determine Novel Health Benefits of Cheese Consumption

NCT02918422
View directory record Official record
Conditions
Metabolic Syndrome X
Interventions
Nutritional and Dietary Manipulation
Other
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Sep 28, 2026, 12:16 AM EDT