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Conditions: Phenylketonuria, Healthy
Interventions: SYNB1618, Placebo; Drug
Lead sponsor: Synlogic; Industry
Eligibility: 18 Years to 64 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 4
States / cities: Boston, Massachusetts • Pittsburgh, Pennsylvania • Nashville, Tennessee + 1 more

Conditions: Obesity, Diabetes Mellitus, Type II, Cardiovascular Disease
Interventions: Normal Sleep/ Normal Meal, Normal Sleep/ Late Meal, Late Sleep/ Normal Meal, Late Sleep/ Late Meal; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 20 Years to 49 Years
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Weight Management, Treatment Of Obesity
Interventions: CE-326,597 100 mg QD, CE-326,597 50 mg QD, CE-326,597 25 mg QD, Placebo, CE-326,597 5mg QD; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 252 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 30
States / cities: Phoenix, Arizona • Fresno, California • National City, California + 23 more

Conditions: Polycystic Ovary Syndrome
Interventions: Metformin; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 21 Years to 40 Years · Female only
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Diabetes Mellitus, Type 2, NASH - Nonalcoholic Steatohepatitis
Interventions: ORMD-0801 (Insulin) capsule 8 mg BD, Placebo; Drug · Other
Lead sponsor: Oramed, Ltd.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Tustin, California

Conditions: Healthy
Interventions: Nephure Oxalate-reducing Enzyme, Placebo; Dietary Supplement · Other
Lead sponsor: Captozyme, Inc.; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Springfield, Missouri

Conditions: Heart Failure
Interventions: Nutritional Support; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 192 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Cognition
Interventions: Ready-To-Eat Cereal; Other
Lead sponsor: General Mills; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 184 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Type 2 Diabetes
Interventions: Insulin glargine/lixisenatide (HOE901/AVE0010), Insulin glargine (HOE901), Metformin (Background Drug); Drug
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years and older
Enrollment: 736 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 108
States / cities: Birmingham, Alabama • Sun City, Arizona • Tempe, Arizona + 91 more

Conditions: Healthy
Interventions: Control, Soluble corn fiber, Resistant starch, Fructooligosaccharide, Inulin; Dietary Supplement
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Saint Paul, Minnesota

Conditions: Type 2 Diabetes
Interventions: Lixisenatide (AVE0010), Placebo, Antidiabetic background therapy; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 70 Years and older
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 14
States / cities: La Jolla, California • Norwalk, California • Miami, Florida + 10 more

Conditions: Healthy Volunteers
Interventions: AMG 378, Placebo; Drug
Lead sponsor: Amgen; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 2
States / cities: Lake Forest, California • Overland Park, Kansas

Conditions: Health Behavior, Diet, Healthy
Interventions: Health Warning Label, Identity Warning Label, Barcode Label; Behavioral · Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 55 Years
Enrollment: 4,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Bipolar Disorder
Interventions: Placebo, Metformin; Drug
Lead sponsor: Cynthia Calkin; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Dyslipidemia, Overweight and Obesity, Nutrition, Healthy
Interventions: CSO-30, CSO-20, Control; Other
Lead sponsor: University of Georgia; Other
Eligibility: 25 Years to 75 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Athens, Georgia

Conditions: Breast Cancer
Interventions: Green tea extract supplement, Placebo; Drug · Other
Lead sponsor: University of Minnesota; Other
Eligibility: 50 Years to 70 Years · Female only
Enrollment: 1,075 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 5
States / cities: Edina, Minnesota • Maple Grove, Minnesota • Minneapolis, Minnesota + 2 more

Conditions: Hypogonadism, Male
Interventions: SOV2012-F1, AndroGel; Drug
Lead sponsor: Marius Pharmaceuticals; Industry
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 314 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 36
States / cities: Birmingham, Alabama • Mobile, Alabama • Tucson, Arizona + 31 more

Conditions: Obesity
Interventions: Almonds 43g/day; Dietary Supplement
Lead sponsor: Purdue University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: West Lafayette, Indiana

Conditions: Sexual Wellness, Women Health
Interventions: Shatavari (Asparagus racemosus) Root Extract, Placebo Capsule; Dietary Supplement · Other
Lead sponsor: SF Research Institute, Inc.; Network
Eligibility: 20 Years to 50 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Diabetes Mellitus, Type 2
Interventions: Canagliflozin 100 mg, Canagliflozin 300 mg, Metformin XR; Drug
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 1,186 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 52
States / cities: Birmingham, Alabama • Phoenix, Arizona • Encinitas, California + 49 more

Conditions: Healthy Participants, Dyslipidemia
Interventions: AZD4954, Placebo; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 136 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 6
States / cities: Glendale, California • Inverness, Florida • Jacksonville, Florida + 3 more

Conditions: Constipation
Interventions: Senna+ docusate, placebo; Drug
Lead sponsor: Hartford Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Hypertriglyceridemia
Interventions: DHA-rich fish oil versus Phospholipid-rich fish oil; Dietary Supplement
Lead sponsor: Arctic Nutrition AS; Industry
Eligibility: 18 Years to 59 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Addison, Illinois

Conditions: Type 2 Diabetes Mellitus
Interventions: PF-04937319 IR MST, PF-04937319 MR 1, PF-04937319 MR 2, PF-04937319 MR 3; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 2
States / cities: High Point, North Carolina • San Antonio, Texas

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Safety and Tolerability of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria

Impact of Sleep and Meal Timing on Food Intake Regulation

A Trial In Diabetic Patients To Assess Effect Of CE-326,597 On Glucose Control And Body Weight

Study of Brain Function in Women With Insulin Resistant Polycystic Ovary Syndrome

A Study to Assess the Safety and Efficacy of Oral Insulin in T2DM Patients With Nonalcoholic Steatohepatitis (NASH)

Evaluation of Nephure™, and the Reduction of Dietary Oxalate, in Healthy Volunteers

Cardiac Recovery Through Dietary Support

Appetite and Cognition Response to a Breakfast Cereal

Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination Versus Insulin Glargine in Patients With Type 2 Diabetes

Satiety Response of Four Dietary Fibers

Efficacy and Safety of Lixisenatide Versus Placebo on Top of Basal Insulin and/or Oral Antidiabetic Treatment in Older Type 2 Diabetic Patients

Single and Multiple Ascending Dose Study of AMG 378 in Healthy Participants

Impacts of Warning Labels on Ultra-Processed Foods

Treating Insulin Resistance as a Strategy to Improve Outcome in Refractory Bipolar Disorder

Intermittent Cottonseed Oil Consumption

Green Tea and Reduction of Breast Cancer Risk

Efficacy and Safety of Oral Testosterone Undecanoate in Hypogonadal Men

Metabolic Effects of Almond in the Longer-term Study

Efficacy and Safety of Shatavari Root Extract in Women's Sexual Wellness

A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control With Diet and Exercise

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels, and Participants With Dyslipidemia

The Use of SennaS for Prevention of Post-operative Constipation After Urogynecologic Surgery

Bioavailability of EPA and DHA From Two Dietary Supplements

Study To Compare Single Dose Of Three Modified Release Formulations Of PF-04937319 With Immediate Release Material-Sparing-Tablet (IR MST) Formulation Previously Studied In Adults With Type 2 Diabetes Mellitus.