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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:08 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1345–1368 of 4,175 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Control comparison Clear all

Conditions: Alzheimer Disease, Cognitive Decline, Aging
Interventions: California Cognitive Assessment Battery; Diagnostic Test
Lead sponsor: Neurobehavioral Systems, Inc.; Industry
Eligibility: 18 Years to 89 Years
Enrollment: 2,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Berkeley, California

Conditions: Skin
Interventions: Lumenato; Dietary Supplement
Lead sponsor: LycoRed Ltd.; Industry
Eligibility: 35 Years to 55 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Fairfield, New Jersey

Conditions: Contraception
Interventions: Estradiol valerate, Dienogest (Natazia, Qlaira, BAY86-5027), Ortho Tri Cyclen Lo; Drug
Lead sponsor: Bayer; Industry
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 409 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 34
States / cities: Independence, Arizona • Phoenix, Arizona • Encinitas, California + 29 more

Conditions: Coronary Artery Disease
Interventions: MICS CABG, Conventional CABG; Procedure
Lead sponsor: Ottawa Heart Institute Research Corporation; Other
Eligibility: 18 Years and older
Enrollment: 176 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2028
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania • La Crosse, Wisconsin

Conditions: Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Interventions: Eplontersen, ALXN2220, Placebo; Drug · Biological · Other
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 326 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 24
States / cities: La Jolla, California • San Francisco, California • Stanford, California + 21 more

Conditions: Health Behavior
Interventions: Emails and letter intervention, Control group; Behavioral
Lead sponsor: Office of Evaluation Sciences; Federal
Eligibility: Not listed
Enrollment: 44,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Diabetes Mellitus Type 2
Interventions: placebo, taspoglutide; Drug
Lead sponsor: Hoffmann-La Roche; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 373 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 10
States / cities: Phoenix, Arizona • Los Angeles, California • Santa Ana, California + 7 more

Conditions: Testicular Neoplasms
Interventions: Questionnaire; Behavioral
Lead sponsor: Lawrence Einhorn; Other
Eligibility: 18 Years to 55 Years · Male only
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Colitis Ulcerative
Interventions: Dupilumab, Placebo; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 27
States / cities: Apple Valley, California • Beverly Hills, California • Oxnard, California + 24 more

Conditions: Exercise, Physical Activity, Healthy Adult, Interoception, Affect and Exertion During and Post-exercise
Interventions: Eyes-Closed Interoceptive Aerobic Exercise, Matched Eyes-Open Treadmill Exercise; Behavioral
Lead sponsor: Old Dominion University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Norfolk, Virginia

Conditions: Endoscopic Ultrasound
Interventions: SuperNO2VA; Device
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 2
States / cities: Indianapolis, Indiana

Conditions: Laparoscopic Adnexal Surgery
Interventions: Normal Saline (0.9% NaCl), Marcaine hydrochloride without epinephrine 0.5%; Other · Drug
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years and older · Female only
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Dermatochalasis of Eyelid, Ptosis, Eyelid, Ectropion, Entropion
Interventions: Brimonidine Topical; Drug
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Gut Permeability, Gut Health
Interventions: human lactoferrin, Placebo; Dietary Supplement
Lead sponsor: Helaina Inc.; Industry
Eligibility: 18 Years to 40 Years
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Addison, Illinois

Conditions: Open Chest Wounds
Interventions: Wound Vacuum-assisted dressing, Control group; Device · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Alpha1-proteinase Inhibitor Deficiency, Emphysema
Interventions: Alpha1-proteinase inhibitor, Placebo; Biological · Other
Lead sponsor: CSL Behring; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 4
States / cities: Denver, Colorado • Miami, Florida • Hershey, Pennsylvania + 1 more

Conditions: Gynecologic Diseases
Interventions: AirSeal trocar, Standard trocar; Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 132 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Urinary Incontinence
Interventions: rPMS device, Pelvic floor muscle training; Device · Procedure
Lead sponsor: BTL Industries Ltd.; Industry
Eligibility: 25 Years to 70 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 4
States / cities: Wellesley, Massachusetts • Somerset, New Jersey • Newtown, Pennsylvania + 1 more

Conditions: Presbyopia
Interventions: Control Lens (comfilcon A), Test Lens (lehfilcon A); Device
Lead sponsor: CooperVision International Limited (CVIL); Industry
Eligibility: 42 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 4
States / cities: Medina, Minnesota • Vestal, New York • Granville, Ohio + 1 more

Conditions: Psychopathology
Interventions: Mom Power, Mom Power Informational Mailing; Behavioral
Lead sponsor: Tulane University; Other
Eligibility: 3 Years and older
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Low Back Pain
Interventions: Oxycodone/Naloxone Controlled-release, Placebo; Drug
Lead sponsor: Purdue Pharma LP; Industry
Eligibility: 18 Years and older
Enrollment: 1,095 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 151
States / cities: Birmingham, Alabama • Haleyville, Alabama • Huntsville, Alabama + 123 more

Conditions: Malignant Head and Neck Neoplasm, Mucositis, Radiation-Induced Disorder
Interventions: Educational Intervention, Gabapentin, Pain Therapy, Quality-of-Life Assessment, Questionnaire Administration, Oxycodone/Acetaminophen, Hydrocodone/Acetaminophen, Fentanyl, Ibuprofen, Magic Mouthwash; Other · Drug
Lead sponsor: Vanderbilt-Ingram Cancer Center; Other
Eligibility: 21 Years and older
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Bulimia Nervosa
Interventions: FBT-BN, SPT; Behavioral
Lead sponsor: University of Chicago; Other
Eligibility: 12 Years to 19 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2006
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: ACL, Opioid Use, Cryotherapy Effect, Vibration; Exposure, Pain, Postoperative
Interventions: VibraCool mechanical stimulation and neuromodulatory therapeutic device, Cryocompression (Game Ready, Bregs) device, Standard ice packs; Device
Lead sponsor: Columbia University; Other
Eligibility: Not listed
Enrollment: 130 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: New York, New York

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Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease

A Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Nutritional Supplement Lumenato and Its Impact on Skin Parameters in Healthy Female Subjects

To Compare SH T00658ID Over Ortho Tri-Cyclen Lo (US/Canada)

The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial

A Study to Evaluate the Efficacy and Safety of Concomitant Use of Eplontersen and ALXN2220 Compared With Eplontersen and Placebo for Adults Participants With ATTR-CM

Using Personalized Letters and Emails to Increase Health Insurance Take-up and Improve Plan Choice Quality

A Study of Taspoglutide Versus Placebo for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Diet and Exercise.

The Platinum Study Comparison Group

A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))

Eyes-Closed Interoceptive Aerobic Exercise Compared With Matched Eyes-Open Treadmill Exercise in Healthy Adults

Comparison of Oxygenation Between Nasal PAP vs Nasal During Propofol-based Sedation for EUS

Pain with Differing Intraperitoneal Washes At the End of Laparoscopic Gynecologic Surgery

Brimonidine for Intraoperative Hemostasis

Effects of Effera Human Lactoferrin at One Dose Compared to Placebo on Gut Permeability

Vacuum-Assisted Dressings (V-AD) in the Management of Open Chest Wounds

Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor Deficiency

AirSeal®Insufflation Trocar/CO2 Absorption Study

rPMS Compared With Pelvic Floor Exercises for Treatment of Urinary Incontinence

Performance Comparison of Two Monthly Replacement Silicone Hydrogel Multifocal Lens Types

Virtual Mom Power With High-Adversity Mothers and Children (MPHAMC)

Efficacy and Safety of Oxycodone/Naloxone Controlled-release Tablets (OXN) Compared to Placebo in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Gabapentin Compared to Standard of Care in Preventing Mucositis in Patients With Stage III-IV Head and Neck Cancer Undergoing Primary or Adjuvant Chemoradiation Therapy

Family Therapy for Adolescent Bulimia Nervosa

VibraCool Device to Reduce Pain and Opioid Use After Anterior Cruciate Ligament Reconstruction (ACLR)