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ClinicalTrials.gov public records Last synced Sep 4, 2026, 4:07 PM EDT

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Showing 1–24 of 278 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Myopia
Interventions
Atropine, MiSight contact lenses
Drug · Device
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
5 Years to 12 Years
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Myopia
Interventions
Sapphire Lens, enfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Berkeley, California
Conditions
Primary Open-angle Glaucoma (POAG) Patient
Interventions
SENSIMED Triggerfish®
Device
Lead sponsor
Sensimed AG
Industry
Eligibility
40 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
New York, New York
Conditions
Unilateral Cataract Extraction, Congenital Cataract
Interventions
OMS302, Phenylephrine HCl
Drug
Lead sponsor
Omeros Corporation
Industry
Eligibility
1 Day to 47 Months
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
11
States / cities
Los Angeles, California • Atlanta, Georgia • Chicago, Illinois + 8 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Assessment of a Customized Free-form Progressive Addition Lens Spectacle

NCT01234207
Conditions
Presbyopia
Interventions
Standard, non-free-form, non-customized PAL spectacles, Individually customized free-form surfaced PAL spectacles
Device
Lead sponsor
University of California, Berkeley
Other
Eligibility
39 Years to 80 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Berkeley, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Approved and Investigational Contact Lenses

NCT03228212
Conditions
Visual Acuity
Interventions
CONTROL, TEST
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 49 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
5
States / cities
Jacksonville, Florida • East Lansing, Michigan • Pickens, South Carolina + 1 more
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Accommodative Responses of Soft Contact Lenses for Myopia Control

NCT03635528
Conditions
Visual Acuity
Interventions
Test Lens 1, Test Lens 2, Test Lens 3, Test Lens 4, Test Lens 5, Control Lens 1, Control Lens 2
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 25 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
Myopia
Interventions
Test lens, Control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
2
States / cities
Berkeley, California • Bloomington, Indiana
Conditions
Presbyopia Condition
Interventions
Test lens, Control lens
Device
Lead sponsor
Bruno Vision Care
Industry
Eligibility
45 Years to 70 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
3
States / cities
Longwood, Florida • Pittsburg, Kansas • Warwick, Rhode Island
Conditions
Cataract Extraction
Interventions
OMS302, OMS302-PE, Vehicle
Drug
Lead sponsor
Omeros Corporation
Industry
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
4
States / cities
Redding, California • Bloomington, Minnesota • Kansas City, Missouri + 1 more
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of The Comfort of Orthokeratology Lenses Fit Using A New Software

NCT05389072
Conditions
Myopia
Interventions
control contact lens
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
6 Years to 35 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
3
States / cities
San Diego, California • Glenview, Illinois • Bellaire, Texas
Conditions
Refractive Errors
Interventions
DT1 Toric contact lenses, AO1DfA contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
2
States / cities
Maitland, Florida • Eden Prairie, Minnesota
Conditions
Presbyopia
Interventions
UNR844, Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
45 Years to 55 Years
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
12
States / cities
Laguna Hills, California • Newport Beach, California • Largo, Florida + 8 more
Conditions
Eye Disorders, Cataract Extraction, Cataract and IOL Surgery, Cataract Surgery Experience, Cataract Surgery, Intraocular Lens
Interventions
LLM-based Education
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Palo Alto, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Astigmatic Contact Lenses

NCT03086447
Conditions
Visual Acuity
Interventions
Investigational Contact Lens, Marketed Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
267 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
17
States / cities
Whittier, California • Jacksonville, Florida • Jacksonville Beach, Florida + 14 more
Terminated Not applicable Interventional Results available

The Effect of Low-Level Laser Stimulation on Hearing Thresholds

NCT01820416
Conditions
Hearing Loss
Interventions
Low-level Laser Therapy, Placebo Comparator: Disabled Laser
Radiation · Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 75 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers

NCT00889252
Conditions
Allergic Conjunctivitis
Interventions
contact lens with ketotifen, contact lens
Device
Lead sponsor
Vistakon Pharmaceuticals
Industry
Eligibility
8 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Presbyopia
Interventions
Control Lens (comfilcon A), Test Lens (lehfilcon A)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
42 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
4
States / cities
Medina, Minnesota • Vestal, New York • Granville, Ohio + 1 more
Conditions
Cataract Senile
Interventions
Cataract Surgery
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
22 Years to 100 Years
Enrollment
284 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
14
States / cities
Beverly Hills, California • Northridge, California • Orange, California + 11 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Performance of Senofilcon A Investigational Lens

NCT05300763
Conditions
Visual Acuity
Interventions
senofilcon A prototype, Dailies Total 1
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
344 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
19
States / cities
San Francisco, California • Jacksonville, Florida • Longwood, Florida + 13 more
Completed No phase listed Interventional Accepts healthy volunteers Results available

Visual Performance of Soft Contact Lenses With Myopia Control Optics

NCT05141448
Conditions
Visual Acuity
Interventions
1-Day Acuvue Moist, EMO-118, EMO-114, MiSight® 1 day
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 17 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Conditions
Cataract
Interventions
MELT-300 sublingual tablet, Midalozam sublingual tablet, Placebo sublingual tablet
Drug
Lead sponsor
Melt Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
528 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
12
States / cities
Chico, California • Grand Junction, Colorado • Jacksonville, Florida + 9 more
Completed Not applicable Interventional Results available

Evaluating Two Multifocal Daily Disposable Contact Lenses

NCT05579886
Conditions
Presbyopia
Interventions
Control Lens, Test Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
42 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
5
States / cities
Ocoee, Florida • Pittsburg, Kansas • Vestal, New York + 2 more
Completed Not applicable Interventional Accepts healthy volunteers

Study of Soft Contact Lens Use With 7 Day Extended Wear

NCT00597467
Conditions
Ametropia
Interventions
VISA (comfilcon A) Silicone Hydrogel Soft contact lens, Acuvue 2 Soft Contact Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
23
States / cities
La Mesa, California • San Diego, California • Santa Monica, California + 17 more