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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Control lenses Clear all
Completed Not applicable Interventional Results available

Together Overcoming Diabetes

NCT04734015
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Together Overcoming Diabetes (TOD)
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
10 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Duluth, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 17, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

NCT06034327
View directory record Official record
Conditions
Myopia, Juvenile Myopia, Myopia Progression
Interventions
Single vision, impact-resistant spectacle lenses; Test Arm, Single vision, impact-resistant spectacle lenses; Control Arm
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 8 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
14
States / cities
Oakland, California • San Diego, California • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Dec 28, 2025 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Results available

Clinical Trial of a Hydrophilic EMV Toric Lens RAO210T in the Correction of Aphakia and Corneal Astigmatism

NCT05985304
View directory record Official record
Conditions
Cataract, Corneal Astigmatism
Interventions
RayOne EMV Toric IOL, RayOne Monofocal IOL, Cataract Surgery
Device · Procedure
Lead sponsor
Rayner Intraocular Lenses Limited
Industry
Eligibility
22 Years and older
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
9
States / cities
Fayetteville, Arkansas • Grand Junction, Colorado • Alexandria, Minnesota + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 17, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional

Direct vs Standard SLT for Glaucoma: A Noninferiority Trial

NCT07408154
View directory record Official record
Conditions
Open-angle Glaucoma (OAG), Ocular Hypertension (OHT)
Interventions
Direct Selective laser Trabeculoplasty
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional

Clinical Performance Evaluation of Two Daily Disposable Silicone Hydrogel Toric Contact Lenses

NCT04254003
View directory record Official record
Conditions
Refractive Errors
Interventions
DT1 Toric contact lenses, AO1DfA contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
2
States / cities
Maitland, Florida • Eden Prairie, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Connecting Contact Lenses and Digital Technology

NCT02921087
View directory record Official record
Conditions
Asthenopia, Contact Lenses, Ocular Accommodation, Convergence, Excess
Interventions
Test Daily Disposable Soft Contact Lenses, Control Daily Disposable Soft Contact Lenses
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years to 35 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of a Scleral Lens on the Anterior Chamber Depth and Minimum Rim Width

NCT03926975
View directory record Official record
Conditions
Ocular Hypertension
Interventions
Scleral Lens, No lens
Device · Other
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 60 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Self-Stigma Among Individuals with History of Childhood Maltreatment: a Cross-Cultural Lens

NCT06159075
View directory record Official record
Conditions
Stigma, Social, Child Abuse, Child Neglect, Help-Seeking Behavior
Interventions
Video
Behavioral
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years to 80 Years
Enrollment
964 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Sep 17, 2026, 11:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Multimodal Ocular Imaging in Neurodegeneration

NCT03699644
View directory record Official record
Conditions
Alzheimer Disease, Alzheimer Dementia, Frontotemporal Dementia
Interventions
Spectral-Domain Optical Coherence Tomography (SD-OCT), Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), Comprehensive Ophthalmic Examination, Fundus Photography
Device · Diagnostic Test
Lead sponsor
University of Michigan
Other
Eligibility
45 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 27, 2022 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Results available

Performance Evaluation of Different Daily Disposable Multifocal Contact Lenses

NCT05763628
View directory record Official record
Conditions
Presbyopia
Interventions
Control Lens (stenfilcon A), Test Lens (senofilcon A)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
42 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Vestal, New York • Athens, Ohio • Bellaire, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2024 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurolens Headache Study

NCT05070767
View directory record Official record
Conditions
Binocular Vision Disorder, Convergence Insufficiency, Headache, Computer Vision Syndrome
Interventions
Neurolens spectacle lens, Placebo spectacle lens
Device
Lead sponsor
Neurolens Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
10
States / cities
Phoenix, Arizona • Conyers, Georgia • Perry, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Sep 17, 2026, 11:08 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of The Comfort of Orthokeratology Lenses Fit Using A New Software

NCT05389072
View directory record Official record
Conditions
Myopia
Interventions
control contact lens
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
6 Years to 35 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
3
States / cities
San Diego, California • Glenview, Illinois • Bellaire, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2022 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Myopia Assessment of Two Manufacturing Processes

NCT04126057
View directory record Official record
Conditions
Juvenile Myopia
Interventions
SightGlass Vision DOT Spectacle Lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 14 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
5
States / cities
Longwood, Florida • Pittsburg, Kansas • Raytown, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2022 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Phase 3 Interventional

Evaluation of Efficacy and Safety of an Anti-Allergy Drug With a Contact Lens in the Treatment of Allergic Conjunctivitis

NCT00445874
View directory record Official record
Conditions
Allergic Conjunctivitis
Interventions
Ketotifen with a Contact Lens (no generic name)
Drug
Lead sponsor
Vistakon Pharmaceuticals
Industry
Eligibility
8 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
7
States / cities
Phoenix, Arizona • Irvine, California • North Andover, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2009 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional

A Comparison of Interventions to Teach Melanoma Patients Skin Self-examination

NCT01432860
View directory record Official record
Conditions
Melanoma
Interventions
In-person counseling, Workbook, Tablet Computer-Based Education
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 80 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 11, 2016 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy of KPI-121 in Subjects With Postsurgical Inflammation

NCT02163824
View directory record Official record
Conditions
Ocular Infections, Irritations and Inflammations
Interventions
KPI-121 0.25%, KPI-121 1.0%, Vehicle of KPI-121 0.25%, Vehicle of KPI-121 1.0%
Drug
Lead sponsor
Kala Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
23
States / cities
Artesia, California • Mission Hills, California • Rancho Cordova, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

NCT06749496
View directory record Official record
Conditions
Astigmatism
Interventions
Test Lens, Control Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
12
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Results available

A Clinical Study to Evaluate The Safety and Effectiveness of Performing 0.50 Diopter Astigmatism Correction on the Commercially Available RxSight Light Adjustable Lens (LAL)

NCT04005586
View directory record Official record
Conditions
Aphakia, Cataract
Interventions
Light Delivery Device (LDD)
Device
Lead sponsor
RxSight, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Brecksville, Ohio • Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Sep 17, 2026, 11:08 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Molding Process

NCT03605303
View directory record Official record
Conditions
Refractive Error Correction
Interventions
Test/Control, Control/Test
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Phase 3 Interventional Results available

A Randomized Study in Children Ages Birth Through Three Years Undergoing Unilateral Cataract Extraction With or Without Lens Replacement

NCT02132312
View directory record Official record
Conditions
Unilateral Cataract Extraction, Congenital Cataract
Interventions
OMS302, Phenylephrine HCl
Drug
Lead sponsor
Omeros Corporation
Industry
Eligibility
1 Day to 47 Months
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
11
States / cities
Los Angeles, California • Atlanta, Georgia • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2021 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Accommodative Responses of Soft Contact Lenses for Myopia Control

NCT03635528
View directory record Official record
Conditions
Visual Acuity
Interventions
Test Lens 1, Test Lens 2, Test Lens 3, Test Lens 4, Test Lens 5, Control Lens 1, Control Lens 2
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 25 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Sep 17, 2026, 11:08 PM EDT
Terminated Not applicable Interventional Results available

Clinical Investigation of the TECNIS® Next-Generation Intraocular Lens, Model DEN00V

NCT05574959
View directory record Official record
Conditions
Cataracts
Interventions
investigational IOL Model DEN00V, control IOL Model ZCB00/DCB00
Device
Lead sponsor
Johnson & Johnson Surgical Vision, Inc.
Industry
Eligibility
22 Years and older
Enrollment
243 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
10
States / cities
Bakersfield, California • Long Beach, California • Torrance, California + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Influence of Immersive Virtual Field Trips on Academic Vocabulary

NCT05242575
View directory record Official record
Conditions
Developmental Language Disorder, Language Disorders in Children
Interventions
The information provided in the iVFT and control book parallel one another.
Behavioral
Lead sponsor
Salus University
Other
Eligibility
6 Years to 8 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Sep 17, 2026, 11:08 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers

NCT00569777
View directory record Official record
Conditions
Allergic Conjunctivitis
Interventions
K-Lens (generic name not established) and Ketotifen, Placebo Lens
Device
Lead sponsor
Vistakon Pharmaceuticals
Industry
Eligibility
8 Years and older
Enrollment
310 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
3
States / cities
Gardena, California • North Andover, Massachusetts • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 5, 2015 · Synced Sep 17, 2026, 11:08 PM EDT