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ClinicalTrials.gov public records Last synced Nov 14, 2026, 10:33 PM EST

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Showing 25–48 of 117 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Creatine Supplementation Clear all

Conditions: Elevated S-adenosylhomocysteine
Interventions: Alpha-GPC, Creatine and Ashwagandha (Sensoril®), Placebo; Dietary Supplement · Other
Lead sponsor: Standard Process Inc.; Industry
Eligibility: 30 Years to 75 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: South Gate, California

Conditions: Cognitive Disorder, Metabolic Disease, Autism Spectrum Disorder
Interventions: Not listed
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 2 Years to 40 Years · Male only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Physical Fitness
Interventions: Creatine Monohydrate, Rice Flour; Dietary Supplement
Lead sponsor: David Grant U.S. Air Force Medical Center; Federal
Eligibility: 18 Years to 89 Years
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Fairfield, California

Conditions: Huntington Disease
Interventions: Creatine monohydrate, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 26 Years and older
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: Creatine Monohydrate; Drug
Lead sponsor: The Avicena Group; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 107 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 8
States / cities: San Francisco, California • Kansas City, Kansas • Albuquerque, New Mexico + 5 more

Conditions: Cognitive Function Assessment, Mental Fatigue
Interventions: Creatine Monohydrate, Maltodextrin Placebo; Dietary Supplement
Lead sponsor: University of Northern Iowa; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Cedar Falls, Iowa

Conditions: Gastrointestinal Cancer, Gastrointestinal Neoplasms, Colorectal Cancer, Colorectal Neoplasms, Colorectal Carcinoma, Gastric Cancer, Gastric Neoplasm, KRAS Mutation-Related Tumors, CRC, Colorectal Cancer Metastatic
Interventions: ompenaclid, FOLFIRI, Bevacizumab, FOLFOX regimen; Drug
Lead sponsor: Inspirna, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 89 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2025
U.S. locations: 17
States / cities: Prescott Valley, Arizona • Tucson, Arizona • Los Angeles, California + 14 more

Conditions: Creatine
Interventions: Creatine, Placebo; Dietary Supplement
Lead sponsor: University of Idaho; Other
Eligibility: 18 Years to 24 Years · Female only
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Moscow, Idaho

Conditions: Tourette Syndrome
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 14 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2015
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Nutritional Status
Interventions: Whey protein and creatine supplement, Whey protein only supplement, Placebo; Dietary Supplement
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 35 Years · Male only
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Progressive Supranuclear Palsy
Interventions: Pyruvate, creatine, niacinamide, Placebo; Dietary Supplement
Lead sponsor: University of Louisville; Other
Eligibility: Not listed
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2009
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Cardiac Function and Hemodynamics
Interventions: Creatine Monohydrate, Maltodextrin; Dietary Supplement
Lead sponsor: Radford University; Other
Eligibility: 55 Years to 80 Years · Male only
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Breast Cancer, Triple Negative Breast Cancer
Interventions: Carboplatin, Paclitaxel, Doxorubicin, Cyclophosphamide, Pegfilgrastim, Filgrastim; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 74 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 6
States / cities: Rockford, Illinois • Madison, Wisconsin • Milwaukee, Wisconsin + 2 more

Conditions: Muscle Injury
Interventions: Healthy Muscle Group, Stretch-Contract Pre-rehabilitation Group, Stretch-Contract Control Group, Muscle Atrophy; Procedure
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 40 Years
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Creatine Deficiency, X-linked
Interventions: Not listed
Lead sponsor: Ultragenyx Pharmaceutical Inc; Industry
Eligibility: 6 Months to 65 Years · Male only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 9
States / cities: La Jolla, California • Chicago, Illinois • Bethesda, Maryland + 6 more

Conditions: Venous Thromboembolism
Interventions: fondaparinux sodium, sequential compression devices; Drug · Device
Lead sponsor: Mary Knudson, M.D.; Other
Eligibility: 18 Years and older
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Amyotrophic Lateral Sclerosis
Interventions: Celecoxib, Creatine, Minocycline; Drug
Lead sponsor: Columbia University; Other
Eligibility: 21 Years to 85 Years
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 19
States / cities: Phoenix, Arizona • Los Angeles, California • Orange, California + 15 more

Conditions: Post-partum, Women
Interventions: Creatine Monohdyrate; Dietary Supplement
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Depression, Dual Diagnosis, Drug Addiction
Interventions: Creatine monohydrate; Drug
Lead sponsor: Perry Renshaw; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2023
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Angelman Syndrome, Nervous System Diseases
Interventions: Betaine, Creatine, Metafolin, Vitamin B12; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 1 Day to 5 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 4
States / cities: San Diego, California • Boston, Massachusetts • Greenwood, South Carolina + 1 more

Conditions: Huntington's Disease
Interventions: Creatine Monohydrate; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 26 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: Parkinson's Disease
Interventions: minocycline, creatine; Drug
Lead sponsor: University of Rochester; Other
Eligibility: 30 Years and older
Enrollment: 195 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Bipolar I Disorder, Psychosis, Schizoaffective Disorder
Interventions: Ketogenic diet, Dietary Guidelines for Americans; Other
Lead sponsor: Mclean Hospital; Other
Eligibility: 18 Years to 45 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Healthy
Interventions: Creatine, Maltodextrin; Dietary Supplement
Lead sponsor: Rocky Mountain University of Health Professions; Other
Eligibility: 19 Years to 30 Years
Enrollment: 47 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Provo, Utah

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Role of a Dietary Supplement in Lowering SAH in Healthy Adults With Elevated Plasma SAH and Normal Homocysteine Levels

Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency

Measuring Uniformed Servicemembers' Fitness Scores on Creatine Loading and Exercise

Creatine Safety and Tolerability in Premanifest HD: PRECREST

Study of Creatine Monohydrate in Patients With Amyotrophic Lateral Sclerosis

Effects of Short-Term Creatine Supplementation on Cognitive Function in Healthy Young Adults

A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer

Creatine Supplementation in Female Collegiate Dancers

Magnetic Resonance Spectroscopy to Evaluate Tourette s Syndrome

Effect of Using Whey Protein and Creatine Supplements on Muscular Strength in Weight-training Adult Males

A Pilot Clinical Trial of Pyruvate, Creatine, and Niacinamide in Progressive Supranuclear Palsy.

Cardiac and Vascular Responses to Creatine Supplementation in Elderly Men

Neoadjuvant Carbo/Paclitaxel Followed by Doxorubicin/Cyclophosphamide in Breast Cancer

Muscle Injury Prevention & Rehabilitation in Military Personnel

Observational Study of Males With Creatine Transporter Deficiency

The Use of Fondaparinux in Preventing Thromboembolism in High Risk Trauma Patients

Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis

Creatine for Recovery and Thinking in Mothers

A Randomized Double-Blind Controlled Trial of Creatine in Female Methamphetamine Users

Dietary Supplements for the Treatment of Angelman Syndrome

Premanifest Huntington's Disease: Creatine Safety & Tolerability Extension Study

National Institute of Neurological Disorders and Stroke (NINDS) Parkinson's Disease Neuroprotection Trial

Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder

Creatine Timing on Resistance Training Adaptations in College Athletes