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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:12 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 117 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Creatine Supplementation Clear all

Conditions: Muscular Dystrophy, Duchenne
Interventions: Creatine Monohydrate, Glutamine; Drug
Lead sponsor: Cooperative International Neuromuscular Research Group; Network
Eligibility: 5 Years to 9 Years · Male only
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2006
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Tyrosol, Creatine, Endurance Performance, Cognition
Interventions: Tyrosol, Creatine, Resistant Dextrin; Dietary Supplement
Lead sponsor: Applied Science & Performance Institute; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Major Depressive Disorder
Interventions: Low Dose 5-hydroxytryptophan, High Dose 5-hydroxytryptophan, Low Dose Creatine Monohydrate, High Dose Creatine Monohydrate, Placebo; Drug
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 65 Years
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Vaccine Adverse Reaction, Post Acute Covid-19 Vaccination Syndrome
Interventions: Combined metabolic modulator, Rice Protein Powder with Vitamin C; Combination Product · Dietary Supplement
Lead sponsor: Independent Medical Alliance; Other
Eligibility: 16 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Sarcopenia
Interventions: Resistance Training, Successful Aging; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 70 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Gainesville, Florida

Conditions: Physical Inactivity
Interventions: Creatine Monohydrate, Blood Flow Restriction, Exercise; Dietary Supplement · Device · Other
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years to 35 Years · Female only
Enrollment: 68 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Physical Performance, Exercise Performance, Endurance Exercise, Perceived Exertion, Mood, Energy
Interventions: proprietary pre-workout supplement, Control placebo; Dietary Supplement
Lead sponsor: Applied Science & Performance Institute; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Dietary Modification
Interventions: C4 Extreme, C4 Extreme (without Advantra Z, Placebo; Dietary Supplement
Lead sponsor: Texas A&M University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: College Station, Texas

Conditions: Acute Kidney Injury, Exertional Heat Illness
Interventions: Creatine Monohydrate, Maltodextrin (Placebo); Dietary Supplement
Lead sponsor: University of Northern Iowa; Other
Eligibility: 18 Years to 45 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Cedar Falls, Iowa

Conditions: Amyotrophic Lateral Sclerosis
Interventions: Creatine; Drug
Lead sponsor: National Center for Research Resources (NCRR); NIH
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Creatine Synthesis in Healthy Subjects
Interventions: Creatine and Amino Acid supplement; Dietary Supplement
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 20 Years to 35 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Huntington's Disease
Interventions: Creatine Monohydrate, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 553 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 38
States / cities: Birmingham, Alabama • Irvine, California • Sacramento, California + 35 more

Conditions: Peripheral Arterial Disease
Interventions: Creatine monohydrate, Cellulose; Drug · Dietary Supplement
Lead sponsor: Florida State University; Other
Eligibility: 40 Years to 95 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Endothelial Dysfunction, Oxidative Stress
Interventions: Creatine monohydrate, Placebo; Dietary Supplement
Lead sponsor: Florida State University; Other
Eligibility: 50 Years to 64 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Primary Lateral Sclerosis, Hereditary Spastic Paraplegia, Amyotrophic Lateral Sclerosis
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: Not listed
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2003
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Obesity, Women (Between 30 to 60 Years Old)
Interventions: Protein Rich Foods; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 30 Years to 60 Years · Female only
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Austin, Texas

Conditions: Huntington's Disease
Interventions: Creatine monohydrate; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 26 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: Cancer of Ovary, Cancer of the Ovary, Neoplasms, Ovarian, Ovarian Cancer, Ovary Cancer, Ovary Neoplasms
Interventions: Cisplatin + celecoxib + DC vaccine, Cisplatin + CKM + Celecoxib + DC Vaccine; Biological
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania

Conditions: Asperger's Disorder
Interventions: Risperidone, Magnetic Resonance Spectroscopy; Drug · Other
Lead sponsor: Augusta University; Other
Eligibility: 6 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2007
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Major Depressive Disorder
Interventions: Creatine Monohydrate; Drug
Lead sponsor: University of Utah; Other
Eligibility: 20 Years to 64 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Atrial Fibrillation
Interventions: Vitamin K antagonist, Apixaban; Drug
Lead sponsor: Atrial Fibrillation Network; Other
Eligibility: 18 Years and older
Enrollment: 676 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 5
States / cities: New York, New York • Philadelphia, Pennsylvania • Nashville, Tennessee + 2 more

Conditions: Exercise Performance Recovery
Interventions: Creatine Monohydrate, Carbohydrate, Creatine Monohydrate and Carbohydrate, placebo solution; Dietary Supplement
Lead sponsor: California Polytechnic State University-San Luis Obispo; Other
Eligibility: 18 Years to 40 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: San Luis Obispo, California

Conditions: Mature B-Cell Malignancies
Interventions: Sonrotoclax, Zanubrutinib, Obinutuzumab; Drug
Lead sponsor: BeOne Medicines; Industry
Eligibility: 18 Years and older
Enrollment: 437 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 13
States / cities: Los Angeles, California • Chicago, Illinois • Kansas City, Kansas + 9 more

Conditions: Lean Muscle Development, Muscular Endurance, Hormone-Related Wellness, Digestive Comfort, Dermatologic Health, Overall Wellness
Interventions: Shelf Builder Women's Creatine Powder; Dietary Supplement
Lead sponsor: Clean Nutraceuticals; Industry
Eligibility: 21 Years to 45 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Las Vegas, Nevada

Search by objective public record fields.

Creatine and Glutamine in Steroid-Naive Duchenne Muscular Dystrophy

The Effects of Tyrosol and Creatine on Endurance, Strength, and Fatigue Resistance in Healthy Adults

5-HTP and Creatine for Depression R33 Phase

Effect of Metabolic Modulation on a Post-acute COVID-19 Vaccination Syndrome (PACVS) Cohort

Time Course Adaptations Using Deuterated Creatine (D3Cr) Method

Blood Flow Restriction and Creatine Supplementation in Women

The Acute Effects of Liquid IV's Pre-Workout Supplement on Muscle Endurance & Strength, Energy, and Cognition

Assessment of a Pre-Workout Dietary Supplement

Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat

Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis [ALS]

Creatine Kinetics, Synthesis From Glycine and Response to Creatine and Amino Acid Supplement in Healthy Humans

Creatine Safety, Tolerability, & Efficacy in Huntington's Disease (CREST-E)

Creatine Use and Muscle Stretching in Peripheral Artery Disease

Creatine Monohydrate Supplementation and Vascular Endothelial Health

Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis

Increased Dietary Protein Intake During GLP-1 Medication Use (in Middle-aged Women With Overweight/Obesity)

Premanifest Huntington's Disease Extension Study II: Creatine Safety & Tolerability

Intensive Locoregional Chemoimmunotherapy for Recurrent Ovarian Cancer Plus Intranodal DC Vaccines

Janssen Asperger's MRS (Magnetic Resonance Spectroscopy Risperidone Study

Creatine for Treatment of Depression Associated With Type 2 Diabetes

Apixaban During Atrial Fibrillation Catheter Ablation: Comparison to Vitamin K Antagonist Therapy

Effects of Creatine and Carbohydrate Supplementation on Endurance Performance

Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell Malignancies

A Clinical Trial to Evaluate the Effects of a Powder Supplement in Supporting Lean Muscle Development, Hormone-Related Wellness, Digestive Comfort, Dermatologic Health, and Overall Wellness