- Conditions
- Glaucoma
- Interventions
- Restasis, Endura (artificial tears)
- Drug
- Lead sponsor
- Wills Eye
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 40
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Keratoconjunctivitis Sicca
- Interventions
- cyclosporine, vehicle of OTX-101
- Drug
- Lead sponsor
- Sun Pharmaceutical Industries Limited
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 745 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 3
- States / cities
- Rancho Cordova, California • Edgewood, Kentucky • New York, New York
- Conditions
- Dry Eye Syndromes
- Interventions
- CP-690,550, Cyclosporine, CP-690,550 Vehicle
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 327 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 27
- States / cities
- Chandler, Arizona • Peoria, Arizona • Phoenix, Arizona + 22 more
- Conditions
- Allergic Conjunctivitis
- Interventions
- CsA high dose, CsA low dose, PA, Placebo
- Drug
- Lead sponsor
- Fovea Pharmaceuticals SA
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 716 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 1
- States / cities
- Andover, Massachusetts
- Conditions
- Dry Eye
- Interventions
- Cyclosporine A 0.05%, Arificial Tear
- Drug
- Lead sponsor
- Massachusetts Eye and Ear Infirmary
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2010
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Dry Eye Syndromes
- Interventions
- cyclosporine 0.05% ophthalmic emulsion, carboxymethylcellulose-based lubricant eye drops
- Drug
- Lead sponsor
- Allergan
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014
- U.S. locations
- 1
- States / cities
- Andover, Massachusetts
- Conditions
- Allergic Conjunctivitis
- Interventions
- Prednisolone Acetate 0.12% (Pred Mild®), FOV1101-00, Prednisolone Acetate 1% (Pred Forte®), Placebo
- Drug
- Lead sponsor
- Fovea Pharmaceuticals SA
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 155 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009
- U.S. locations
- 1
- States / cities
- Andover, Massachusetts
- Conditions
- Dry Eye Syndromes
- Interventions
- Cyclosporine A, Placebo
- Drug
- Lead sponsor
- Novaliq GmbH
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 207 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 4
- States / cities
- Newport Beach, California • Lewiston, Maine • Andover, Massachusetts + 1 more
- Conditions
- Dry Eye Disease
- Interventions
- Vevye®, Xiidra®
- Drug
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 378 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 8
- States / cities
- Newport Beach, California • Louisville, Kentucky • Andover, Massachusetts + 5 more
- Conditions
- Keratoconjunctivitis Sicca
- Interventions
- Lotemax, Restasis, Soothe® Lubricant Eye Drops
- Drug
- Lead sponsor
- Bausch & Lomb Incorporated
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Irvine, California
- Conditions
- Dry Eye Disease (DED)
- Interventions
- CyclASol Ophthalmic Solution
- Drug
- Lead sponsor
- Novaliq GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 202 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 14
- States / cities
- Los Angeles, California • Newport Beach, California • Carmel, Indiana + 11 more
- Conditions
- Laser In Situ Keratomileusis
- Interventions
- Cyclosporine 0.010% eye drops, Cyclosporine 0.005% eye drops, Placebo (Vehicle for Cyclosporine)
- Drug
- Lead sponsor
- Allergan
- Industry
- Eligibility
- 21 Years to 50 Years
- Enrollment
- 621 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 1
- States / cities
- Overland Park, Kansas
- Conditions
- Dry Eye Syndromes
- Interventions
- Euphrasia-based homeopathic therapy, Cyclosporin solution
- Drug
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2010
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Dry Eye, Dry Eye Syndromes, Sjogren's Syndrome
- Interventions
- Cyclosporine 0.09% Ophthalmic Solution
- Drug
- Lead sponsor
- Center for Ophthalmic and Vision Research, LLC
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Manhattan, New York
- Conditions
- Fungal Keratitis, Corneal Ulcer
- Interventions
- Cyclosporine A, Placebo Comparator: Placebo
- Drug · Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Dry Eye Disease
- Interventions
- CyclASol topical ocular, eye drops, Vehicle topical ocular, eye drops
- Drug
- Lead sponsor
- Novaliq GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 834 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 27
- States / cities
- Phoenix, Arizona • Los Angeles, California • Newport Beach, California + 23 more
- Conditions
- Meibomian Gland Dysfunction (MGD)
- Interventions
- Vevye(Cyclosporine 0.1% Ophthalmic Solution)
- Drug
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Atopic Keratoconjunctivitis
- Interventions
- Cyclosporin 0.05% ophthalmic
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Keratoconjunctivitis Sicca, Sjogren's Syndrome
- Interventions
- Cyclosporin A
- Drug
- Lead sponsor
- National Eye Institute (NEI)
- NIH
- Eligibility
- Not listed
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1997 – 2000
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Dry Eye
- Interventions
- Cyclosporine ophthalmic solution 0.1%
- Other
- Lead sponsor
- Neuro-Ophthalmology of Texas
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Dry Eye
- Interventions
- Cyclosporin 0.05% emulsion, Endura, Refresh artificial tears
- Drug
- Lead sponsor
- Baylor College of Medicine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Dry Eye
- Interventions
- Voclosporin Ophthalmic Solution, Restasis®
- Drug
- Lead sponsor
- Aurinia Pharmaceuticals Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018
- U.S. locations
- 7
- States / cities
- Garden Grove, California • Mission Hills, California • Rancho Cordova, California + 4 more
- Conditions
- Dry Eye
- Interventions
- nanomicellular cyclosporine 0.09%, Lifitegrast
- Drug
- Lead sponsor
- Toyos Clinic
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Dry Eye Disease, Endothelial Cell
- Interventions
- Cyclosporine ophthalmic solution, 0.1%, Saline solution, 0.6%
- Drug
- Lead sponsor
- Novaliq GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 204 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 6
- States / cities
- Newport Beach, California • Torrance, California • Garner, North Carolina + 3 more