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ClinicalTrials.gov public records Last synced Oct 19, 2026, 3:14 PM EDT

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Showing 49–72 of 209 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Decompression Clear all
Not yet recruiting Not applicable Interventional

Short Interval Postoperative Stereotactic Body Radiation Therapy (SBRT) After Surgical Intervention for Spine Metastases

NCT07346170
View directory record Official record
Conditions
Spine Metastasis, Stereotactic Body Radiation Therapy (SBRT)
Interventions
Stereotactic Body Radiation Therapy (SBRT), Computed Tomography (CT) Simulation, Magnetic Resonance Imaging (MRI), Questionnaires
Radiation · Procedure · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 19, 2026, 3:14 PM EDT
Completed Not applicable Interventional Results available

Prospective, Multi-Center Evaluation of the Efficacy of Peripheral Trigger Decompression Surgery for Migraine Headaches

NCT02351544
View directory record Official record
Conditions
Migraine Headaches
Interventions
Botulinum Toxin Type A, Surgery, Daily headache diary, Migraine Disability Assessment Test (MIDAS), Migraine Work and Productivity Loss Questionnaire (MWPLQ), Migraine-Specific Quality of Life Questionnaire (MSQ)
Drug · Procedure · Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
6
States / cities
San Francisco, California • Olathe, Kansas • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Oct 19, 2026, 3:14 PM EDT
Completed Phase 4 Interventional Results available

Study of Epidural Steroid Injection (ESI) Versus Minimally Invasive Lumbar Decompression (Mild®) in Patients With Symptomatic Lumbar Central Canal Stenosis

NCT00995371
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
MILD® (Minimally Invasive Lumbar Decompression), Epidural Steroid Injection
Device · Drug
Lead sponsor
Coastal Orthopedics & Sports Medicine
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Nov 15, 2013 · Synced Oct 19, 2026, 3:14 PM EDT
Recruiting Phase 3 Interventional

Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression

NCT05058287
View directory record Official record
Conditions
Opioid Use, Lumbar Spinal Stenosis, Pain, Postoperative, Pain, Back
Interventions
Depo-Medrol 40Mg/Ml Suspension for Injection, Placebo
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 19, 2026, 3:14 PM EDT
Completed Phase 4 Interventional

Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis

NCT00000411
View directory record Official record
Conditions
Spinal Stenosis, Low Back Pain
Interventions
Decompressive laminectomy, Non-surgical treatments
Procedure · Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
289 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2015
U.S. locations
13
States / cities
Oakland, California • San Francisco, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Oct 19, 2026, 3:14 PM EDT
Completed Phase 4 Interventional Results available

(Botox) Mechanisms of Action in Altering the Molecular Environment in Which Pain Fibers Exist

NCT03381261
View directory record Official record
Conditions
Migraine
Interventions
Botulinum toxin type A
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Oct 19, 2026, 3:14 PM EDT
Active, not recruiting Not applicable Interventional

A 5-year Superion™ IDS Clinical Outcomes Post-Approval Evaluation (SCOPE)

NCT04192591
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Superion™ IDS device
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
45 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2041
U.S. locations
23
States / cities
Carlsbad, California • Larkspur, California • Rancho Mirage, California + 20 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 19, 2026, 3:14 PM EDT
Recruiting Early Phase 1 Interventional

Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant

NCT03964506
View directory record Official record
Conditions
Acute Myeloid Leukemia, Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, Atypical Chronic Myeloid Leukemia, Chronic Monocytic Leukemia, Myelofibrosis, Myelodysplastic/Myeloproliferative Neoplasm
Interventions
Hyperbaric oxygen
Drug
Lead sponsor
Omar Aljitawi
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 19, 2026, 3:14 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Age, Sex and Isometric Exercise on Ventricular-Vascular Interactions During Cardiac Unloading

NCT06939153
View directory record Official record
Conditions
Orthostatic Intolerance
Interventions
LBNP, LBNP + Isometric handgrip exercise
Other
Lead sponsor
Tracy Baynard
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 19, 2026, 3:14 PM EDT
Recruiting Phase 4 Interventional

Comparison of Outcomes of Management of Bowel Obstruction

NCT07084441
View directory record Official record
Conditions
Adhesive Small Bowel Obstruction
Interventions
Dexamethasone, Supportive Care
Drug · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
4
States / cities
New York, New York • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 19, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Partial Rotator Cuff Repair vs. Superior Capsular Reconstruction for Irreparable Rotator Cuff Tears

NCT04742452
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Superior Capusular Reconstruction, Partial Rotator Cuff Repair
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
3
States / cities
Chicago, Illinois • Cleveland, Ohio • Willoughby, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 19, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Driving After Cervical Spine Surgery

NCT02782923
View directory record Official record
Conditions
Cervical Disc Disease
Interventions
STISIM driving simulator
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2020 · Synced Oct 19, 2026, 3:14 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

NASA Exercise Prebreathe Study

NCT07702539
View directory record Official record
Conditions
Decompression Sickness
Interventions
Oxygen Prebreathe and Hypobaric Exposure
Procedure
Lead sponsor
Duke University
Other
Eligibility
30 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 19, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Measurement of Hemodynamic Responses to Lower Body Negative Pressure

NCT03582501
View directory record Official record
Conditions
Hypotension and Shock
Interventions
Lower body negative pressure
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 12, 2019 · Synced Oct 19, 2026, 3:14 PM EDT
Recruiting Not applicable Interventional

Spinal Decompression Plus Nerve Graft Implantation Following TSCI

NCT06243211
View directory record Official record
Conditions
Spinal Cord Injuries, Acute Traumatic Spinal Cord Injury
Interventions
DMED, ANGI
Procedure
Lead sponsor
Francis Farhadi
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 19, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Countermeasures for Visual Impairment in Astronauts

NCT05016414
View directory record Official record
Conditions
Space Flight Associated Neuro-ocular Syndrome
Interventions
Lower body negative pressure
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 8, 2021 · Synced Oct 19, 2026, 3:14 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

The Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral Head

NCT05706909
View directory record Official record
Conditions
Avascular Necrosis, Osteonecrosis
Interventions
Genex with ABMC
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 19, 2026, 3:14 PM EDT
Withdrawn Not applicable Interventional

Indirect vs. Direct Decompression for Treatment of Central Stenosis: RCT

NCT04708977
View directory record Official record
Conditions
Patients With Spinal Stenosis Indicated for LLIF
Interventions
One-level lateral lumbar interbody fusion with Indirect Decompression, One-level lateral lumbar interbody fusion with Direct Decompression
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Oct 19, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigating the Effects of Osteopathic Manipulative Treatment on Stress Management in Medical Students

NCT06125574
View directory record Official record
Conditions
Stress, Job, Student Burnout, Stress, Physiological, Stress, Psychological
Interventions
Osteopathic Manipulative Medicine
Other
Lead sponsor
The Touro College and University System
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 19, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating The Safety and Effectiveness of The NeoDisc™ Versus ACDF in Subjects With Single-Level Cervical Disc Disease

NCT00478088
View directory record Official record
Conditions
Cervical Disc Degenerative Disorder
Interventions
NeoDisc, Instrumented Anterior Cervical Discectomy and Fusion (ACDF)
Device
Lead sponsor
NuVasive
Industry
Eligibility
18 Years to 60 Years
Enrollment
488 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
22
States / cities
La Jolla, California • Marina del Rey, California • Santa Monica, California + 19 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 19, 2026, 3:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vertos Mild - Post Market Patient Outcomes

NCT01076244
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Minimally Invasive Lumbar Decompression
Procedure
Lead sponsor
The Center for Pain Relief, Inc.
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
2
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Apr 2, 2013 · Synced Oct 19, 2026, 3:14 PM EDT
Active, not recruiting Not applicable Interventional

SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion

NCT03570801
View directory record Official record
Conditions
Lumbar Spondylolisthesis, Grade 1 Spondylolisthesis, Lumbar Spinal Stenosis, Degenerative Spondylolisthesis
Interventions
Expert Panel Review
Other
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Enrollment
662 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
16
States / cities
Scottsdale, Arizona • San Francisco, California • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 19, 2026, 3:14 PM EDT
Not listed No phase listed Observational

Objective Measures of Nerve Integrity, Posture, Gait and Blood Flow, After Nerve Decompression

NCT01735903
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy
Interventions
Arm A - Non-Diabetic, Gait and Balance
Procedure
Lead sponsor
Foot Surgery Center of Northern Colorado
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2025
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 16, 2021 · Synced Oct 19, 2026, 3:14 PM EDT
Withdrawn Not applicable Interventional

Post-traumatic Occipital Neuralgia - Surgical Versus Medical Management

NCT03253523
View directory record Official record
Conditions
Post-Traumatic Neuralgia, Occipital Neuralgia
Interventions
Occipital neurolysis
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Oct 19, 2026, 3:14 PM EDT