Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 7:56 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 697–720 of 4,838 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional

OMT as an Adjunctive Treatment in MDD

NCT05065580
Conditions
Major Depressive Disorder
Interventions
Osteopathic Manipulative Treatment
Procedure
Lead sponsor
Corewell Health South
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Saint Joseph, Michigan
Conditions
Major Depressive Disorder, Depression
Interventions
Fluoxetine, Psychotherapy
Drug · Behavioral
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
12 Years to 17 Years
Enrollment
432 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2004
U.S. locations
12
States / cities
Chicago, Illinois • Baltimore, Maryland • Detroit, Michigan + 8 more
Conditions
HIV Infections, Fatigue
Interventions
Modafinil, Placebo
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
New York, New York
Completed Phase 4 Interventional Results available

Alternative Sedation During Bronchoscopy

NCT01158820
Conditions
Sedation
Interventions
Dexmedetomidine load, Ketamine load, Midazolam load, Fentanyl load, Dexmedetomidine maintenance, Ketamine maintenance, Midazolam demand, Fentanyl demand, Benadryl demand
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Major Depressive Disorder
Interventions
ANC-501
Drug
Lead sponsor
Ancora Bio, Inc. d/b/a EmbarkNeuro, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
8
States / cities
Orange, California • Largo, Florida • Lauderhill, Florida + 5 more
Conditions
Post Partum Depression
Interventions
Cognitive behavioral therapy (CBT) psychotherapy group/telehealth, Interpersonal therapy (IPT) psychotherapy group/telehealth
Behavioral
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Hackensack, New Jersey
Conditions
Depression, Anxiety
Interventions
Meru Health Program
Behavioral
Lead sponsor
Meru Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Completed No phase listed Observational

Long Term Follow Up KET-PD

NCT06164756
Conditions
Parkinson's Disease, Depression
Interventions
Cognitive Behavior Therapy (CBT), Treatment As Usual (TAU)
Other
Lead sponsor
Yale University
Other
Eligibility
40 Years to 80 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Multiple Sclerosis
Interventions
CRISP Program, Control Group
Behavioral · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
New York, New York
Conditions
Major Depressive Disorder, Bipolar Disorder, Healthy
Interventions
[18F]FPEB, [11C]APP311
Radiation
Lead sponsor
Yale University
Other
Eligibility
18 Years to 80 Years
Enrollment
79 participants
Timeline
2017 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Hydrate Heroes for Improving Brain Function & Mood

NCT07241260
Conditions
Hydration Status
Interventions
Hydrate Heroes (6 packets), Hydrate Heroes (3 packets)
Dietary Supplement
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Enrolling by invitation Not applicable Interventional

Activity and Recreation in Communities for Health

NCT06093282
Conditions
Depression
Interventions
ARCH, Traditional Health Outreach
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Impact of Giving a Massage

NCT01169480
Conditions
Mental State, Reported as Depression, Anxiety or Stress
Interventions
Give a massage
Behavioral
Lead sponsor
Parker Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Heart Failure, Congestive, Chronic Heart Failure, Depression
Interventions
Sertraline, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
45 Years and older
Enrollment
469 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Major Depressive Disorder
Interventions
AXS-05, Bupropion
Drug
Lead sponsor
Axsome Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
40
States / cities
Bellflower, California • Lafayette, California • Oceanside, California + 34 more
Conditions
Bipolar Disorder
Interventions
Seroquel®, quetiapine fumarate (atypical antipsychotic), lithium (mood stabilizer), divalproex (mood stabilizer)
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years and older
Enrollment
710 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
81
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Little Rock, Arkansas + 78 more
Conditions
Major Depressive Disorder (MDD), Treatment Resistant Depression, Major Depression
Interventions
MagVenture TMS Therapy System with Localite Navigation System and actiCHamp EEG
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
22 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Major Depression
Interventions
Family-based depression intervention, Usual care plus educational materials
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
50 Years and older · Male only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Stockton, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Parenting Skills Group for Mothers With Postpartum Depression

NCT05772897
Conditions
Postpartum Depression
Interventions
Circle of Security Parenting program
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2035
U.S. locations
1
States / cities
Denver, Colorado
Conditions
Bipolar Disorder
Interventions
levetiracetam
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Heart Defects, Congenital
Interventions
Not listed
Lead sponsor
Philip Moons
Other
Eligibility
18 Years and older
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
6
States / cities
Stanford, California • St Louis, Missouri • Omaha, Nebraska + 3 more
Conditions
Major Depressive Disorder
Interventions
Aripiprazole
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Parkinson's Disease
Interventions
Medtronic Activa PC+S System with Chronic Neural Recording, Effort-Reward Decision-Making Task, Prefrontal Cortex Stimulation, Tablet-Based Mood Tracking (Immediate Mood Scaler)
Device · Behavioral · Other
Lead sponsor
Simon J. Little, MBBS, PhD
Other
Eligibility
30 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
San Francisco, California
Conditions
Premenstrual Syndrome, Depression
Interventions
Drospirenone and ethinyl estradiol, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts