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ClinicalTrials.gov public records Last synced Oct 28, 2026, 1:37 AM EDT

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Showing 721–744 of 4,363 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Depression Scale Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of a Web-based Nursing Intervention in the Reduction of Postpartum Depression and Parenting Stress.

NCT02843022
View directory record Official record
Conditions
Depression, Postpartum
Interventions
standardized electronic messages, nurse phone call if requested, Staff nurse phone follow-up
Behavioral
Lead sponsor
Saint Anselm College
Other
Eligibility
18 Years and older · Female only
Enrollment
683 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Manchester, New Hampshire
Source: ClinicalTrials.gov public record
Updated Apr 23, 2018 · Synced Oct 28, 2026, 1:37 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Establishing Moderators and Biosignatures of Antidepressant Response for Clinical Care for Depression

NCT01407094
View directory record Official record
Conditions
Depression
Interventions
Sertraline, Placebo, BupropionXL
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
296 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
4
States / cities
Boston, Massachusetts • Ann Arbor, Michigan • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 26, 2018 · Synced Oct 28, 2026, 1:37 AM EDT
Completed Not applicable Interventional

Acupuncture for Symptoms of Nerve Damage

NCT03183037
View directory record Official record
Conditions
Peripheral Neuropathy, Chemotherapy-induced Peripheral Neuropathy
Interventions
Acupuncture, Sham Acupuncture, Usual Care Group, questionnaires
Procedure · Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
2
States / cities
Commack, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Oct 28, 2026, 1:37 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

A Cognitive Risk Calculator and Screening Tool for Primary Care Settings

NCT06506877
View directory record Official record
Conditions
Cognitive Risk Assessment
Interventions
Implementation of Cognitive Risk Calculator (RC) and Brief Assessment of Cognitive Health (BACH)
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 28, 2026, 1:37 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Comparison of Vocal Biomarkers for Depression and Anxiety to Formal Clinical Assessments

NCT06464575
View directory record Official record
Conditions
Depression/Anxiety
Interventions
Not listed
Lead sponsor
Ellipsis Health
Industry
Eligibility
18 Years and older
Enrollment
540 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 18, 2024 · Synced Oct 28, 2026, 1:37 AM EDT
Completed No phase listed Observational

Pediatric Bipolar Registry

NCT02360267
View directory record Official record
Conditions
Bipolar Disorder, Depression, Mania, Psychosis
Interventions
Not listed
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
6 Years to 17 Years
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 22, 2025 · Synced Oct 28, 2026, 1:37 AM EDT
Completed No phase listed Observational

The Association Between Gut Microbiota Diversity and Postpartum Depression

NCT07227753
View directory record Official record
Conditions
Depression During Pregnancy
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 28, 2026, 1:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessing Anterior Cingulate Brain Activity in People With Late-Life Depression

NCT00926653
View directory record Official record
Conditions
Depression
Interventions
Escitalopram
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years to 85 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2015 · Synced Oct 28, 2026, 1:37 AM EDT
Terminated No phase listed Observational

Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome

NCT01144741
View directory record Official record
Conditions
Freeman-Sheldon Syndrome, Arthrogryposis Distal Type 2A, Whistling Face Syndrome, Craniocarpotarsal Dysplasia, Craniocarpotarsal Dystrophy, Freeman-Sheldon Syndrome Variant, Sheldon-Hall Syndrome, Arthrogryposis Distal Type 2B, Gordon Syndrome, Arthrogryposis Distal Type 3, Arthrogryposis Distal Type 1, Arthrogryposis, Distal, Type 1A, Arthrogryposis Distal Type 1B, Arthrogryposis, Distal, Craniofacial Abnormalities, Arthrogryposis
Interventions
PTSD Checklist-Civilian (PCL-C), Modified Flanagan Quality of Life Scale, Center for Epidemiologic Studies Depression Scale (CES-D), Functional Enquiry (or Review of Systems) Form, Study of Therapeutic Outcomes and Practices in Freeman-Sheldon Syndrome (STOP-FSS) Questionnaire, FSRG Semi-Structured Quality of Life Interview (FSRG SSQLI), Medical Records Review
Other
Lead sponsor
Freeman-Sheldon Research Group, Inc.
Other
Eligibility
Not listed
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2022
U.S. locations
1
States / cities
Buckhannon, West Virginia
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Oct 28, 2026, 1:37 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

New Mothers Alpha-Stim

NCT04770181
View directory record Official record
Conditions
Anxiety, Depression, Insomnia, Sleep Quality
Interventions
Alpha-Stim AID CES (Active Comparator), Alpha-Stim AID CES (Sham Comparator)
Device
Lead sponsor
Christina Murphey, RN, PhD
Individual
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Austin, Texas • Corpus Christi, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 28, 2026, 1:37 AM EDT
Completed No phase listed Observational

Detection of Postoperative Respiratory Depression in High Risk Patients Utilizing Minute Ventilation Monitoring

NCT04017702
View directory record Official record
Conditions
Respiratory Depression
Interventions
Expiron respirator
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 80 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 1, 2022 · Synced Oct 28, 2026, 1:37 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

miRNAs, Suicide, and Ketamine - Plasma Exosomal microRNAs as Novel Biomarkers for Suicidality and Treatment Outcome

NCT02418195
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
ketamine
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
247 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 30, 2022 · Synced Oct 28, 2026, 1:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Investigating How Incentives Impact Engagement With an Online Mental Health Application (Neuroflow)

NCT05121675
View directory record Official record
Conditions
Behavioral Economics, Gifts, Financial, Point
Interventions
Neuroflow app: Mental health and wellbeing resources for adults
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 12, 2024 · Synced Oct 28, 2026, 1:37 AM EDT
Completed Not applicable Interventional Results available

Text 2 Connect- Texting Intervention for Mental Health Treatment Utilization

NCT04560075
View directory record Official record
Conditions
Depression, Suicidal Ideation
Interventions
Text2Connect, Psychoeducational Videos (PE) Only
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
3
States / cities
McMurray, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Oct 28, 2026, 1:37 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Treatment of Intrapartum Depression Using Non-invasive Photobiomodulation

NCT04404231
View directory record Official record
Conditions
Depression, Pregnancy Related, Intrapartum Depression
Interventions
Delivery of infrared light to the head, No Infrared treatment
Radiation · Other
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Oct 28, 2026, 1:37 AM EDT
Withdrawn Not applicable Interventional

Evaluating the Feasibility of Disseminating a Novel Mobile Platform to Treat Depression

NCT02817672
View directory record Official record
Conditions
Depression
Interventions
PRIME 1.0, PRIME 2.0
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Oct 28, 2026, 1:37 AM EDT
Completed Not applicable Interventional

Cognitive Behavioral Therapy for Depression Relapse Prevention in Children and Adolescents

NCT00158301
View directory record Official record
Conditions
Depression
Interventions
Cognitive behavioral therapy (CBT), Drug therapy
Behavioral · Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
11 Years to 18 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 8, 2013 · Synced Oct 28, 2026, 1:37 AM EDT
Completed Phase 2Phase 3 Interventional

Treatment of SSRI-Resistant Depression In Adolescents (TORDIA)

NCT00018902
View directory record Official record
Conditions
Depression
Interventions
Fluoxetine, Venlafaxine, Cognitive Behavioral Therapy (CBT), Citalopram
Drug · Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 18 Years
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
6
States / cities
Los Angeles, California • Portland, Oregon • Pittsburgh, Pennsylvania + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2014 · Synced Oct 28, 2026, 1:37 AM EDT
Completed Not applicable Interventional

Perinatal Depression Treatment in a Pediatric Setting- Pilot Phase

NCT00804739
View directory record Official record
Conditions
Postpartum Depression
Interventions
Mother-Infant Treatment Team
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 27, 2012 · Synced Oct 28, 2026, 1:37 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Rapid Diagnosis of MCI and Depression in Patients Ages 60 and Over

NCT06011681
View directory record Official record
Conditions
Depression, Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
Miro Health
Other
Eligibility
60 Years and older
Enrollment
960 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Sacramento, California • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 22, 2024 · Synced Oct 28, 2026, 1:37 AM EDT
Completed Not applicable Interventional Results available

Testing Scalable, Single-Session Interventions for Adolescent Depression in the Context of COVID-19

NCT04634903
View directory record Official record
Conditions
Depression
Interventions
Supportive Therapy SSI, Behavioral Activation SSI, Growth Mindset SSI
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
13 Years to 16 Years
Enrollment
2,452 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated May 25, 2021 · Synced Oct 28, 2026, 1:37 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Kappa Opioid Receptor Imaging in Depression (KOR Depression)

NCT02236702
View directory record Official record
Conditions
Major Depressive Disorder, Anhedonia
Interventions
Positron Emission Tomography (PET) imaging
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 55 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2016 · Synced Oct 28, 2026, 1:37 AM EDT
Completed Not applicable Interventional Results available

Depression and ART Adherence in HIV+ Latinos

NCT01411839
View directory record Official record
Conditions
Depressive Symptoms, HIV Infections
Interventions
Cognitive-Behavioral Therapy (CBT-AD)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Mar 19, 2018 · Synced Oct 28, 2026, 1:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Screening Study To Assess The Cognition Status in Healthy Volunteers

NCT01926873
View directory record Official record
Conditions
Healthy Volunteer
Interventions
Not listed
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years to 65 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
5
States / cities
San Diego, California • Atlanta, Georgia • Oak Brook, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2016 · Synced Oct 28, 2026, 1:37 AM EDT