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ClinicalTrials.gov public records Last synced Oct 23, 2026, 6:22 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 433–456 of 3,415 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: DiRECT Clear all
Active, not recruiting Not applicable Interventional

Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care

NCT04601064
View directory record Official record
Conditions
HIV Infections, Substance Use Disorders, Mental Health Disorder, Addiction, Opioid Use, Drug Use
Interventions
Collaborative Care Model
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
405 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 23, 2026, 6:22 PM EDT
Not listed Not applicable Interventional

Intestinal Inflammation and Carbohydrate Digestion in Autistic Children

NCT00227487
View directory record Official record
Conditions
Autism, Inflammation
Interventions
Stool collection, Administration of carbohydrate solution during clinically indicated endoscopy, Questionnaires
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Months to 17 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2017
U.S. locations
2
States / cities
Boston, Massachusetts • Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Oct 23, 2026, 6:22 PM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Electrical Inhibition (EI): A Preliminary Study To Inhibit Preterm Labor And Preterm Birth

NCT02569216
View directory record Official record
Conditions
Premature Birth, Premature Labor
Interventions
Electrical Inhibition (EI)
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 55 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Manhattan, New York
Source: ClinicalTrials.gov public record
Updated Nov 9, 2017 · Synced Oct 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Transcranial Direct Current Stimulation Intensity on Leg Muscle Fatigability in Healthy Adults

NCT04321304
View directory record Official record
Conditions
Healthy
Interventions
Sham transcranial direct current stimulation, Transcranial direct current stimulation at 2 mA, Transcranial direct current stimulation at 4 mA
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 30 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Oct 23, 2026, 6:22 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Osmotic Fragility in Red Blood Cells of Pediatric Patients With Cholestatic Liver Disease

NCT05582447
View directory record Official record
Conditions
Cholestasis, Red Cell Membrane and Enzyme Abnormalities
Interventions
ektacytometry of red blood cells
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Year and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 23, 2026, 6:22 PM EDT
Not listed No phase listed Observational

OPS™ With Direct Anterior Approach (DAA)

NCT04319952
View directory record Official record
Conditions
Primary Total Hip Arthroplasty
Interventions
Primary Total Hip Replacement with Metafix™ femoral stem and Trinity™ acetabular cup or TriFit-CF™/TriFit-TS™ femoral stem and Trinity™ acetabular cup implanted by a single surgeon.
Device
Lead sponsor
Corin
Industry
Eligibility
21 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Dallas, Texas • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Aug 24, 2021 · Synced Oct 23, 2026, 6:22 PM EDT
Not listed Not applicable Interventional

Safety and Efficacy Study of Deep Transcranial Magnetic Stimulation in Bipolar Depression

NCT01566591
View directory record Official record
Conditions
Bipolar Depression
Interventions
Deep TMS Treatment, Sham Treatment
Device
Lead sponsor
Brainsway
Industry
Eligibility
22 Years to 68 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
9
States / cities
Juno Beach, Florida • Palm Beach, Florida • Royal Palm Beach, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2021 · Synced Oct 23, 2026, 6:22 PM EDT
Not listed Not applicable Interventional

Fascial Scar Mobilization Techniques in Treating Chronic Caesarian Section Scar Pain

NCT02836626
View directory record Official record
Conditions
Cesarean Section, Cicatrix, Tissue Adhesions
Interventions
deep fascial mobilization, superficial fascial mobilization
Procedure
Lead sponsor
Rocky Mountain University of Health Professions
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Manchester, New Hampshire • McLean, Virginia • Lynnwood, Washington
Source: ClinicalTrials.gov public record
Updated Apr 11, 2017 · Synced Oct 23, 2026, 6:22 PM EDT
Active, not recruiting Not applicable Interventional

The Synergy Disc for the Treatment of 2 Level Cervical Degenerative Disc Disease Compared With Cervical Fusion Surgery

NCT05740176
View directory record Official record
Conditions
Cervical Degenerative Disc Disease
Interventions
Anterior Cervical Discectomy and Fusion
Device
Lead sponsor
Synergy Spine Solutions
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
23
States / cities
Scottsdale, Arizona • Beverly Hills, California • Los Angeles, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 23, 2026, 6:22 PM EDT
Terminated Phase 1 Interventional

Adaptive tDCS for Treatment-Resistant MDD

NCT02942368
View directory record Official record
Conditions
Depressive Disorder, Treatment-Resistant
Interventions
tDCS
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

Smartphone Based aDOT Treatment With Fixed-Dose Elbasvir and Grazoprevir in PWIDs

NCT03127358
View directory record Official record
Conditions
Hepatitis C, Medication Adherence
Interventions
AiCure, AiCure with gamification
Device
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 14, 2021 · Synced Oct 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Respiratory Disease Management

NCT01543217
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
RT management, Ususal care
Other
Lead sponsor
Barnes-Jewish Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
428 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 23, 2021 · Synced Oct 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Bicycling Intervention on Cognitive Skills and Cardiovascular Health

NCT02453178
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Cycling
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
60 Years to 80 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Oct 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility Study: Heavy Water Tissue Labeling Protocol

NCT01708525
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera® System Treatment, Heavy Water
Device · Other
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Dec 11, 2017 · Synced Oct 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

His Bundle Pacing Versus Coronary Sinus Pacing for Cardiac Resynchronization Therapy

NCT02700425
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
CRT Pacemaker
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
8
States / cities
Los Angeles, California • Chicago, Illinois • Naperville, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 23, 2026, 6:22 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Real-time Tumor Localization and Guidance for Radiotherapy Using Ultrasound (US) and Magnetic Resonance (MR)

NCT04095091
View directory record Official record
Conditions
Tumor, Solid
Interventions
4D Planar US Transducer
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Oct 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transdiagnostic Sleep and Anxiety Treatment

NCT03664310
View directory record Official record
Conditions
Anxiety Disorders
Interventions
FSET Anxiety and Sleep Treatment, Control
Other
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Oct 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Clinical Trial to Evaluate the Endoscopic Ultrasound Guided Celiac Plexus Block for Treatment of Pain in Chronic Pancreatitis

NCT03070210
View directory record Official record
Conditions
Pancreatitis, Chronic, Abdominal Pain
Interventions
EUS-celiac ganglia block (EUS-CGB), EUS-celiac plexus block (EUS-CPB)
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 17, 2020 · Synced Oct 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Medacta GMK Sphere® Multicenter Post-Market Outcomes Study

NCT02501733
View directory record Official record
Conditions
Osteoarthritis
Interventions
Medacta GMK Sphere® Medial Knee Prosthesis
Device
Lead sponsor
Medacta USA
Industry
Eligibility
21 Years to 80 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2024
U.S. locations
5
States / cities
Chicago, Illinois • New Orleans, Louisiana • Oklahoma City, Oklahoma + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Oct 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Modulation of Spontaneous Cortical Activity by tDCS: BRAIN Initiative I

NCT03672747
View directory record Official record
Conditions
Brain Function
Interventions
transcranial direct-current stimulation (tDCS)
Device
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 72 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 31, 2024 · Synced Oct 23, 2026, 6:22 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Foley With Oxytocin Versus Foley no Oxytocin for Induction of Labor

NCT02273115
View directory record Official record
Conditions
Labor; Forced or Induced, Affecting Fetus or Newborn
Interventions
Oxytocin, Transcervical Foley catheter
Drug · Device
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older · Female only
Enrollment
323 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Newark, Delaware • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Telehealth & HPV Self-Collection

NCT05089825
View directory record Official record
Conditions
Gynecologic Cancer
Interventions
Receive routine instructions, Telehealth-based instructional visit and receive routine instructions
Other
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
25 Years to 85 Years · Female only
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 16, 2023 · Synced Oct 23, 2026, 6:22 PM EDT
Completed No phase listed Observational

Comparison of ICG Microangiography and Conventional Angiography in Severe Frostbite

NCT05777590
View directory record Official record
Conditions
Frostbite
Interventions
Indocyanine Green Angiogram
Drug
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 23, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Estimating Energy Expenditure in Active Video Gaming Compared to Unstructured, Outdoor Play in Children

NCT01430715
View directory record Official record
Conditions
Motor Activity
Interventions
Active vido games and outdoor play
Other
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
5 Years to 8 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 23, 2026, 6:22 PM EDT