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Showing 1081–1104 of 3,417 matching trials from the live ClinicalTrials.gov search.
Completed Phase 1 Interventional Results available

Dose Dependent Effects of tDCS on Post-Operative Pain

NCT02241967
Conditions
Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty(Postoperative Pain)
Interventions
4 Real sessions of Transcranial Direct Current Stimulation, 2 Real Sessions of Transcranial Direct Current Stimulation, 1 Real Session of Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
19 Years to 90 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Major Depressive Disorder
Interventions
Transcranial direct current stimulation (t-DCS), Sham Controlled Arm
Device · Other
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Factors Affecting Sensory and Motor Learning

NCT05374460
Conditions
Basic Science
Interventions
Explanatory diagram, Direct vision, Movement feedback, target hand, Movement feedback, pointing hand, No movement feedback, Attend to the targets
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 45 Years
Enrollment
389 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Phase 4 Interventional Results available

deLIVER: Direct Acting Antiviral Effects on the Liver

NCT02938013
Conditions
HCV Coinfection, Liver Disease, HIV
Interventions
Sofosbuvir/Velpatasvir/Voxilaprevir [SOF/VEL/VOX], Sofosbuvir/Velpatasvir (SOF/VEL)
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Traumatic Brain Injury
Interventions
Anodal Transcranial Direct Current Stimulation, Sham stimulation
Device
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Facial Pain
Interventions
tDCS
Device
Lead sponsor
Beth Israel Medical Center
Other
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
New York, New York
Conditions
Osteoarthritis, Avascular Necrosis
Interventions
Total hip replacement components
Device
Lead sponsor
New Lexington Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Completed Not applicable Interventional

Planned Semi-Elective Lung Tx Study

NCT04601818
Conditions
To Compare Lung Transplant Outcomes Between Study Patients and Standard Patients Who Have Already Undergone Lung Transplantation by Conventional Procedures, Lung Transplant
Interventions
Experimental: Preserving of Donor Lungs
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Traumatic Brain Injury, Traumatic Brain Injury (TBI) Patients, Traumatic Brain Injury (TBI); Concussion, Initial Encounter, Traumatic Brain Injury (TBI); Concussion, Subsequent Encounter, Traumatic Brain Injury With Brief Loss of Consciousness, Traumatic Brain Injury With Persistent Cognitive Deficits
Interventions
MUSE Stem Cell Therapy
Biological
Lead sponsor
Healing Hope International
Other
Eligibility
6 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2028 – 2036
U.S. locations
1
States / cities
Houston, Texas
Conditions
Low Back Pain
Interventions
Flexion-Distraction (non-thrust) spinal manipulation
Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Davenport, Iowa
Conditions
Laparoscopic Myomectomy
Interventions
Sepraspray
Device
Lead sponsor
Genzyme, a Sanofi Company
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
3
States / cities
Naperville, Illinois • Philadelphia, Pennsylvania • Austin, Texas
Conditions
Self-Injurious Behavior, Self Harm, Self-injury, Self-inflicted Injury, Self Injurious Behavior Without Suicidal Intent, Non-Suicidal Self Injury, Non Suicidal Self Inflicted Injury, Cutting, Depression, Bipolar Disorder, Borderline Personality Disorder
Interventions
Transcranial direct current stimulation, No intervention
Device · Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
New York, New York
Conditions
ADHD, Depression Disorders, Mood Disorders, Anxiety Disorder Generalized, Bipolar Disorder (BPD)
Interventions
Prescription Psychotropic Medications
Drug
Lead sponsor
Gaize
Industry
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Terminated No phase listed Observational

Prospective Tumor Response Evaluation

NCT02787954
Conditions
Hepatocellular Cancer, Metastatic Liver Cancer
Interventions
TACE, Y-90, MWA, IRE
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Houston, Texas
Conditions
Health Records, Personal
Interventions
Personal Health Management System
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
7,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
3
States / cities
Brooklyn, New York • New York, New York • Rockville Centre, New York
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Antidepressant Therapy for Improved Blood Vessel Health After Preeclampsia

NCT07715669
Conditions
Preeclampsia, Endothelial Function
Interventions
Paroxetine Hydrochloride, Ascorbic acid (Vitamin C)
Drug
Lead sponsor
Anna Stanhewicz, PhD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smoking Cessation Self-Help for Dual Users of Tobacco Cigarettes and E-Cigarettes

NCT02416011
Conditions
Smoking Cessation
Interventions
GENERIC, eTARGET
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
2,896 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Anorexia Nervosa
Interventions
Interoceptive Exposure Treatment (IE), Family-Based Treatment (FBT)
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
12 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Lymphoma
Interventions
filgrastim, gemcitabine hydrochloride, vinorelbine tartrate
Biological · Drug
Lead sponsor
Children's Oncology Group
Network
Eligibility
Up to 30 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
108
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Downey, California + 93 more
Enrolling by invitation Not applicable Interventional

Individual Placement and Support Mexico

NCT06019247
Conditions
Severe Mental Disorder
Interventions
Individual placement support (IPS)
Other
Lead sponsor
Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente
Other
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
New York, New York
Conditions
Atrial Fibrillation
Interventions
Rivaroxaban (Xarelto, BAY59-7939), Vitamin K antagonist (VKA)
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
1,504 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
66
States / cities
Mobile, Alabama • Scottsdale, Arizona • East Palo Alto, California + 58 more
Conditions
Multiple Sclerosis
Interventions
eSupport Health Weekly Group Sessions for PwMS
Behavioral
Lead sponsor
eSupport Health
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Natural History Study of Early Life Exposures in Agriculture (ELEA)

NCT07328516
Conditions
Prostate Cancer, Leukemia, Breast Cancer, Melanoma, Colorectal Cancer
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 99 Years
Enrollment
64,277 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Active, not recruiting Not applicable Interventional

Mind Your Heart-II

NCT05431192
Conditions
Heart Failure, Cognitive Impairment
Interventions
Mindfulness Training + Enhanced Usual Care, Enhanced Usual Care
Behavioral · Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island