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Showing 1–24 of 91 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Dilator Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Radiofrequency and Hybrid Fractional Laser for Vaginal Rejuvenation

NCT03316950
View directory record Official record
Conditions
Vaginal Atrophy
Interventions
IntraGen RF, DiVA, Placebo (DIVA/IntraGen combined)
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
40 Years to 65 Years · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 3, 2023 · Synced Sep 6, 2026, 10:00 AM EDT
Completed Not applicable Interventional Results available

Cook Balloon vs Dilapan-S for Outpatient Cervical Ripening

NCT05062343
View directory record Official record
Conditions
Induced; Birth
Interventions
Dilapan-S, Cook Cervical Ripening Balloon
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Sep 6, 2026, 10:00 AM EDT
Completed Not applicable Interventional Results available

Pelvic Floor Physical Therapy vs Standard Care in Transgender Women Undergoing Vaginoplasty for Gender Affirmation

NCT05690555
View directory record Official record
Conditions
Pelvic Floor Disorders
Interventions
Preoperative and Postoperative Pelvic Floor Physical Therapy (PFPT), No Pelvic Floor Physical Therapy (PFPT), Postoperative PFPT
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Male only
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Sep 6, 2026, 10:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

OPIOID Study - Pain With Osmotic Dilators

NCT03710239
View directory record Official record
Conditions
Abortion in Second Trimester
Interventions
Dilapan-S, Laminaria
Device
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Mar 15, 2020 · Synced Sep 6, 2026, 10:00 AM EDT
Recruiting Not applicable Interventional

Vaginal Dilator Therapy After Pelvic Radiation

NCT07216456
View directory record Official record
Conditions
Pelvic Radiotherapy, Vaginal Stenosis, Pelvic Cancer, Gynecologic Cancers, Anorectal Cancer, Urologic Cancer
Interventions
Improving Engagement with Vaginal Dilator Therapy after Pelvic Radiation
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 6, 2026, 10:00 AM EDT
Recruiting Not applicable Interventional

Nasal Dilator Therapy for Patulous Eustachian Tube Dysfunction

NCT07796139
View directory record Official record
Conditions
Patulous Eustachian Tube Dysfunction, Eustachian Tube Dysfunction
Interventions
Internal nasal dilator
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 6, 2026, 10:00 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Benefits of the Use of Botox in the Treatment of Empty Nose Syndrome Syndrome

NCT00732680
View directory record Official record
Conditions
Empty Nose Syndrome, Atrophic Rhinitis
Interventions
Botulinum Toxin Type A
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 17, 2016 · Synced Sep 6, 2026, 10:00 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Dilapan-S® for Induction of Labor The Feasibility Study

NCT04521062
View directory record Official record
Conditions
Induction of Labor Affected Fetus / Newborn
Interventions
Dilapan S
Device
Lead sponsor
Albany Medical College
Other
Eligibility
Not listed
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Sep 6, 2026, 10:00 AM EDT
Completed No phase listed Observational

Dilapan-S/Dilasoft E-Registry in Induction of Labor

NCT02318173
View directory record Official record
Conditions
Labour Onset and Length Abnormalities, Labor; Forced or Induced, Affecting Fetus or Newborn
Interventions
Dilapan-S
Device
Lead sponsor
Medicem International CR s.r.o.
Industry
Eligibility
Female only
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
New York, New York • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated May 18, 2017 · Synced Sep 6, 2026, 10:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During Cervical Dilator Placement Prior to Dilation and Evacuation

NCT03868787
View directory record Official record
Conditions
Pain Management
Interventions
TENS, Sham TENS
Device
Lead sponsor
Ashley Turner, MD
Other
Eligibility
18 Years and older · Female only
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Sep 6, 2026, 10:00 AM EDT
Terminated Not applicable Interventional

An Evaluation of the Medtronic Gatekeeper System in the Treatment of SUBJECTS With Gastroesophageal Reflux Disease (GERD)

NCT00200044
View directory record Official record
Conditions
Gastroesophageal Reflux Disease
Interventions
Gatekeeper Reflux Repair System
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
10
States / cities
San Francisco, California • Atlanta, Georgia • Chicago, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2009 · Synced Sep 6, 2026, 10:00 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Cervical Preparation With Mifepristone Prior to Osmotic Dilators

NCT03714880
View directory record Official record
Conditions
Second Trimester Abortion
Interventions
Mifepristone 200 MG, Placebo Oral Tablet
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 7, 2022 · Synced Sep 6, 2026, 10:00 AM EDT
Completed Phase 3 Interventional Results available

Reducing Diagnostic Error to Improve Patient Safety in COPD and Asthma (REDEFINE Study)

NCT03137303
View directory record Official record
Conditions
COPD Asthma
Interventions
Spirometry at initial visit, Albuterol, Spirometry at 12-month follow-up
Device · Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
40 Years and older
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 25, 2024 · Synced Sep 6, 2026, 10:00 AM EDT
Completed Not applicable Interventional Results available

Induction of Labor in Women With Unfavorable Cervix: Dilapan Versus Foley Bulb

NCT02899689
View directory record Official record
Conditions
Pre-induction Dilation of Cervix
Interventions
Dilapan, Foley Catheter
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
419 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Sep 6, 2026, 10:00 AM EDT
Completed Not applicable Interventional Results available

Outcomes of Esophageal Self Dilation for Benign Refractory Esophageal Stricture Management

NCT03738566
View directory record Official record
Conditions
Esophageal Dilation, Refractory Benign Esophageal Stricture
Interventions
Esophageal self-dilation therapy, Endoscopic therapy with esophageal dilation
Device · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Sep 6, 2026, 10:00 AM EDT
Completed Phase 2 Interventional Results available

A Pivotal Subjective Sleep Study of a Nasal Dilator (Breathe Right Tan)

NCT03549117
View directory record Official record
Conditions
Congestion, Nasal
Interventions
Breathe Right Tan (small/medium) nasal strips, Placebo nasal strip
Device · Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Verona, New Jersey • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Sep 6, 2026, 10:00 AM EDT
Recruiting No phase listed Observational

Quantifying Radiation Induced Vaginal Stenosis

NCT05002751
View directory record Official record
Conditions
Vaginal Stricture, Vaginal Stenosis
Interventions
UCSD Vaginal Dilator Questionnaire, EORTC Sexual Health Questionnaire
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Sep 6, 2026, 10:00 AM EDT
Terminated Not applicable Interventional Results available

Esophageal Dysmotility - Prospective Study Evaluating Methods for Esophageal Dilation

NCT03604523
View directory record Official record
Conditions
Esophageal Dysmotility
Interventions
Dilation by Balloon, Dilation by Semi-rigid Savary
Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Sep 6, 2026, 10:00 AM EDT
Recruiting Not applicable Interventional

Ripening Approaches for Prompt Induction and Delivery - Sequential Versus Concurrent Dilapan-S and Misoprostol to Achieve Vaginal Delivery (RAPID-DS)

NCT07717502
View directory record Official record
Conditions
Nulliparous Women Who Scheduled for Labor Induction, Pregnancy
Interventions
Sequential Cervical Ripening, Inpatient Combined Cervical Ripening
Combination Product
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 6, 2026, 10:00 AM EDT
Completed No phase listed Observational

MIS MiLIF Versus Open

NCT00792129
View directory record Official record
Conditions
Chronic Low Back Pain, Leg Pain
Interventions
The Atavi System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 75 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
9
States / cities
La Jolla, California • San Diego, California • Port Charlotte, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2012 · Synced Sep 6, 2026, 10:00 AM EDT
Active, not recruiting No phase listed Observational

Registry of the Patient Experience for Carpal Tunnel Release

NCT06071468
View directory record Official record
Conditions
Carpal Tunnel Syndrome, CTS
Interventions
UltraGuideCTR (Device) with Ultrasound Guided Carpal Tunnel Release (CTR-US), Endocscopic CTR, Open CTR
Device · Procedure
Lead sponsor
Sonex Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Timeline
2024 – 2027
U.S. locations
33
States / cities
Foley, Alabama • Scottsdale, Arizona • Glastonbury, Connecticut + 30 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 6, 2026, 10:00 AM EDT
Recruiting Not applicable Interventional

Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy

NCT06059586
View directory record Official record
Conditions
Dyspareunia, Pelvic Pain, Sexual Dysfunction, Radiation Toxicity
Interventions
Pelvic health therapy, Dilator feasability
Behavioral · Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Avon, Indiana • Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 6, 2026, 10:00 AM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers

A Human Factors Study to Evaluate a Novel Intracanalicular Insertion Device in Healthy Subjects

NCT04945824
View directory record Official record
Conditions
Healthy
Interventions
Dexamethasone Ophthalmic, Dilator
Drug · Device
Lead sponsor
Ocular Therapeutix, Inc.
Industry
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Feb 5, 2023 · Synced Sep 6, 2026, 10:00 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cervical Preparation Before Dilation and Evacuation

NCT01751087
View directory record Official record
Conditions
Abortion, Induced
Interventions
Mifepristone, misoprostol, Osmotic dilators, placebo
Other · Drug · Device
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
7
States / cities
San Francisco, California • Chicago, Illinois • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Sep 6, 2026, 10:00 AM EDT