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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Distress Reduction Clear all
Completed Not applicable Interventional

Identifying Stress Urinary Incontinence in Women With Pelvic Organ Prolapse

NCT03005977
View directory record Official record
Conditions
Stress Urinary Incontinence, Pelvic Organ Prolapse
Interventions
Urodynamics
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Apr 6, 2022 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Increasing Help-Seeking in Military Service Members

NCT04043936
View directory record Official record
Conditions
Military Service Members at Elevated Suicide Risk
Interventions
Cognitive Bias Modification Intervention for Help-Seeking Stigma, Placebo Cognitive Bias Modification (CBM-Placebo), Self-Directed Psychoeducation
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Tallahassee, Florida • Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Sep 3, 2026, 3:14 AM EDT
Not yet recruiting Not applicable Interventional

Feasibility and Acceptability of Empowered Relief for American Indians With Pain During and After Cancer Treatment

NCT07742449
View directory record Official record
Conditions
Cancer, Pain, Pain Management, Chronic Pain, American Indian or Alaska Native
Interventions
Empowered Relief
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Not applicable Interventional Results available

Acceptance-based Group Intervention for Binge Eating

NCT01757847
View directory record Official record
Conditions
Binge-Eating Disorder
Interventions
Acceptance and Commitment Therapy (ACT), Brief MOVE-II control group intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2016 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Improving Flexibility With a Mindbody Approach

NCT01066325
View directory record Official record
Conditions
General Low Back Hip and Hamstring Flexibility
Interventions
Neuro Emotional Technique, Stretching Instruction
Behavioral · Other
Lead sponsor
Parker Research Institute
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use

NCT06366633
View directory record Official record
Conditions
Orthopedic Disorder, Nontraumatic Injury, Substance Use, Upper Extremity Problem
Interventions
Web-TIRELESS
Behavioral
Lead sponsor
Jafar Bakhshaie
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 3, 2026, 3:14 AM EDT
Terminated Phase 3 Interventional Results available

12 Week Safety Trial of Flibanserin in Depressed Women Taking an SSRI or SNRI With Decreased Sexual Desire and Distress

NCT01040208
View directory record Official record
Conditions
Sexual Dysfunctions, Psychological, Depression
Interventions
flibanserin 50 mg to 100 mg qhs, flibanserin 100 mg qhs, placebo 2 tablets qhs
Drug
Lead sponsor
Sprout Pharmaceuticals, Inc
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
42
States / cities
Costa Mesa, California • Fresno, California • National City, California + 36 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2016 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Distress in Phase 1 Trial Caregivers: The P1-CaLL Study

NCT03557515
View directory record Official record
Conditions
Caregiver Distress
Interventions
Stress Management and CBT, Stress Management and Metta-Meditation
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 99 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 25, 2021 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mobile Health and COVID-19

NCT05074693
View directory record Official record
Conditions
Anxiety Depression
Interventions
EASE app, INSIGHT (Control) App
Other
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
822 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Oklahoma City, Oklahoma • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 3, 2026, 3:14 AM EDT
Recruiting Not applicable Interventional

Brief Digitally-Enhanced Intervention for Reducing Alcohol Use During MOUD

NCT06718491
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Managing Physical Reactions to Overwhelming Emotions (IMPROVE), Health Education Training (HET)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 3, 2026, 3:14 AM EDT
Active, not recruiting Not applicable Interventional

A Study Comparing Mindfulness Apps to Decrease Anxiety in People With Lung Cancer

NCT06008574
View directory record Official record
Conditions
Lung Cancer
Interventions
AmDTx-PCSP, AmDTx-2048, Questionnaires
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Not applicable Interventional Results available

Nonpharmacologic Reduction of Periprocedural Distress and Drug Use

NCT03328208
View directory record Official record
Conditions
Dental Anxiety, Dental Pain, Drug Use, Opioid Use
Interventions
Comfort Talk® app, White Noise app
Other
Lead sponsor
Hypnalgesics, LLC
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Brookline, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 29, 2021 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Cognitive Rehabilitation and Exposure-based Class for Compulsive Hoarding

NCT02306174
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Cognitive Rehabilitation and Exposure-based Class for Compulsive Hoarding
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 85 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 3, 2026, 3:14 AM EDT
Not yet recruiting Not applicable Interventional

Group Emotion-Focused Behavioral Intervention for Diabetes Distress/A1c in T2D.

NCT06912737
View directory record Official record
Conditions
T2DM (Type 2 Diabetes Mellitus)
Interventions
Group Emotion Focused Behavioral Intervention (G-EFBI), Group - With Every Heartbeat is Life (G-WEHL)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mobile Web-based Behavioral Intervention for Improving Caregiver Well-being

NCT03506945
View directory record Official record
Conditions
Depressive Symptoms, Stress, Psychological
Interventions
mPEP, Bibliotherapy
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years and older
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Phase 1 Interventional

Improving Quality-of-life and Depressive Symptoms of Combat Veterans Via Internet-based Intervention

NCT01231711
View directory record Official record
Conditions
Depression, Post-Traumatic Stress Disorder, Functional Status
Interventions
Vets Prevail
Behavioral
Lead sponsor
Prevail Health Solutions, LLC
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 31, 2010 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Evaluation of Regulation Focused Psychotherapy for Children

NCT03594253
View directory record Official record
Conditions
Oppositional Defiant Disorder, Oppositional Defiant Disorder in Children
Interventions
Regulation Focused Psychotherapy for Children
Behavioral
Lead sponsor
Yeshiva University
Other
Eligibility
5 Years to 12 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 29, 2023 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Music in Reducing Distress in Participants with Cancer During Chemotherapy Treatment

NCT03683420
View directory record Official record
Conditions
Caregiver, Malignant Neoplasm
Interventions
Music Therapy
Behavioral
Lead sponsor
Barbara Ann Karmanos Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Administration of Intravenous Vitamin C in Novel Coronavirus Infection (COVID-19) and Decreased Oxygenation

NCT04357782
View directory record Official record
Conditions
COVID-19, Hypoxia
Interventions
L-ascorbic acid
Drug
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 24, 2022 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fostering Resilience to Psychosocial and HIV Risk in Indian MSM

NCT02556294
View directory record Official record
Conditions
HIV Infection, Sexual Behavior, Health Behavior
Interventions
Self-acceptance based intervention, HIV/STI counseling and testing
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
608 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2019 · Synced Sep 3, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Cognitive Behavioral Therapy for Adolescents With Bulimia Nervosa and Higher Weight (Online Treatment Study)

NCT05770947
View directory record Official record
Conditions
Bulimia Nervosa, Overweight or Obesity
Interventions
Cognitive Behavioral Therapy, Mindfulness
Behavioral
Lead sponsor
Yale University
Other
Eligibility
12 Years to 19 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 3, 2026, 3:14 AM EDT
Terminated Not applicable Interventional Results available

Bringing Exposure Therapy to Real-Life Context With Augmented Reality

NCT03649347
View directory record Official record
Conditions
Phobias Snakes, Phobias Spiders
Interventions
Augmented reality exposure therapy
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Sep 3, 2026, 3:14 AM EDT
Recruiting Not applicable Interventional

Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's

NCT05748613
View directory record Official record
Conditions
Anxiety, Mild Cognitive Impairment, Alzheimer Disease, Dementia
Interventions
Computerized Anxiety Sensitivity Treatment, Health Education Control
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
60 Years and older
Enrollment
388 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
3
States / cities
Tallahassee, Florida • Athens, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 3, 2026, 3:14 AM EDT
Recruiting Not applicable Interventional

SMART Embedded Intervention for Military Postsurgical Engagement Readiness

NCT05050409
View directory record Official record
Conditions
Knee Pain Chronic
Interventions
Brief mindfulness, Mindfulness-Oriented Recovery Enhancement (MORE), Standard care
Behavioral · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Sep 3, 2026, 3:14 AM EDT