- Conditions
- Smallpox
- Interventions
- Dryvax
- Biological
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- Not listed
- Enrollment
- 90 participants
- Timeline
- 2004
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
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Showing 1–24
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Smallpox
- Interventions
- IMVAMUNE®
- Biological
- Lead sponsor
- Bavarian Nordic
- Industry
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 87 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 10
- States / cities
- Birmingham, Alabama • Little Rock, Arkansas • San Francisco, California + 7 more
- Conditions
- Yellow Fever, Yellow Fever Immunisation
- Interventions
- ISA-720, MVA Smallpox Vaccine, MVA-BN Yellow Fever Vaccine, Placebo, YF Vax 17D Strain
- Drug · Biological · Other
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 92 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2018
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa • St Louis, Missouri
- Conditions
- Smallpox
- Interventions
- Not listed
- Lead sponsor
- Emergent BioSolutions
- Industry
- Eligibility
- 17 Years and older
- Enrollment
- 5,001 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Alexandria, Virginia
- Conditions
- Smallpox
- Interventions
- MVA Smallpox Vaccine, Placebo
- Biological · Other
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 38 Years
- Enrollment
- 91 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2011
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa • St Louis, Missouri
- Conditions
- Myocarditis, Pericarditis
- Interventions
- Not listed
- Lead sponsor
- Emergent BioSolutions
- Industry
- Eligibility
- 17 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2019
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Smallpox
- Interventions
- ACAM3000 MVA Vaccine
- Biological
- Lead sponsor
- Sanofi Pasteur, a Sanofi Company
- Industry
- Eligibility
- 18 Years to 31 Years
- Enrollment
- 110 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2006
- U.S. locations
- 2
- States / cities
- Lenexa, Kansas • Lexington, Kentucky
- Conditions
- Healthy
- Interventions
- Modified Vaccinia Virus Ankara TBC-MVA
- Drug
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- Not listed
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003 – 2006
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Vaccinia, Virus Diseases
- Interventions
- JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) suspension for subcutaneous injection, Phlebotomy, Research bronchoscopy, Skin punch biopsy, Bone marrow aspiration
- Biological · Procedure
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Smallpox
- Interventions
- MVA Smallpox Vaccine, Placebo, Live vaccinia virus vaccine
- Biological · Other
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 38 Years
- Enrollment
- 72 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2008
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Smallpox
- Interventions
- Live vaccinia virus vaccine, MVA Smallpox Vaccine, Placebo
- Biological · Other
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 32 Years
- Enrollment
- 91 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Smallpox
- Interventions
- ACAM2000 Smallpox Vaccine, Vaccinia virus (calf lymph) smallpox vaccine: Dryvax®
- Biological
- Lead sponsor
- Emergent BioSolutions
- Industry
- Eligibility
- 28 Years and older
- Enrollment
- 357 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003
- U.S. locations
- 3
- States / cities
- Lenexa, Kansas • Springfield, Missouri • Pawtucket, Rhode Island
- Conditions
- Smallpox
- Interventions
- FD MVA-BN
- Biological
- Lead sponsor
- Bavarian Nordic
- Industry
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 1,129 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 12
- States / cities
- Birmingham, Alabama • Melbourne, Florida • Peoria, Illinois + 8 more
- Conditions
- Smallpox Vaccine Adverse Reaction
- Interventions
- ACAM2000
- Biological
- Lead sponsor
- Emergent BioSolutions
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Altamonte Springs, Florida
- Conditions
- Smallpox
- Interventions
- Live vaccinia virus vaccine, MVA Smallpox Vaccine, Placebo
- Biological · Other
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 38 Years
- Enrollment
- 226 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2009
- U.S. locations
- 7
- States / cities
- Iowa City, Iowa • Baltimore, Maryland • St Louis, Missouri + 4 more
- Conditions
- Smallpox
- Interventions
- Vaccinia virus: ACAM2000 smallpox vaccine, vaccinia virus (calf lymph): Dryvax
- Biological
- Lead sponsor
- Emergent BioSolutions
- Industry
- Eligibility
- 18 Years to 29 Years
- Enrollment
- 353 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003
- U.S. locations
- 4
- States / cities
- Orlando, Florida • Lenexa, Kansas • Springfield, Missouri + 1 more
- Conditions
- HIV Infections
- Interventions
- IMVAMUNE (MVA-BN)
- Biological
- Lead sponsor
- Bavarian Nordic
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 151 participants
- Timeline
- Started 2005
- U.S. locations
- 5
- States / cities
- Indianapolis, Indiana • Lexington, Kentucky • St Louis, Missouri + 2 more
- Conditions
- Smallpox
- Interventions
- Cell-Cultured Smallpox Vaccine compared to Dryvax®
- Biological
- Lead sponsor
- DynPort Vaccine Company LLC, A GDIT Company
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 350 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2002 – 2003
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Smallpox
- Interventions
- MVA Smallpox Vaccine
- Biological
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 38 Years
- Enrollment
- 523 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2011
- U.S. locations
- 8
- States / cities
- Decatur, Georgia • Iowa City, Iowa • Baltimore, Maryland + 4 more
- Conditions
- Smallpox
- Interventions
- MVA Smallpox Vaccine
- Biological
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 435 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2015
- U.S. locations
- 6
- States / cities
- Decatur, Georgia • Iowa City, Iowa • Baltimore, Maryland + 3 more
- Conditions
- Smallpox, Atopic Dermatitis
- Interventions
- MVA (smallpox vaccine)
- Biological
- Lead sponsor
- Sanofi Pasteur, a Sanofi Company
- Industry
- Eligibility
- 18 Years to 35 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2007
- U.S. locations
- 3
- States / cities
- Albuquerque, New Mexico • Portland, Oregon • Austin, Texas
- Conditions
- Smallpox
- Interventions
- Tecovirimat, Smallpox and Mpox Vaccine, Placebo
- Drug · Other
- Lead sponsor
- SIGA Technologies
- Industry
- Eligibility
- 18 Years to 42 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2027
- U.S. locations
- 2
- States / cities
- Omaha, Nebraska • Columbus, Ohio
- Conditions
- Smallpox
- Interventions
- Wetvax (APSV)
- Biological
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 32 Years
- Enrollment
- 330 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2002
- U.S. locations
- 4
- States / cities
- Oakland, California • Iowa City, Iowa • Nashville, Tennessee + 1 more
- Conditions
- Atopic Dermatitis
- Interventions
- IMVAMUNE
- Biological
- Lead sponsor
- Bavarian Nordic
- Industry
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 632 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2010
- U.S. locations
- 15
- States / cities
- Tucson, Arizona • Hot Springs, Arkansas • Garden Grove, California + 11 more