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ClinicalTrials.gov public records Last synced Oct 21, 2026, 9:50 AM EDT

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Showing 1–24 of 66 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: ED-HEART Clear all
Completed Phase 4 Interventional Accepts healthy volunteers

Improving the Management of Acute Coronary Syndromes in the Emergency Department

NCT01563250
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Point of Care testing
Device
Lead sponsor
Integrated Medical Research LLC
Other
Eligibility
35 Years and older
Enrollment
705 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 4, 2013 · Synced Oct 21, 2026, 9:50 AM EDT
Completed No phase listed Observational

Magnetocardiography Using a Novel Analysis System (Cardioflux) in the Evaluation of Emergency Department Observation Unit Chest Pain Patients

NCT03255772
View directory record Official record
Conditions
Acute Coronary Syndrome, Myocardial Infarction
Interventions
Magnetocardiography
Diagnostic Test
Lead sponsor
Genetesis Inc.
Industry
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 28, 2022 · Synced Oct 21, 2026, 9:50 AM EDT
Completed Not applicable Interventional Results available

Computed Tomography Coronary Angiogram (CTCA) Versus Traditional Care in Emergency Department Assessment of Potential Acute Coronary Syndromes (ACS)

NCT00933400
View directory record Official record
Conditions
Chest Pain, Acute Coronary Syndrome, Acute Myocardial Infarction, Coronary Artery Disease
Interventions
CT Coronary Angiography (CTCA), Traditional Strategy
Diagnostic Test · Procedure
Lead sponsor
American College of Radiology
Other
Eligibility
30 Years and older
Enrollment
1,392 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
5
States / cities
Winston-Salem, North Carolina • Hershey, Pennsylvania • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 6, 2024 · Synced Oct 21, 2026, 9:50 AM EDT
Completed No phase listed Observational

Abbott i-STAT High Sensitivity Troponin I Study

NCT05629572
View directory record Official record
Conditions
Myocardial Infarction
Interventions
i-STAT hs-TnI Cartridge Testing on i-STAT 1 and i-STAT Alinity
Diagnostic Test
Lead sponsor
Abbott Point of Care
Industry
Eligibility
18 Years and older
Enrollment
3,697 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
28
States / cities
Chandler, Arizona • San Francisco, California • Stanford, California + 25 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 21, 2026, 9:50 AM EDT
Completed No phase listed Observational

5th Generation cTnT in ED ACS

NCT03590535
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
4th Gen cTnT, 5th Gen cTnT
Diagnostic Test
Lead sponsor
Columbia University
Other
Eligibility
19 Years and older
Enrollment
1,949 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2022 · Synced Oct 21, 2026, 9:50 AM EDT
Completed No phase listed Observational

Acute Chest Pain Imaging in the ED With the Combine CCTA and CT Perfusion

NCT02538861
View directory record Official record
Conditions
Chest Pain
Interventions
SPECT Imaging Test at Baptist hospital, CT Angiography and CT myocardial perfusion at West Kendall Baptist Hospital, SPECT Imaging Test at West Kendall Baptist Hospital
Diagnostic Test
Lead sponsor
Baptist Health South Florida
Other
Eligibility
35 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 20, 2022 · Synced Oct 21, 2026, 9:50 AM EDT
Completed No phase listed Observational

Identifying High- and Low-Risk Heart Failure Patients in the Emergency Department (The Stratify Study)

NCT00508638
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
1,033 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 19, 2017 · Synced Oct 21, 2026, 9:50 AM EDT
Enrolling by invitation No phase listed Observational

A Study to Assess the Accuracy of Magnetocardiography (MCG) to Diagnose True Ischemia in Patients With Chest Pain in the ED

NCT05809648
View directory record Official record
Conditions
Chest Pain, Emergency Medicine
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 21, 2026, 9:50 AM EDT
Terminated Not applicable Interventional

Assessing Outcomes in ED Patients With RV Failure

NCT03073629
View directory record Official record
Conditions
Right Heart Failure
Interventions
Clinical Pathway
Diagnostic Test
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 15, 2022 · Synced Oct 21, 2026, 9:50 AM EDT
Terminated Phase 4 Interventional

BNP Therapy Observation Unit Outcomes STudy (BOOST)

NCT00453453
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Nesiritide
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 9, 2015 · Synced Oct 21, 2026, 9:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PREVENT - Prospective Rhythm Event Surveillance in the ER With NetGuard

NCT00750958
View directory record Official record
Conditions
Cardiac Event
Interventions
NetGuard Automated Clinician Alert System
Procedure
Lead sponsor
Datascope Patient Monitoring
Industry
Eligibility
18 Years and older
Enrollment
287 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 11, 2008 · Synced Oct 21, 2026, 9:50 AM EDT
Completed Not applicable Interventional

Point-of-care Ultrasound and Treatment Disparities for Left Ventricular Hypertrophy

NCT05730309
View directory record Official record
Conditions
Left Ventricular Hypertrophy
Interventions
Customized discharge and expedited referral instructions
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 21, 2026, 9:50 AM EDT
Not listed No phase listed Observational

Paced Electrocardiogram Requiring Fast Emergent Coronary Therapy (PERFECT) Study

NCT02765477
View directory record Official record
Conditions
Acute Myocardial Infarction
Interventions
Not listed
Lead sponsor
Hennepin County Medical Center, Minneapolis
Other
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 1, 2016 · Synced Oct 21, 2026, 9:50 AM EDT
Completed No phase listed Observational

Diagnosis and Treatment of ACS in the ED: The Impact of Rapid Bedside cTnI Testing on Outcomes

NCT00222352
View directory record Official record
Conditions
Angina, Unstable
Interventions
Point of Care cTnL testing
Diagnostic Test
Lead sponsor
University of Cincinnati
Other
Eligibility
21 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
4
States / cities
Stanford, California • Royal Oak, Michigan • Cincinnati, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Oct 21, 2026, 9:50 AM EDT
Completed Not applicable Interventional Results available

An Enhanced Home-Based Telemedicine Program Using Remote Examination Devices for Children With Medical Complexity

NCT05408143
View directory record Official record
Conditions
Chronic Diseases in Children
Interventions
Comprehensive care (CC) program, Enhanced telemedicine (ETM)
Other · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Up to 18 Years
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 21, 2026, 9:50 AM EDT
Completed Phase 3 Interventional Results available

Tele-Electrocardiography in Emergency Cardiac Care

NCT00075088
View directory record Official record
Conditions
Myocardial Infarction, Chest Pain
Interventions
Electrocardiogram (ECG) Intervention, Routine Clinical Practice
Device · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
794 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2015 · Synced Oct 21, 2026, 9:50 AM EDT
Withdrawn Phase 2 Interventional

N2O for Acute Suicidality and Depression in the ED

NCT05710887
View directory record Official record
Conditions
Suicidal Ideation, Major Depressive Disorder, Treatment Resistant Depression
Interventions
Nitrous oxide gas for inhalation, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 21, 2026, 9:50 AM EDT
Completed No phase listed Observational

Near Infrared Spectroscopy (St02)

NCT01062685
View directory record Official record
Conditions
Septic Shock
Interventions
Near-infrared spectroscopy assessment
Diagnostic Test
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 29, 2024 · Synced Oct 21, 2026, 9:50 AM EDT
Recruiting Not applicable Interventional

Capitalizing on AI to CapTure Undiagnosed Structural Heart Disease

NCT07843004
View directory record Official record
Conditions
Structural Heart Abnormality, Valve Heart Disease, Heart Diseases, Cardiovascular Diseases
Interventions
EHR Alert
Device
Lead sponsor
Pierre Elias
Other
Eligibility
40 Years and older
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 21, 2026, 9:50 AM EDT
Recruiting Not applicable Interventional

CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)

NCT05897632
View directory record Official record
Conditions
Chest Pain
Interventions
Outpatient Evaluation, Hospitalization Evaluation
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older
Enrollment
502 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
3
States / cities
Detroit, Michigan • Charlotte, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 21, 2026, 9:50 AM EDT
Terminated Not applicable Interventional Results available

Advanced Reperfusion Strategies for Refractory Cardiac Arrest

NCT03880565
View directory record Official record
Conditions
Cardiac Arrest, Extracorporeal Membrane Oxygenation Complication, Ventricular Fibrillation, Pulseless Ventricular Tachycardia, Out-Of-Hospital Cardiac Arrest
Interventions
Early Extracorporeal Membrane Oxygenation (ECMO) Facilitated Resuscitation, Standard Advanced Cardiac Life Support (ACLS) Resuscitation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Oct 21, 2026, 9:50 AM EDT
Completed No phase listed Observational Results available

Verification of Prediction Algorithm

NCT02863666
View directory record Official record
Conditions
Shortness of Breath Episode, Tachycardia, Bradycardia, Difficulty Breathing
Interventions
Not listed
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
673 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Birmingham, Alabama • Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Oct 21, 2026, 9:50 AM EDT
Active, not recruiting No phase listed Observational

Assessing Chest Pain Using Point-of-Care High-Sensitivity Troponin I in the Emergency Department

NCT06899776
View directory record Official record
Conditions
ACS (Acute Coronary Syndrome)
Interventions
Abbott i-STAT point of care (POC) device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
3
States / cities
Charlotte, North Carolina • High Point, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 21, 2026, 9:50 AM EDT
Completed No phase listed Observational

Hormones and Sexual Function Predict Outcomes in Revascularized Men With Diabetes

NCT01190904
View directory record Official record
Conditions
Androgen Deficiency, AD, Erectile Dysfunction, ED, Diabetes Mellitus, Coronary Artery Disease, Coronary Revascularization
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 75 Years · Male only
Enrollment
568 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
5
States / cities
Guttenberg, New Jersey • Elmhurst, New York • Mineola, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2016 · Synced Oct 21, 2026, 9:50 AM EDT