- Conditions
- Symptomatic Aortic Stenosis, Aortic Valve Stenosis, Aortic Valve Replacement
- Interventions
- Medtronic Evolut PRO, Evolut PRO+ or Evolut FX (where commercially available) TAV Systems, Edwards SAPIEN 3 or SAPIEN 3 Ultra THV Systems
- Device
- Lead sponsor
- Medtronic Cardiovascular
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,103 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2027
- U.S. locations
- 61
- States / cities
- La Jolla, California • Los Angeles, California • San Francisco, California + 47 more
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- Conditions
- Aortic Stenosis, Aortic Stenosis, Severe
- Interventions
- Edwards SAPIEN 3/SAPIEN 3 Ultra THV
- Device
- Lead sponsor
- Edwards Lifesciences
- Industry
- Eligibility
- Not listed
- Enrollment
- 125 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2038
- U.S. locations
- 50
- States / cities
- Phoenix, Arizona • Los Angeles, California • Sacramento, California + 43 more
- Conditions
- Heart Diseases, Aortic Stenosis, Severe
- Interventions
- Edwards SAPIEN 3 / SAPIEN 3 Ultra THV
- Device
- Lead sponsor
- Edwards Lifesciences
- Industry
- Eligibility
- 65 Years and older
- Enrollment
- 901 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2032
- U.S. locations
- 74
- States / cities
- Phoenix, Arizona • Burlingame, California • Los Angeles, California + 62 more