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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Esophageal probe Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Understanding the Pathophysiology and Effects of Diaphragmatic Breathing in Upright Gastroesophageal Reflux

NCT02972047
View directory record Official record
Conditions
GERD
Interventions
Diaphragmatic Breathing, Sham Comparator
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 3, 2020 · Synced Sep 13, 2026, 9:01 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Esophageal and Gastric Registry and Biorepository

NCT05180253
View directory record Official record
Conditions
Gastro Esophageal Reflux
Interventions
Esophageal studies
Diagnostic Test
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 13, 2026, 9:01 PM EDT
Withdrawn Not applicable Interventional

Intraoperative Goal-directed Fluid Management

NCT00554944
View directory record Official record
Conditions
Obesity, Abdominal Surgery, Hysterectomy, Genital Prolapse
Interventions
Esophageal probe
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 22, 2017 · Synced Sep 13, 2026, 9:01 PM EDT
Terminated No phase listed Observational

EndoFLIP Use in Upper GI Tract Stenosis

NCT02354716
View directory record Official record
Conditions
Esophageal Stricture, Eosinophilic Esophagitis, Zenkers Diverticulum, Schatzki Ring
Interventions
EndoFLIP
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 11, 2019 · Synced Sep 13, 2026, 9:01 PM EDT
Recruiting Phase 2 Interventional

Effectiveness and Performance of an Optical Biopsy Technology for Esophageal Cancer in Brazil and the United States

NCT06435286
View directory record Official record
Conditions
Suspected or Known Squamous Cell Neoplasia, Prior History of Squamous Cell Dysplasia and /or Neoplasia
Interventions
Proflavine Hemisulfate, Artificial Intelligence Mobile High-Resolution Microendoscope
Drug · Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 13, 2026, 9:01 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

High Resolution Optical Imaging of the Esophagus Using the NvisionVLE™ Imaging System

NCT02031900
View directory record Official record
Conditions
Undergoing Esophagogastroduodenoscopy (EGD)
Interventions
NvisionVLE Imaging System: NvisionVLE Imaging Console, NvisionVLE Optical Probe and Inflation Accessory Kit
Device
Lead sponsor
NinePoint Medical
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 25, 2014 · Synced Sep 13, 2026, 9:01 PM EDT
Suspended No phase listed Observational Accepts healthy volunteers

Morphological Markers of Gastroesophageal Reflux Disease (GERD)

NCT01921686
View directory record Official record
Conditions
Eosinophilic Esophagitis, Gastroesophageal Reflux Disease
Interventions
Sample collection and Questionnaire
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
8 Years to 18 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 13, 2026, 9:01 PM EDT
Completed Not applicable Interventional

Esophagus Deviation During Radiofrequency Ablation of Atrial Fibrillation - EASY AF STUDY

NCT04659213
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
esolution catheter
Device
Lead sponsor
S4 Medical
Industry
Eligibility
22 Years to 80 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 30, 2022 · Synced Sep 13, 2026, 9:01 PM EDT
Completed Not applicable Interventional Results available

Esophageal Temperature Management During Cryo AF Ablation (EnsoETM)

NCT04079634
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Esophageal warming, Control
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 15, 2023 · Synced Sep 13, 2026, 9:01 PM EDT
Completed Not applicable Interventional Results available

Esophageal Cooling for AF Ablation

NCT03691571
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Esophageal Cooling, Control
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 4, 2022 · Synced Sep 13, 2026, 9:01 PM EDT
Recruiting Phase 4 Interventional

Comprehensive Esophageal Diagnostics Study

NCT04641702
View directory record Official record
Conditions
Achalasia
Interventions
Atropine challenge, Esophageal muscle biopsy
Drug · Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 13, 2026, 9:01 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Fundoplication in Laparoscopic PEH Repair Based on FLIP

NCT05807763
View directory record Official record
Conditions
Paraesophageal Hernia
Interventions
Laparoscopic paraesophageal hernia repair without fundoplication
Procedure
Lead sponsor
The Foundation for Surgical Innovation and Education
Other
Eligibility
18 Years and older
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
2
States / cities
Evanston, Illinois • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Sep 13, 2026, 9:01 PM EDT
Not yet recruiting Not applicable Interventional

Non-invasive Temperature Monitoring in Pediatric Intensive Care Patients Requiring Targeted Temperature Management: Evaluation of Temple Touch Pro

NCT07507396
View directory record Official record
Conditions
Temperature Monitoring
Interventions
Temple Touch Pro
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
0 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 13, 2026, 9:01 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

[Impedance Measurement for Non-Erosive Reflux Disease

NCT02997527
View directory record Official record
Conditions
GERD, Healthy
Interventions
Intraluminal Impedance
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 12, 2018 · Synced Sep 13, 2026, 9:01 PM EDT
Terminated Not applicable Interventional Results available

Providing Optimal PEEP During Mechanical Ventilation for Obese Patients Using Esophageal Balloon

NCT03951064
View directory record Official record
Conditions
Obesity, Morbid, Ventilator-Induced Lung Injury, Respiratory Failure
Interventions
Esophageal balloon, Intervention Spontaneous Breathing Trial (SBT) and Extubation, Control Spontaneous Breathing Trial and Extubation, Intervention Weaning after Tracheostomy, Control Weaning after Tracheostomy
Device · Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Sep 13, 2026, 9:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

a/LCI-OCT Pilot in Esophagus

NCT04392167
View directory record Official record
Conditions
Barrett Esophagus
Interventions
a/LCI-OCT imaging probe, esophageal biopsy
Device · Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years to 80 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Sep 13, 2026, 9:01 PM EDT
Completed Phase 3 Interventional

Whole-Body Cooling for Birth Asphyxia in Term Infants

NCT00005772
View directory record Official record
Conditions
Infant, Newborn, Hypoxia-Ischemia, Brain
Interventions
Induced hypothermia, Control
Device
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 6 Hours
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2010
U.S. locations
16
States / cities
Birmingham, Alabama • Palo Alto, California • New Haven, Connecticut + 13 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Sep 13, 2026, 9:01 PM EDT
Completed Not applicable Interventional

Pilot Study of Physiological Effect of High-Flow Nasal Cannula on Respiratory Pattern and Work of Breathing

NCT02514798
View directory record Official record
Conditions
COPD
Interventions
Esophageal and gastric balloons, Respiratory Inductance Plethysmography (RIP) system, Sentec transcutaneous monitoring system, High-flow humidified nasal oxygen delivery system, CPAP (Positive Control)
Other · Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Sep 13, 2026, 9:01 PM EDT
Completed Not applicable Interventional

Trial With Deltex Cardio in Elective Bowel Resection Patients

NCT01244685
View directory record Official record
Conditions
1 Fluid Management
Interventions
Deltex CardioQ Probe
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Oct 4, 2012 · Synced Sep 13, 2026, 9:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Dx-pH Probe in Diagnosing Extra-esophageal Reflux Disease

NCT00388453
View directory record Official record
Conditions
GERD, Larynx Disease
Interventions
Dx-pH Probe, Manometry
Device · Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Sep 13, 2026, 9:01 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the CIRCA Monitoring System in Prevention of Esophageal Lesions Following RFCA

NCT02467166
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Circa™ Probe
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 1, 2021 · Synced Sep 13, 2026, 9:01 PM EDT
Terminated Not applicable Interventional Results available

Safety of Optimal PEEP in NSICU Patients

NCT03862027
View directory record Official record
Conditions
Respiratory Failure, Intracranial Hypertension
Interventions
Esophageal Balloon catheter
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
Not listed
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2021 · Synced Sep 13, 2026, 9:01 PM EDT
Completed Not applicable Interventional

Esophageal Protection Study: A Multicenter Study

NCT04577859
View directory record Official record
Conditions
AF - Atrial Fibrillation, Complication, Atrio-Esophageal Fistula
Interventions
ensoETM. Esophageal cooling during AF ablation, Esophageal temperature monitoring probe
Device
Lead sponsor
Advanced Cooling Therapy LLC, d/b/a Attune Medical
Industry
Eligibility
18 Years to 85 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
5
States / cities
Naples, Florida • Overland Park, Kansas • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 13, 2026, 9:01 PM EDT
Completed Early Phase 1 Interventional

The Effect of Sucralfate Slurry in Patients With Eosinophilic Esophagitis

NCT02353078
View directory record Official record
Conditions
Eosinophilic Esophagitis
Interventions
Sucralfate, Intraluminal Impedance, Intraluminal Impedance
Drug · Procedure · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 10, 2017 · Synced Sep 13, 2026, 9:01 PM EDT