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Showing 1–24 of 542 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Exercise and Dietary Weight Loss Clear all
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Healthy Eating and Active Living Taught at Home (HEALTH) Dissemination & Implementation (D&I)

NCT03758638
View directory record Official record
Conditions
Obesity
Interventions
Healthy Eating & Active Living Taught at Home, Usual Care
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
620 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional Results available

Dissemination of the Look Ahead Weight Management Treatment in the Military

NCT02063178
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Phone-based sessions (28 total) on a structured schedule, Phone-based sessions upon request, Weight self-monitoring, Dietary and physical activity self-monitoring, Scheduled tailored interventionist feedback, Dietary goals, Meal replacements, Physical activity goals, Toolbox, Challenges, Tailored interventionist feedback upon request
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 27, 2019 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimal Timing of Exercise Initiation Within a Lifestyle Weight Loss Program

NCT01985568
View directory record Official record
Conditions
Obesity
Interventions
Sequential BT, Standard BT
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional

Women's Health Project for Women Wanting to Lose Weight

NCT01671397
View directory record Official record
Conditions
Obesity
Interventions
Diet and exercise counseling, Diet, exercise, sleep hygiene counseling
Behavioral
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2014 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Phase 4 Interventional

Effects of Glucosamine and Chondroitin Supplementation in Women With Knee Osteoarthritis Participating in an Exercise and Weight Loss Program

NCT01271218
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Diet, Exercise
Other
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Jan 5, 2011 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Lean Living Study

NCT02501889
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Walnut-rich weight loss diet, Standard weight loss diet
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 25, 2017 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional Results available

Changing Lifestyles for Better Health

NCT00848757
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Intensive Lifestyle Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Sep 25, 2026, 10:55 PM EDT
Recruiting Phase 3 Interventional

AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

NCT07509307
View directory record Official record
Conditions
Obesity, Overweight, Osteoarthritis, Knee
Interventions
NNC0487-0111, Placebo (matched to NNC0487-0111)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
19
States / cities
Escondido, California • Lancaster, California • Palm Springs, California + 14 more
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Personalized Diet Study to Reduce Glycemic Exposure

NCT03336411
View directory record Official record
Conditions
Pre-diabetes, Overweight and Obesity
Interventions
mHealth, Personalized mHealth
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

mHealth Intervention for Older Adults

NCT03398590
View directory record Official record
Conditions
Type2 Diabetes, Obesity
Interventions
self-regulation theory-based mHealth behavior intervention
Behavioral
Lead sponsor
Boston College
Other
Eligibility
65 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2018 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Examining Cooking as a Health Behavior

NCT03783962
View directory record Official record
Conditions
Obesity
Interventions
Active Intervention - Cooking, Demonstrations - Cooking
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated May 16, 2021 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Personalized Telehealth Intervention for Health and Weight Loss in Postpartum Women

NCT01751230
View directory record Official record
Conditions
Postpartum Weight Retention
Interventions
WIC E-Moms
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 23, 2021 · Synced Sep 25, 2026, 10:55 PM EDT
Not listed Not applicable Interventional

The ReNEW Study: Maestro® New Enrollment Post-Approval Study Protocol

NCT03145636
View directory record Official record
Conditions
Obesity, Morbid
Interventions
vBloc Maestro Rechargeable System, vBloc Achieve Weight Management Program, Control Weight Management (CWM) program
Device · Other
Lead sponsor
ReShape Lifesciences
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
2
States / cities
Scottsdale, Arizona • Mineola, New York
Source: ClinicalTrials.gov public record
Updated May 21, 2019 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional

Weight Management Demonstration Project: HEALTH

NCT01307280
View directory record Official record
Conditions
Weight Loss
Interventions
RCT1, RCT2, RCT3
Behavioral
Lead sponsor
RTI International
Other
Eligibility
18 Years to 64 Years
Enrollment
2,395 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
3
States / cities
Swansea, Illinois • Research Triangle Park, North Carolina • Fairborn, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 25, 2012 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nutrigenomics: Personalizing Weight Loss for Obese Veterans

NCT01859403
View directory record Official record
Conditions
Obesity
Interventions
Personalized Genomics, Usual Care
Genetic
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Effect of Weight Loss and Exercise on Liver and Muscle Fat in Obese Elderly

NCT00779207
View directory record Official record
Conditions
Obesity
Interventions
weight loss and exercise, weight loss
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 23, 2008 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Partners in Health: A Couples-based Approach to Obesity Prevention

NCT02205281
View directory record Official record
Conditions
Obesity
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
California Polytechnic State University-San Luis Obispo
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
San Luis Obispo, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2020 · Synced Sep 25, 2026, 10:55 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Blood Glucose Differences Between Left Arm and Right Arm Using a Continuous Glucose Monitor

NCT04102657
View directory record Official record
Conditions
Diabetes
Interventions
Intermittent Fasting, Free-Living Diet, Left Arm Exercise, Right Arm Exercise
Other
Lead sponsor
University of the Pacific
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Stockton, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Mobile Lifestyle Intervention for Food and Exercise Study

NCT05176847
View directory record Official record
Conditions
Overweight and Obesity, Type2 Diabetes
Interventions
Podcasts and tips of the day (within app), mLIFE app (self-regulation features), mLIFE app (social support features), standard mLIFE app (social support features)
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
243 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Phase 4 Interventional Results available

Weight Loss Aid in an Exposed Population

NCT03582722
View directory record Official record
Conditions
Polybrominated Biphenyl Poisoning
Interventions
Orlistat, Placebo capsule, Multivitamin
Drug · Dietary Supplement
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Engaging Self-regulation Targets to Improve Mood and Weight and Understand Mechanism in Depressed and Obese Adults

NCT03841682
View directory record Official record
Conditions
Obesity, Depression
Interventions
I-CARE2
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 20, 2021 · Synced Sep 25, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men

NCT04186260
View directory record Official record
Conditions
NAFLD
Interventions
NAFLD-specific weight loss intervention, Wait-list control
Behavioral · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Sep 25, 2026, 10:55 PM EDT
Not listed Not applicable Interventional

Online Obesity Treatment in Primary Care (Rhode Island, USA)

NCT03488212
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Training to Identify Eligible Patients and Direct them to Online Obesity Treatment Program, Training to Motivate and Support Patients' Weight Loss, Online Behavioral Weight Loss Intervention, Control Intervention for Weight Loss Maintenance and Weight Gain Prevention, Monthly Lessons and Feedback Intervention for Weight Loss Maintenance and Weight Gain Prevention, Refresher Courses for Weight Loss Maintenance and Weight Gain Prevention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 19, 2020 · Synced Sep 25, 2026, 10:55 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Modifying Obesogenic Homes: Impact on Weight Maintenance

NCT00200330
View directory record Official record
Conditions
Obesity
Interventions
Behavioral weight loss treatment, Behavioral and home environment weight loss treatment
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 17, 2007 · Synced Sep 25, 2026, 10:55 PM EDT