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ClinicalTrials.gov public records Last synced Oct 14, 2026, 5:14 PM EDT

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Showing 361–384 of 543 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Exercise and Dietary Weight Loss Clear all
Active, not recruiting Not applicable Interventional

Expanding Delivery of an Evidence-based Weight-loss Intervention to Enhance Access and Reach Underserved Groups After TBI

NCT05699772
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Telehealth-delivered Group Lifestyle Balance for people with TBI (tGLB-TBI), Brain Health Group (BHG)
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Not applicable Interventional

A Remote Delivered Lifestyle Therapeutics Program

NCT04201028
View directory record Official record
Conditions
Body Weight Changes, Weight Loss, Healthy Diet, Obesity
Interventions
Video Conferencing Health Coaching with devices, Video Conferencing Health Coaching with no devices
Behavioral
Lead sponsor
Coastal Carolina University
Other
Eligibility
20 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Oct 14, 2026, 5:14 PM EDT
Active, not recruiting Not applicable Interventional

Program for Fully Understanding Eating and Lifestyle Change (FUEL)

NCT05562427
View directory record Official record
Conditions
Obesity
Interventions
Gold-Standard Online Behavioral Obesity Treatment
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Chromium, Phyllanthus Emblica, and Shilajit on Cardiovascular Health, Fitness, and Weight Loss During Exercise and Diet Programs

NCT06641596
View directory record Official record
Conditions
Overweight, Metabolic Syndrome X
Interventions
Placebo, Cr-400, Cr-800, PE-500, PE-1000
Dietary Supplement
Lead sponsor
Kerry Group P.L.C
Industry
Eligibility
30 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study of Receiving Feedback Messages Based on Self-monitored Dietary Intake

NCT02829632
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Group Sessions, Feedback, Self-monitoring
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 5, 2016 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Supervised and Unsupervised Physical Activity Programs During a Weight Loss Intervention for Adults

NCT02693132
View directory record Official record
Conditions
Obesity
Interventions
Supervised (SUP-PA), Unsupervised (UNSUP-PA), Step-based (STEP)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistance Exercise and Protein During Weight Loss

NCT03600311
View directory record Official record
Conditions
Weight Loss, Starvation
Interventions
Caloric Restriction, Post-Exercise Protein, Energy Balance, Post-Exercise Carbohydrate, Calcium and Vitamin D
Other · Dietary Supplement
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
19 Years to 30 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 12, 2019 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sustainable Culturally Adapted Nutrition (SCAN) Program

NCT07220057
View directory record Official record
Conditions
Diabetes
Interventions
Live instructional video sessions, Links to educational videos, Diabetes Prevention Program (DPP), Produce Delivery
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Oct 14, 2026, 5:14 PM EDT
Not listed Not applicable Interventional

The ReNEW Study: Maestro® New Enrollment Post-Approval Study Protocol

NCT03145636
View directory record Official record
Conditions
Obesity, Morbid
Interventions
vBloc Maestro Rechargeable System, vBloc Achieve Weight Management Program, Control Weight Management (CWM) program
Device · Other
Lead sponsor
ReShape Lifesciences
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
2
States / cities
Scottsdale, Arizona • Mineola, New York
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Not applicable Interventional

Lifestyle, Exercise and Nutrition Study 2 (LEAN 2)

NCT02110641
View directory record Official record
Conditions
Breast Cancer, Weight Loss
Interventions
Weight Loss Counseling
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Oct 14, 2026, 5:14 PM EDT
Not yet recruiting Not applicable Interventional

Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans

NCT07560969
View directory record Official record
Conditions
Diabetes, Physical Activity, Food Security, Nutrition Security
Interventions
Culturally-tailored, enhanced adaption of Diabetes Prevention Program
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Not applicable Interventional

The Effects of a Pre-packaged, Portion Controlled Meal Plan on Type 2 Diabetes and Glycemic Control: A Comparison Study

NCT01260337
View directory record Official record
Conditions
Obesity
Interventions
Portion controlled diet, Diabetes Support and Education
Behavioral · Other
Lead sponsor
Temple University
Other
Eligibility
21 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 1, 2013 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Not applicable Interventional

Enlighten: An Adaptive Technology Weight Loss Intervention

NCT01855932
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Technology Supported
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 24, 2013 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Behavioral Lifestyle Intervention for Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) in Adults

NCT06121999
View directory record Official record
Conditions
Metabolic Associated-dysfunction Steatotic Liver Disease (MASLD), Metabolic Associated-dysfunction Steatohepatitis (MASH)
Interventions
Standard of care acceptance-based behavioral weight loss program, Occupational therapy dietary and lifestyle modifications
Behavioral
Lead sponsor
Grand Valley State University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Wyoming, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of a Personalized vs. Standard Approach to Weight Loss Recommendations

NCT04639076
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Behavioral Weight Loss Program, Personalized Behavioral Weight Loss Program
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
20 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Oct 14, 2026, 5:14 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/Obesity

NCT05912621
View directory record Official record
Conditions
Obesity, Overweight and Obesity, Overweight
Interventions
Tirzepatide
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Considering Patient Diet Preferences to Optimize Weight Loss

NCT01152359
View directory record Official record
Conditions
Obesity
Interventions
Choice, Control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Up to 74 Years
Enrollment
207 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2019 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Phase 1Phase 2 Interventional

Patient-Centered Weight Loss Program for Knee Replacement Patients

NCT02728661
View directory record Official record
Conditions
ARTHROPLASTY, REPLACEMENT
Interventions
PACE, Delayed PACE
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
40 Years to 79 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Weight Loss Intervention for the Reduction of Cancer Risk and Health Disparities in Rural Ohio

NCT05040152
View directory record Official record
Conditions
Obesity-Related Malignant Neoplasm
Interventions
Dietary Counseling and Surveillance, Exercise Intervention, Informational Intervention, Questionnaire Administration, Telephone-Based Intervention
Behavioral · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
20 Years to 64 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 17, 2025 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Get Active and Eat Right: Moms at Work

NCT01668316
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Weight loss
Behavioral
Lead sponsor
University of North Carolina, Greensboro
Other
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated May 3, 2019 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Phase 3 Interventional

Practice-based Trial of Blood Pressure Control in African Americans

NCT01070056
View directory record Official record
Conditions
Hypertension, Physical Activity, Diet, Medication Adherence
Interventions
Therapeutic Lifestyle Changes (MINT-TLC), Usual Care
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
4
States / cities
Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2013 · Synced Oct 14, 2026, 5:14 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Effect of Weight Loss and Exercise on Liver and Muscle Fat in Obese Elderly

NCT00779207
View directory record Official record
Conditions
Obesity
Interventions
weight loss and exercise, weight loss
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 24, 2008 · Synced Oct 14, 2026, 5:14 PM EDT
Recruiting Not applicable Interventional

EMPOWER: Effects of Weight Loss and Exercise Post-stroke

NCT05901675
View directory record Official record
Conditions
Obesity, Stroke
Interventions
Lifestyle Management Program, Post-stroke Optimization of Walking using Explosive Resistance
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
35 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 14, 2026, 5:14 PM EDT
Recruiting Phase 3 Interventional

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

NCT07533175
View directory record Official record
Conditions
Diabetes Mellitus, Overweight, Obesity
Interventions
NNC0487-0111, Placebo (matched to NNC0487-0111)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
630 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
15
States / cities
Birmingham, Alabama • Escondido, California • Lomita, California + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 14, 2026, 5:14 PM EDT