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ClinicalTrials.gov public records Last synced Oct 1, 2026, 10:09 PM EDT

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Showing 25–48 of 543 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Exercise and Dietary Weight Loss Clear all
Completed Phase 3 Interventional

Weight Loss and Exercise in Physically Limited Obese Elderly Subjects

NCT00146133
View directory record Official record
Conditions
Obesity, Frailty, Elderly
Interventions
diet, exercise
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 3, 2006 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Not applicable Interventional

Impact of a POPOP on Preoperative Health, Eligibility, and Clinical & Patient-Reported Outcomes in TJA

NCT04910048
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Avascular Necrosis, Rheumatoid Arthritis
Interventions
POPOP (preoperative patient optimization program), SOC (standard of care)
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 1, 2026, 10:09 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Promotion of Weight Management

NCT04131647
View directory record Official record
Conditions
Overweight
Interventions
Weight Maintenance, Weight Maintenance + Intermittent Fasting
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 75 Years
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Baltimore, Maryland • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Not applicable Interventional

Soy-Based Meal Replacement in Helping Women With Stage I, Stage II, or Stage III Breast Cancer in Complete Remission Lose Weight

NCT00343434
View directory record Official record
Conditions
Breast Cancer, Obesity
Interventions
behavioral dietary intervention, exercise intervention, soy isoflavones, soy protein isolate, counseling intervention, educational intervention, psychosocial assessment and care, quality-of-life assessment
Behavioral · Dietary Supplement · Other + 1 more
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 120 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimal Timing of Exercise Initiation Within a Lifestyle Weight Loss Program

NCT01985568
View directory record Official record
Conditions
Obesity
Interventions
Sequential BT, Standard BT
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 1, 2026, 10:09 PM EDT
Not listed Not applicable Interventional

Roux-en-Y-Gastric Bypass vs. Lifestyle Modification and Medical Therapy in the Treatment of Type 2 Diabetes

NCT01231308
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Roux-en-Y-Gastric Bypass, Intensive lifestyle modification and Optimal medical Therapy
Procedure · Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
21 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 24, 2012 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Not applicable Interventional

Controlled Trial of WLS vs. CLI for Severely Obese Adolescents With NASH

NCT02412540
View directory record Official record
Conditions
Obesity, Nonalcoholic Steatohepatitis, Nonalcoholic Fatty Liver Disease
Interventions
Comprehensive Lifestyle Intervention
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 19 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Phase 1 Interventional

Effect of Liraglutide (Victoza) on Inflammation in Human Adipose Tissue and Blood

NCT02650206
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type II, Diabetes Mellitus, Adult-Onset, Inflammation
Interventions
Victoza (liraglutide) with dietician monitoring, Placebo with dietician monitoring
Drug · Other
Lead sponsor
Stanford University
Other
Eligibility
40 Years to 69 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2020 · Synced Oct 1, 2026, 10:09 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks

NCT05674799
View directory record Official record
Conditions
Overweight or Obesity
Interventions
NDPP-NextGen
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 39 Years · Female only
Enrollment
403 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 1, 2026, 10:09 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Novel Intervention for Weight Loss in Young Adults

NCT06230744
View directory record Official record
Conditions
Weight Loss
Interventions
Lifestyle, Lifestyle II
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 40 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ProduceRx: Improving Weight and Cardiovascular Risk in Adults With Food Insecurity and Obesity

NCT05362747
View directory record Official record
Conditions
Obesity
Interventions
Behavioral weight loss and produce vouchers
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SMART Weight Loss Management

NCT02997943
View directory record Official record
Conditions
Weight Loss
Interventions
Step 1 Treatment: APP, Step 1 Treatment: APP + Coaching, Step 2 Treatment Strategy: Modest Step-up, Step 2 Treatment Strategy: Vigorous Step-up
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 18, 2021 · Synced Oct 1, 2026, 10:09 PM EDT
Active, not recruiting Not applicable Interventional

Group Lifestyle Balance™ for Individuals With Stroke (GLB-CVA)

NCT03873467
View directory record Official record
Conditions
Stroke
Interventions
Group Lifestyle Balance, Usual Care
Behavioral · Other
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 85 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Get Social: Randomized Trial of a Social Network Delivered Lifestyle Intervention

NCT02646618
View directory record Official record
Conditions
Weight Loss
Interventions
Get Social, Traditional, Smartphone
Behavioral · Device
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 65 Years
Enrollment
329 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 24, 2023 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Primary Care Pediatrics Learning Activity and Nutrition With Families

NCT02873715
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Family-based treatment, Usual Care
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
6 Years and older
Enrollment
1,010 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
4
States / cities
St Louis, Missouri • Buffalo, New York • Rochester, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2024 · Synced Oct 1, 2026, 10:09 PM EDT
Terminated Phase 3 Interventional

A 14-Month Study On The Effects Of CP-945,598 For The Prevention Of Weight Regain In Obese Patients

NCT00483171
View directory record Official record
Conditions
Obesity
Interventions
CP-945,598, Non-pharmacological weight loss program (NPP), Low Calorie Diet
Drug · Behavioral
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 70 Years
Enrollment
699 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
9
States / cities
La Jolla, California • Denver, Colorado • Baton Rouge, Louisiana + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2012 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High Physical Activity During a Weight Loss Intervention for Breast Cancer Survivors and High Risk Women

NCT03270111
View directory record Official record
Conditions
Breast Cancer Female
Interventions
Supervised Exercise, Home-based Exercise, Reduced Energy Diet, Group Phone Calls
Behavioral
Lead sponsor
Carol Fabian, MD
Other
Eligibility
50 Years to 70 Years · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Dec 18, 2024 · Synced Oct 1, 2026, 10:09 PM EDT
Not yet recruiting Not applicable Interventional

Optimization of Dietary Adherence in a Mobile Weight Loss Intervention

NCT07582536
View directory record Official record
Conditions
Overweight and/or Obesity
Interventions
Core, Switch to Simplified Diet Monitoring, Goal Autonomy/Planning, Just-in-time (JIT) Messaging, Coach Sessions
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
580 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Combined Effects of Nutritional and Exercise Countermeasures

NCT00447044
View directory record Official record
Conditions
Muscular Atrophy, Muscle Weakness
Interventions
Resistance Exercise, diet orange soda, essential amino acids
Behavioral · Dietary Supplement
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 50 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 19, 2009 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Self-compassion and Nutrition (SCAN) Study

NCT04289636
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Behavioral weight loss program, Self-compassion, Nutrition and cooking education
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Not applicable Interventional Results available

Proof-of-Concept Study of an Integrated Mobile and Social Network Weight Loss Intervention

NCT05295849
View directory record Official record
Conditions
Obesity
Interventions
Building Habits Together Online Weight Loss 6-Week Usability Trial
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Not applicable Interventional Results available

Time Course Adaptations Using Deuterated Creatine (D3Cr) Method

NCT03573583
View directory record Official record
Conditions
Sarcopenia
Interventions
Resistance Training, Successful Aging
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
70 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 1, 2026, 10:09 PM EDT
Recruiting Not applicable Interventional

Trial of Food Is Medicine Approaches for Obesity Treatment in Adults With Food Insecurity

NCT07396805
View directory record Official record
Conditions
Obesity & Overweight
Interventions
BWL, VOUCHER, HOME
Behavioral · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 1, 2026, 10:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Parent Supported Weight Reduction in Down Syndrome

NCT01256112
View directory record Official record
Conditions
Down Syndrome
Interventions
Parent Supported Behavioral Intervention, Nutrition/Activity Education (NAE)
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
13 Years to 26 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Oct 1, 2026, 10:09 PM EDT