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ClinicalTrials.gov public records Last synced Oct 12, 2026, 5:24 PM EDT

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Showing 193–216 of 543 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Exercise and Dietary Weight Loss Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Lifestyle Change Via Tailored mHealth Feedback to Improve Health

NCT03367936
View directory record Official record
Conditions
Overweight and Obesity
Interventions
One-on-one Session, Self-monitoring, Feedback
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
502 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 13, 2025 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Not applicable Interventional

Evaluating the Effect of Diabetes Control Through Intensive Lifestyle Modifications on Diabetic Peripheral Neuropathy

NCT01565317
View directory record Official record
Conditions
Diabetic Polyneuropathy, Weight Loss
Interventions
Weight Achievement and Intensive Treatment (Why WAIT)
Other
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 12, 2026, 5:24 PM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Mechanistic Insights to Weight Loss Maintenance Through SGLT2 Inhibitors

NCT05885074
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Empagliflozin Arm, Control Arm, Exercise capacity VO2 maximum determination, Exercise Challenge
Drug · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Not applicable Interventional

Energy Balance for Prostate Cancer Survivorship

NCT02252484
View directory record Official record
Conditions
Prostate Cancer
Interventions
Weight Loss Program, Standard of Care
Other
Lead sponsor
Jill Hamilton-Reeves, PhD RD LD
Other
Eligibility
50 Years to 72 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 7, 2016 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Not applicable Interventional

Assisted Exercise in Obese Endometrial Cancer Patients

NCT01870947
View directory record Official record
Conditions
Stage I Endometrial Adenocarcinoma, Uterine Cancer, Obesity
Interventions
Exercise on stationary recumbent exercise cycle, Health Education, Questionnaires, Neuroimaging, Genetic and Biomarkers
Behavioral · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Weight Loss Intervention for the Reduction of Cancer Risk and Health Disparities in Rural Ohio

NCT05040152
View directory record Official record
Conditions
Obesity-Related Malignant Neoplasm
Interventions
Dietary Counseling and Surveillance, Exercise Intervention, Informational Intervention, Questionnaire Administration, Telephone-Based Intervention
Behavioral · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
20 Years to 64 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 17, 2025 · Synced Oct 12, 2026, 5:24 PM EDT
Active, not recruiting Not applicable Interventional

The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes

NCT01047735
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
Procedure · Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
25 Years to 55 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Not applicable Interventional Results available

Proof-of-Concept Study of an Integrated Mobile and Social Network Weight Loss Intervention

NCT05295849
View directory record Official record
Conditions
Obesity
Interventions
Building Habits Together Online Weight Loss 6-Week Usability Trial
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Phase 4 Interventional Results available

Intervention to Promote Weight Loss in Latinas At-risk for Diabetes

NCT02088034
View directory record Official record
Conditions
Diabetes
Interventions
Promotora-led Intervention, Metformin Therapy, Usual Care
Behavioral · Drug · Other
Lead sponsor
Temple University
Other
Eligibility
20 Years to 75 Years · Female only
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 22, 2020 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Phase 2 Interventional

Effects of Physical Activity and Dietary Change in Minority Breast Cancer Survivors

NCT00811824
View directory record Official record
Conditions
Breast Cancer
Interventions
Physical activity and dietary change
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
21 Years to 70 Years · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 22, 2013 · Synced Oct 12, 2026, 5:24 PM EDT
Recruiting Phase 3 Interventional

AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

NCT07339423
View directory record Official record
Conditions
Obesity
Interventions
NNC0487-0111, Placebo (matched to NNC0487-0111)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
1,150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
22
States / cities
Miramar, Florida • Orlando, Florida • Conyers, Georgia + 19 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Not applicable Interventional

Impact of GBS on CVD in Type 2 Diabetes Mellitus

NCT00787670
View directory record Official record
Conditions
Obesity, Type 2 Diabetes Mellitus
Interventions
Diabetes Support and Education, gastric bypass surgery, Tissue Control Group
Other · Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years to 60 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2013 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diet, Exercise, Metabolism, and Obesity in Older Women

NCT00664729
View directory record Official record
Conditions
Abdominal Obesity, Metabolic Syndrome
Interventions
Caloric Restriction, Caloric Restriction + Low-Intensity aerobic exercise, Caloric Restriction plus High-intensity aerobic exercise
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
50 Years to 70 Years · Female only
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2008
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Not applicable Interventional

Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors

NCT06171945
View directory record Official record
Conditions
Cancer, Physical Activity, Cancer Survivorship, Mental Health, Obesity
Interventions
AYA Connect intervention, Positive Psychology (PP) intervention, Positive Psychology Plus (PP+) intervention
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 39 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Loss Intervention in Long-Haul Truck Drivers: A Pilot Study

NCT02348983
View directory record Official record
Conditions
Obesity
Interventions
Health Coaching via Telephone
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
21 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 30, 2015 · Synced Oct 12, 2026, 5:24 PM EDT
Not yet recruiting Not applicable Interventional

Simplifying Diet Tracking in a Digital Weight Loss Intervention

NCT07601061
View directory record Official record
Conditions
Overweight, Obesity, Weight Loss, Health Behavior, Lifestyle Intervention
Interventions
Simplified Dietary Self-Monitoring, Detailed Dietary Self-Monitoring, Core Behavioral Weight Loss Intervention
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
328 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Not applicable Interventional

Solutions for Hunger And Regulating Eating

NCT05004883
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Regulation of Cues Enhanced, Behavioral Weight Loss, Nutrition Education, Stress Management and Social Support
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
293 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 12, 2026, 5:24 PM EDT
Not listed Not applicable Interventional

Online Obesity Treatment in Primary Care (Rhode Island, USA)

NCT03488212
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Training to Identify Eligible Patients and Direct them to Online Obesity Treatment Program, Training to Motivate and Support Patients' Weight Loss, Online Behavioral Weight Loss Intervention, Control Intervention for Weight Loss Maintenance and Weight Gain Prevention, Monthly Lessons and Feedback Intervention for Weight Loss Maintenance and Weight Gain Prevention, Refresher Courses for Weight Loss Maintenance and Weight Gain Prevention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 20, 2020 · Synced Oct 12, 2026, 5:24 PM EDT
Terminated Not applicable Interventional Results available

Safety and Effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS)-Assisted Weight Loss

NCT03299881
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Transcutaneous Nerve Stimulator (TENS), Diet & Exercise
Device · Behavioral
Lead sponsor
Elira Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 10, 2021 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Not applicable Interventional

Improving Autonomic Function and Balance in Diabetic Neuropathy

NCT01864460
View directory record Official record
Conditions
Diabetes, Neuropathy, Impaired Glucose Tolerance
Interventions
lifestyle modification
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
30 Years to 80 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 12, 2026, 5:24 PM EDT
Not listed Not applicable Interventional

Creating an Optimized Technology-Based Weight Loss Program for Cardiac Rehabilitation Patients

NCT03845283
View directory record Official record
Conditions
Cardiovascular Diseases, Obesity
Interventions
Online Behavioral Weight Loss Program, Physical Activity Intervention, Bite Counter, Virtual Reality, Virtual Meetings
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
21 Years to 75 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Phase 2Phase 3 Interventional

Improving Diabetes Through Lifestyle and Surgery

NCT01667783
View directory record Official record
Conditions
Obesity, Type 2 Diabetes
Interventions
Gastric Banding, Medical Weight Loss, Gastric Bypass
Procedure · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 64 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 12, 2024 · Synced Oct 12, 2026, 5:24 PM EDT
Recruiting Not applicable Interventional

Cultural Modification of an Evidence Based Healthy Lifestyle Intervention for People Post Stroke Who Identify as Hispanic/Latino

NCT06517459
View directory record Official record
Conditions
Stroke
Interventions
Group Lifestyle Balance
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 12, 2026, 5:24 PM EDT
Completed Not applicable Interventional

Lifestyle Intervention for Treatment of Diabetes

NCT01806727
View directory record Official record
Conditions
Type 2 Diabetes, Overweight, Obesity
Interventions
Community Lifestyle Weight Loss (LWL), Diabetes Self Management (DSM)
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
21 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 12, 2026, 5:24 PM EDT