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ClinicalTrials.gov public records Last synced Sep 9, 2026, 2:41 AM EDT

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Showing 1–24 of 59 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Exhaled Nitric Oxide Clear all
Terminated No phase listed Observational

Evaluation of FeNO During and Following Acute COPD Exacerbation

NCT01761006
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
NIOX MINO®
Device
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Sep 9, 2026, 2:41 AM EDT
Completed Phase 2 Interventional Results available

Study to Evaluate the Efficacy and Safety of MEDI-563 in Adults With Uncontrolled Asthma

NCT01238861
View directory record Official record
Conditions
Asthma
Interventions
Benralizumab 2 mg, Benralizumab 20 mg, Benralizumab 100 mg, Placebo
Biological · Other
Lead sponsor
MedImmune LLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
964 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
27
States / cities
Birmingham, Alabama • Los Angeles, California • Orange, California + 24 more
Source: ClinicalTrials.gov public record
Updated Nov 16, 2016 · Synced Sep 9, 2026, 2:41 AM EDT
Completed Phase 2 Interventional

24hr Effects of Tiotropium Bromide in Tetraplegia

NCT02586649
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Tiotropium Bromide, Placebo
Drug
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 15, 2020 · Synced Sep 9, 2026, 2:41 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Exhaled Nitric Oxide Levels in Infants and Young Children Infected With RSV or Other Viral Infections

NCT01098227
View directory record Official record
Conditions
Bronchiolitis, Infection, Nitric Oxide
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
Up to 4 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Mar 15, 2020 · Synced Sep 9, 2026, 2:41 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Exhaled Levels of Nitric Oxide

NCT00753948
View directory record Official record
Conditions
Tetraplegia, Asthma
Interventions
N-Nitro L-arginine-methylester (L-NAME)
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 27, 2020 · Synced Sep 9, 2026, 2:41 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Measurement of FeNO in Young Children With the NIOX VERO

NCT02661984
View directory record Official record
Conditions
Asthma
Interventions
Not listed
Lead sponsor
Aerocrine AB
Industry
Eligibility
4 Years to 6 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
3
States / cities
Gilbert, Arizona • Blue Bell, Pennsylvania • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Sep 9, 2026, 2:41 AM EDT
Active, not recruiting Phase 4 Interventional

Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting Beta-agonist (ICS/LABA) in Comparison to ICS Dose Escalation to High Dose ICS/LABA in Adolescent and Adult Patients With Uncontrolled Asthma

NCT06572228
View directory record Official record
Conditions
Asthma
Interventions
dupilumab, Matching Placebo, ICS/LABA
Drug
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
12 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
51
States / cities
Bakersfield, California • La Jolla, California • Lancaster, California + 47 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 9, 2026, 2:41 AM EDT
Completed Phase 2 Interventional Results available

L-arginine in Severe Asthma Patients Grouped by Exhaled Nitric Oxide Levels

NCT01841281
View directory record Official record
Conditions
Asthma, Inflammation
Interventions
L-Arginine, Placebo
Drug
Lead sponsor
Nicholas Kenyon
Other
Eligibility
19 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2020 · Synced Sep 9, 2026, 2:41 AM EDT
Not listed Phase 4 Interventional

Coreg CR, Blood Vessel Stiffness and Blood Vessel Function

NCT00732511
View directory record Official record
Conditions
Endothelial Function, Diabetes Mellitus, Hypertension
Interventions
carvedilol, metoprolol extended release
Drug
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Feb 9, 2011 · Synced Sep 9, 2026, 2:41 AM EDT
Completed No phase listed Observational

Exhaled NO as a Biomarker of Gestational OSA and Persistence Postpartum

NCT02100943
View directory record Official record
Conditions
Pregnancy, OSA
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 19, 2017 · Synced Sep 9, 2026, 2:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nitrate Supplementation During Final Examination Stress

NCT03159273
View directory record Official record
Conditions
Airway Disease
Interventions
Beetroot Juice Group
Dietary Supplement
Lead sponsor
Southern Methodist University
Other
Eligibility
18 Years to 50 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2018 · Synced Sep 9, 2026, 2:41 AM EDT
Recruiting No phase listed Observational

Use of fenoTRACK Device for Monitoring Changes of Fractional Exhaled Nitric Oxide (FeNO) in Uncontrolled Asthma Subjects and Controlled Asthma Subjects

NCT07228026
View directory record Official record
Conditions
Asthma
Interventions
fenoTRACK Device
Device
Lead sponsor
Biometry Inc
Industry
Eligibility
5 Years to 100 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
13
States / cities
Stockton, California • Panama City, Florida • Columbus, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 9, 2026, 2:41 AM EDT
Not yet recruiting Not applicable Interventional

Inhaled Nitric Oxide in Severe Obesity

NCT06675435
View directory record Official record
Conditions
Obesity, Respiratory Insufficiency, Hypoxemic Respiratory Failure, Nitric Oxide
Interventions
Nitric oxide
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 9, 2026, 2:41 AM EDT
Completed No phase listed Observational

Measuring Exhaled Nitric Oxide (eNO) Using the Apieron INSIGHT System and the Aerocrine NIOX System

NCT00739531
View directory record Official record
Conditions
Asthma
Interventions
Exhaled nitric oxide (eNO)
Device
Lead sponsor
Apieron
Industry
Eligibility
5 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
2
States / cities
Shreveport, Louisiana • Lake Oswego, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 20, 2008 · Synced Sep 9, 2026, 2:41 AM EDT
Completed No phase listed Observational

The Use of Fractionated Exhaled Nitric Oxide in the Diagnosis and Assessment of Disease Activity of Eosinophilic Esophagitis (Pilot)

NCT03812575
View directory record Official record
Conditions
Eosinophilic Esophagitis
Interventions
Not listed
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
5 Years to 18 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 9, 2024 · Synced Sep 9, 2026, 2:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Exhaled Nitric Oxide in Respiratory Syncytial Virus (RSV) Bronchiolitis: a Pilot Study

NCT01090557
View directory record Official record
Conditions
RSV Infection, Bronchiolitis
Interventions
Collection of exhaled breath
Other
Lead sponsor
Winthrop University Hospital
Other
Eligibility
1 Day to 4 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Mar 21, 2010 · Synced Sep 9, 2026, 2:41 AM EDT
Terminated No phase listed Observational

The Use of Exhaled Nitric Oxide in Conjunction With the Asthma Control Test to Determine Asthma Control in Pediatric Patients

NCT00575445
View directory record Official record
Conditions
Asthma
Interventions
Not listed
Lead sponsor
Akron Children's Hospital
Other
Eligibility
6 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 24, 2015 · Synced Sep 9, 2026, 2:41 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude

NCT07216755
View directory record Official record
Conditions
Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training, Exercise Intolerance, Dietary Supplement, Nitrate Supplementation, Inspiratory Muscle Training
Interventions
Respiratory Muscle Training (RMT), Sham Respiratory Muscle Training, Dietary Supplement: Beetroot Juice Concentrate, placebo beverage
Device · Dietary Supplement
Lead sponsor
Embry-Riddle Aeronautical University
Other
Eligibility
18 Years to 40 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Daytona Beach, Florida
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 9, 2026, 2:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Utilizing Exhaled Breathe Condensate Collection to Study Ion Regulation in Cystic Fibrosis

NCT01880723
View directory record Official record
Conditions
Cystic Fibrosis, Healthy
Interventions
Albuterol, Placebo saline
Drug
Lead sponsor
University of Arizona
Other
Eligibility
15 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Sep 9, 2026, 2:41 AM EDT
Completed Not applicable Interventional Results available

Vivatmo Pro™ for Fractional Exhaled Nitric Oxide (FeNO) Monitoring in U.S. Asthmatic Patients

NCT04450108
View directory record Official record
Conditions
Asthma, Asthma in Children
Interventions
Vivatmo pro FeNO Test
Diagnostic Test
Lead sponsor
Bosch Healthcare Solutions GmbH
Industry
Eligibility
7 Years to 80 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
6
States / cities
Birmingham, Alabama • Bakersfield, California • White Marsh, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2022 · Synced Sep 9, 2026, 2:41 AM EDT
Enrolling by invitation Phase 2 Interventional Accepts healthy volunteers

Determining Airway pH by Compartmental Exhaled Nitric Oxide Levels During Alkaline Buffer Challenge

NCT04738422
View directory record Official record
Conditions
Airway Disease
Interventions
Alkaline glycine
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 60 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 9, 2026, 2:41 AM EDT
Completed No phase listed Observational

Observational Study of Obstructive Lung Disease (NOVELTY)

NCT02760329
View directory record Official record
Conditions
Asthma, COPD, Chronic Obstructive Pulmonary Disease
Interventions
Blood draw, Urine, Lung function measurements, Fractional Exhaled Nitric Oxide (FENO)
Procedure
Lead sponsor
AstraZeneca
Industry
Eligibility
12 Years to 130 Years
Enrollment
12,255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
40
States / cities
Loma Linda, California • Long Beach, California • Roseville, California + 33 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Sep 9, 2026, 2:41 AM EDT
Completed Not applicable Interventional Results available

Dietary Supplementation With Soy Isoflavones in Asthma

NCT00277446
View directory record Official record
Conditions
Asthma
Interventions
Soy isoflavones
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 50 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 24, 2011 · Synced Sep 9, 2026, 2:41 AM EDT
Not listed Phase 1 Interventional

Effects of Anticholinergic or Long-Acting Beta 2 Agonist on FeNO and Pulmonary Function in SCI

NCT01355991
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Tiotropium, Salmeterol
Drug
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
West Orange, New Jersey • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 22, 2015 · Synced Sep 9, 2026, 2:41 AM EDT