Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 10, 2026, 4:57 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Aging Well
Interventions
Acute bout of Continuous Moderate Intensity Exercise, Acute bout of High Intensity Interval Training, Control
Other
Lead sponsor
University of Virginia
Other
Eligibility
65 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Charlottesville, Virginia
Not yet recruiting Not applicable Interventional

Cognitive Training for Functioning in PTSD

NCT07693686
Conditions
Posttraumatic Stress Disorder
Interventions
COGENT (Cognitive ENhancement Training), ST (Sham Training)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
San Diego, California
Conditions
Memory Deficit
Interventions
Memory Drilling, Compensatory Strategies, Cognitive Processing Therapy
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Spinal Cord Injury, Blood Pressure, Cerebral Blood Flow, Cognitive Function
Interventions
SPT, SPT Control, mSMT, mSMT Control
Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
West Orange, New Jersey
Completed Not applicable Interventional Results available

Cognitive Rehabilitation in Schizophrenia

NCT00248794
Conditions
Cognitive Impairment, Schizophrenia
Interventions
Cognitive Rehabilitation Therapy (CRT) + Skill Training (SDG), Individual Computer Based Cognitive Rehabilitation (ICBCR) and Skills Training (SDG), Skills Group (SDG)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
West Haven, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

Brain Enhancement Training Towards Elders Resilience to Aging

NCT03197454
Conditions
Age-related Cognitive Decline
Interventions
Computerized Plasticity-Based Adaptive Cognitive Training, Commercially available computerized training
Other
Lead sponsor
Posit Science Corporation
Industry
Eligibility
65 Years and older
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Iowa City, Iowa • Dallas, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dietary Ketosis: Fatty Acids Activate AMPK Energy Circuits Modulating Global Methylation

NCT03319173
Conditions
Mild Cognitive Impairment, Metabolic Syndrome
Interventions
Dietary intervention
Behavioral
Lead sponsor
Bristlecone Health, Inc.
Industry
Eligibility
35 Years to 80 Years
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Maple Grove, Minnesota
Conditions
Traumatic Brain Injury
Interventions
memory retraining exercises, placebo control memory exercises
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 59 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
West Orange, New Jersey
Conditions
Multiple Sclerosis
Interventions
Strategy-Based Training to Enhance Memory (STEM), Placebo control exercises
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 59 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
East Hanover, New Jersey • Marlton, New Jersey
Completed Not applicable Interventional Accepts healthy volunteers

Obesity Treatment Enhanced With Working Memory Training

NCT02529397
Conditions
ADHD, Weight Loss
Interventions
Adaptive Working Memory Training, Non-adaptive cognitive training
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Burlington, Vermont
Conditions
Healthy Adolescents
Interventions
Adaptive Attention Training, Active Control, Low-dose Adaptive Attention Training
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
12 Years to 16 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
San Francisco, California
Conditions
Primary Progressive Aphasia, Semantic Dementia, Semantic Memory Disorder, Logopenic Progressive Aphasia, Nonfluent Aphasia, Progressive, Aphasia, Aphasia, Progressive
Interventions
Multicomponent Lexical Retrieval Training (Multi-LRT), Multicomponent Video Implemented Script Training in Aphasia (Multi-VISTA), Multicomponent Communication Partner Training (Multi-CPT)
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Austin, Texas
Conditions
Mild Cognitive Impairment (MCI), Early Stages of Cognitive Decline, Alzheimer's Disease Dementia, Alzheimer's Disease Diagnosis, Alzheimer's Disease and Related Dementias, Parkinson's Disease, Parkinson's Disease (PD), Parkinson's Disease With Wearing-off Motor Fluctuations, Dementia (Diagnosis), Dementia MCI (Mild Cognitive Impairment)
Interventions
Structured wellness care, Wearable brain-computer interface devices, Stem Cell Therapy - Experimental, Control - Placebo Comparator
Behavioral · Device · Biological + 1 more
Lead sponsor
Noah Tech, Corp.
Industry
Eligibility
55 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Palisades Park, New Jersey
Conditions
Multiple Sclerosis, Progressive, Cognition - Other, Memory Impairment
Interventions
Memory retraining exercises, Placebo control memory exercises
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
30 Years to 59 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
West Orange, New Jersey
Completed Not applicable Interventional Accepts healthy volunteers

Brain Enhancement Training Towards Elders Resilience to Aging, Phase IIB

NCT05599490
Conditions
Age-related Cognitive Decline
Interventions
Computerized Plasticity-Based Adaptive Cognitive Training
Other
Lead sponsor
Posit Science Corporation
Industry
Eligibility
70 Years and older
Enrollment
135 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Iowa City, Iowa • Dallas, Texas
Conditions
Aging
Interventions
STEM
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
60 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
East Hanover, New Jersey
Conditions
Motivation, Memory, Self-regulation
Interventions
Ventral tegmental area of dopaminergic midbrain (VTA) fMRI neurofeedback
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 45 Years
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
HIV
Interventions
PATH For Triples, Treatment as Usual
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Recruiting Not applicable Interventional

Virtual Reality Attention Management

NCT03221244
Conditions
ADHD
Interventions
VR Treatment, VR Active Control
Device
Lead sponsor
University of California, Davis
Other
Eligibility
8 Years to 12 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Sacramento, California
Conditions
Dementia
Interventions
QEEG-based Neurofeedback Training
Behavioral
Lead sponsor
Quietmind Foundation
Other
Eligibility
45 Years to 85 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Lafayette Hill, Pennsylvania
Conditions
Falls (Accidents) in Old Age
Interventions
FallsTalk-C, FallsTalk
Behavioral
Lead sponsor
Brookside Research & Development Company
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Freeland, Washington
Conditions
Schizophrenia
Interventions
Brain Fitness Program (BFP), Cognitive Package (Cogpack), Commercial Computer Games (Sporcle)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
25 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Los Angeles, California • West Los Angeles, California
Not yet recruiting Not applicable Interventional

Exercise With and Without Cognitive Training

NCT07447115
Conditions
Multiple Sclerosis
Interventions
Effect of Exercise with and Without Cognitive Training on Gait
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Decatur, Georgia
Not listed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Exercise in College Students With ADHD

NCT03666416
Conditions
Attention Deficit Hyperactivity Disorder, Effects of; Exertion, Working Memory, Change in Sustained Attention
Interventions
Sprint Interval Training
Behavioral
Lead sponsor
University of Wyoming
Other
Eligibility
18 Years to 29 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Laramie, Wyoming