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ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:05 AM EDT

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Showing 1–24 of 24 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: FENO Clear all
Completed No phase listed Observational Accepts healthy volunteers

Real World and Genomic Data Based Asthma Insight Through Network Analysis

NCT06623435
View directory record Official record
Conditions
Asthma
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
1,075 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
5
States / cities
Denver, Colorado • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 29, 2026, 4:05 AM EDT
Not yet recruiting No phase listed Observational

Quantifying the Burden of Type 2 (T2) Inflammation in Asthma

NCT07675044
View directory record Official record
Conditions
Asthma, Type 2 Asthma
Interventions
FeNO Breath Test
Diagnostic Test
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 29, 2026, 4:05 AM EDT
Active, not recruiting Phase 4 Interventional

Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting Beta-agonist (ICS/LABA) in Comparison to ICS Dose Escalation to High Dose ICS/LABA in Adolescent and Adult Patients With Uncontrolled Asthma

NCT06572228
View directory record Official record
Conditions
Asthma
Interventions
dupilumab, Matching Placebo, ICS/LABA
Drug
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
12 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
51
States / cities
Bakersfield, California • La Jolla, California • Lancaster, California + 47 more
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Not applicable Interventional Results available

Vivatmo Pro™ for Fractional Exhaled Nitric Oxide (FeNO) Monitoring in U.S. Asthmatic Patients

NCT04450108
View directory record Official record
Conditions
Asthma, Asthma in Children
Interventions
Vivatmo pro FeNO Test
Diagnostic Test
Lead sponsor
Bosch Healthcare Solutions GmbH
Industry
Eligibility
7 Years to 80 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
6
States / cities
Birmingham, Alabama • Bakersfield, California • White Marsh, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Oct 29, 2026, 4:05 AM EDT
Not yet recruiting Not applicable Interventional

Inhaled Nitric Oxide in Severe Obesity

NCT06675435
View directory record Official record
Conditions
Obesity, Respiratory Insufficiency, Hypoxemic Respiratory Failure, Nitric Oxide
Interventions
Nitric oxide
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Phase 1Phase 2 Interventional

Vitamin D Deficiency and Replacement on Pulmonary and Endocrine Function in SCI

NCT02099955
View directory record Official record
Conditions
Spinal Cord Injury, Vitamin D Deficiency
Interventions
Vitamin D3
Drug
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2017 · Synced Oct 29, 2026, 4:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Impact of FeNO Measured With the NIOX MINO® Device in Identifying Asthma Among Patients With Prolonged Respiratory Symptoms

NCT01518322
View directory record Official record
Conditions
Asthma
Interventions
NIOX MINO®
Device
Lead sponsor
Aerocrine AB
Industry
Eligibility
7 Years to 65 Years
Enrollment
235 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
13
States / cities
Byron, Minnesota • Chatfield, Minnesota • Pine Island, Minnesota + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 30, 2013 · Synced Oct 29, 2026, 4:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Exhaled Nitric Oxide in Respiratory Syncytial Virus (RSV) Bronchiolitis: a Pilot Study

NCT01090557
View directory record Official record
Conditions
RSV Infection, Bronchiolitis
Interventions
Collection of exhaled breath
Other
Lead sponsor
Winthrop University Hospital
Other
Eligibility
1 Day to 4 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Mar 22, 2010 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Phase 4 Interventional

FeNO as a Marker of Allergic Reactions to OFC and Response of OMA Treatment in Multiple FA

NCT06437171
View directory record Official record
Conditions
Food Allergy
Interventions
Omalizumab
Biological
Lead sponsor
AAADRS Clinical Research Center
Other
Eligibility
6 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Oct 28, 2026 · Synced Oct 29, 2026, 4:05 AM EDT
Completed No phase listed Observational Results available

A Study to Explore the Utility of Fractional Exhaled Nitric Oxide (FeNO) Compared With Methacholine Challenge (MCC) Testing in the Assessment of Patients With Suspected But Undiagnosed Asthma

NCT01648920
View directory record Official record
Conditions
Asthma
Interventions
NIOX MINO® Instrument (09-1100)
Device
Lead sponsor
Aerocrine AB
Industry
Eligibility
7 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
8
States / cities
Blue Bell, Pennsylvania • Collegeville, Pennsylvania • Doylestown, Pennsylvania + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2014 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Phase 2 Interventional Results available

Study to Evaluate the Efficacy and Safety of MEDI-563 in Adults With Uncontrolled Asthma

NCT01238861
View directory record Official record
Conditions
Asthma
Interventions
Benralizumab 2 mg, Benralizumab 20 mg, Benralizumab 100 mg, Placebo
Biological · Other
Lead sponsor
MedImmune LLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
964 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
27
States / cities
Birmingham, Alabama • Los Angeles, California • Orange, California + 24 more
Source: ClinicalTrials.gov public record
Updated Nov 17, 2016 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Phase 4 Interventional

Study to Investigate Changes in Airway Inflammation, Symptoms, and Rescue Therapy Utilization With AIRSUPRA Compared to Albuterol as Needed in Adults With Mild Asthma

NCT06563102
View directory record Official record
Conditions
Mild Asthma
Interventions
Albuterol/Budesonide, Albuterol
Combination Product
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 120 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
16
States / cities
Phoenix, Arizona • Tucson, Arizona • Lancaster, California + 13 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 29, 2026, 4:05 AM EDT
Not listed Phase 1 Interventional

Effects of Anticholinergic or Long-Acting Beta 2 Agonist on FeNO and Pulmonary Function in SCI

NCT01355991
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Tiotropium, Salmeterol
Drug
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
West Orange, New Jersey • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 23, 2015 · Synced Oct 29, 2026, 4:05 AM EDT
Terminated Phase 4 Interventional

Management of Asthma Patients Guided by Exhaled Nitric Oxide (eNO)

NCT00739219
View directory record Official record
Conditions
Asthma
Interventions
Apieron Insight eNO monitor
Device
Lead sponsor
Apieron
Industry
Eligibility
12 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
12
States / cities
Mission Viejo, California • San Jose, California • Glastonbury, Connecticut + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 29, 2026, 4:05 AM EDT
Recruiting Not applicable Interventional

Vascular ARDS Recruitment After Inhaled Nitric Oxide

NCT05801224
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome, Ventilation Perfusion Mismatch
Interventions
Nitric Oxide
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 29, 2026, 4:05 AM EDT
Completed No phase listed Observational Results available

Use of FeNO to Identify Eosinophilic Inflammation in Patients Age 40 Years and Above With Chronic Obstructive Airways Disease

NCT01634620
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
NIOX MINO® Instrument (09-1100)
Device
Lead sponsor
Aerocrine AB
Industry
Eligibility
40 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Sanford, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 12, 2014 · Synced Oct 29, 2026, 4:05 AM EDT
Completed No phase listed Observational

Measuring Exhaled Nitric Oxide (eNO) Using the Apieron INSIGHT System and the Aerocrine NIOX System

NCT00739531
View directory record Official record
Conditions
Asthma
Interventions
Exhaled nitric oxide (eNO)
Device
Lead sponsor
Apieron
Industry
Eligibility
5 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
2
States / cities
Shreveport, Louisiana • Lake Oswego, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 21, 2008 · Synced Oct 29, 2026, 4:05 AM EDT
Completed No phase listed Observational

Observational Study of Obstructive Lung Disease (NOVELTY)

NCT02760329
View directory record Official record
Conditions
Asthma, COPD, Chronic Obstructive Pulmonary Disease
Interventions
Blood draw, Urine, Lung function measurements, Fractional Exhaled Nitric Oxide (FENO)
Procedure
Lead sponsor
AstraZeneca
Industry
Eligibility
12 Years to 130 Years
Enrollment
12,255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
40
States / cities
Loma Linda, California • Long Beach, California • Roseville, California + 33 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 29, 2026, 4:05 AM EDT
Completed No phase listed Observational Results available

Study to Evaluate the Impact of FeNO Assessments on Asthma Management Decisions in Subject 7 to 60 Years of Age

NCT01729247
View directory record Official record
Conditions
Asthma
Interventions
NIOX MINO® Instrument (09-1100)
Device
Lead sponsor
Aerocrine AB
Industry
Eligibility
7 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 3, 2014 · Synced Oct 29, 2026, 4:05 AM EDT
Terminated No phase listed Observational

Evaluation of FeNO During and Following Acute COPD Exacerbation

NCT01761006
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
NIOX MINO®
Device
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 7, 2017 · Synced Oct 29, 2026, 4:05 AM EDT
Recruiting No phase listed Observational

Use of fenoTRACK Device for Monitoring Changes of Fractional Exhaled Nitric Oxide (FeNO) in Uncontrolled Asthma Subjects and Controlled Asthma Subjects

NCT07228026
View directory record Official record
Conditions
Asthma
Interventions
fenoTRACK Device
Device
Lead sponsor
Biometry Inc
Industry
Eligibility
5 Years to 100 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
13
States / cities
Stockton, California • Panama City, Florida • Columbus, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 29, 2026, 4:05 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Measurement of FeNO in Young Children With the NIOX VERO

NCT02661984
View directory record Official record
Conditions
Asthma
Interventions
Not listed
Lead sponsor
Aerocrine AB
Industry
Eligibility
4 Years to 6 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
3
States / cities
Gilbert, Arizona • Blue Bell, Pennsylvania • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 15, 2017 · Synced Oct 29, 2026, 4:05 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Savannah Environmental Nutrition Study (SENS): Nutrition Intervention to Reduce Air Pollution-Related Airway Inflammation and Oxidative Stress

NCT07797413
View directory record Official record
Conditions
Air Pollution Exposure, Oxidative Stress, Airway Inflammation
Interventions
Antioxidant- and Nutrient-Rich Food-Based Nutrition Intervention
Other
Lead sponsor
Georgia Southern University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Savannah, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 29, 2026, 4:05 AM EDT
Completed Phase 2 Interventional Results available

Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH)

NCT02781584
View directory record Official record
Conditions
Nonalcoholic Steatohepatitis (NASH), Nonalcoholic Fatty Liver Disease (NAFLD)
Interventions
SEL, FIR, CILO, FENO, VAS
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
12
States / cities
Chandler, Arizona • La Jolla, California • Los Angeles, California + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2022 · Synced Oct 29, 2026, 4:05 AM EDT