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ClinicalTrials.gov public records Last synced Oct 18, 2026, 2:55 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 66 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: FFR Clear all
Completed No phase listed Observational

Fast Assessment of STenosis Severity- FASTII Study

NCT03791320
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Vessel Fractional Flow Reserve
Diagnostic Test
Lead sponsor
Erasmus Medical Center
Other
Eligibility
18 Years and older
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 24, 2020 · Synced Oct 18, 2026, 2:55 PM EDT
Completed Not applicable Interventional

Validation of Stenosis Assessment by Coronary Artery Computed Tomography Against Invasive Measurements of Fractional Flow Reserve in Patients With Significant Coronary Artery Stenoses

NCT00817102
View directory record Official record
Conditions
Coronary Artery Stenosis
Interventions
FFR, IVUS, VH, or combination of the three
Procedure
Lead sponsor
Piedmont Healthcare
Other
Eligibility
21 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 15, 2014 · Synced Oct 18, 2026, 2:55 PM EDT
Terminated No phase listed Observational

The Evaluation of the Roles of New Cardiac Imaging in Patients With Chest Pain

NCT03800862
View directory record Official record
Conditions
Cardiology, Radiology, Stenoses
Interventions
CT-FFR and CTP
Device
Lead sponsor
Lancaster General Hospital
Other
Eligibility
45 Years to 85 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 27, 2022 · Synced Oct 18, 2026, 2:55 PM EDT
Terminated No phase listed Observational

Measurements to Assess Severity of Epicardial Stenoses

NCT00760630
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
FFR/CFR and IVUS
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 18, 2026, 2:55 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Neural Indices of Intervention Outcomes in Children With Speech Sound Disorders

NCT03623100
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Speech Production Treatment., Speech Production + Speech Perception Treatment.
Behavioral
Lead sponsor
Idaho State University
Other
Eligibility
4 Years to 6 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2026
U.S. locations
1
States / cities
Meridian, Idaho
Source: ClinicalTrials.gov public record
Updated May 9, 2025 · Synced Oct 18, 2026, 2:55 PM EDT
Recruiting No phase listed Observational

The NAVIGATE-PCI Registry: A New Approach to VIew CT-derived Guidance Ahead of Stenting To Plan Efficient PCI

NCT07479433
View directory record Official record
Conditions
Coronary Artery Disease (CAD)
Interventions
Heartflow PCI Navigator
Diagnostic Test
Lead sponsor
HeartFlow, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Oct 18, 2026, 2:55 PM EDT
Recruiting Not applicable Interventional

Adjustment Disorders in the US Military: Disease Trajectories and ADNM-20-Mil Validation

NCT06885554
View directory record Official record
Conditions
Adjustment Disorders
Interventions
SANA
Device
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
San Diego, California • Wright-Patterson Air Force Base, Ohio • Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 18, 2026, 2:55 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

FFRangio Accuracy vs. Standard FFR

NCT03226262
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
FFRangio
Device
Lead sponsor
CathWorks Ltd.
Industry
Eligibility
18 Years and older
Enrollment
382 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
4
States / cities
Stanford, California • New York, New York • Roslyn, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2018 · Synced Oct 18, 2026, 2:55 PM EDT
Completed No phase listed Observational

Radiographic Imaging Validation and EvALuation for Angio iFR (ReVEAL iFR)

NCT03857503
View directory record Official record
Conditions
Cardiac Ischemia, Coronary Artery Disease, Coronary Stenosis
Interventions
iFR
Diagnostic Test
Lead sponsor
Volcano Corporation
Industry
Eligibility
18 Years and older
Enrollment
441 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
19
States / cities
Long Beach, California • Lakewood, Colorado • New Haven, Connecticut + 15 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2021 · Synced Oct 18, 2026, 2:55 PM EDT
Completed No phase listed Observational Results available

The PLATFORM Study: Prospective LongitudinAl Trial of FFRct: Outcome and Resource IMpacts)

NCT01943903
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
HeartFlow, Inc.
Industry
Eligibility
18 Years and older
Enrollment
584 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
3
States / cities
Redwood City, California • Stanford, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 5, 2025 · Synced Oct 18, 2026, 2:55 PM EDT
Recruiting Not applicable Interventional

Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease

NCT05701358
View directory record Official record
Conditions
Acute Myocardial Infarction, Coronary Artery Disease
Interventions
Physiology-guided NCL PCI, Angiography-guided NCL PCI
Procedure
Lead sponsor
Population Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
5,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
13
States / cities
Los Angeles, California • San Francisco, California • Wichita, Kansas + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2025 · Synced Oct 18, 2026, 2:55 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Breathing-Maneuver-Induced Myocardial Oxygenation Reserve Validated by FFR (B-MORE)

NCT04126148
View directory record Official record
Conditions
Coronary Artery Stenosis
Interventions
Not listed
Lead sponsor
Matthias Friedrich
Other
Eligibility
18 Years and older
Enrollment
236 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 18, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

PrEssure wiRe Compared to Microcatheter-based Sensing Technology For the Evaluation of FFR Measurements

NCT02648230
View directory record Official record
Conditions
Ischemia, Angina
Interventions
St. Jude Medical Pressure Wire, ACIST Navvus Microcatheter
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 14, 2019 · Synced Oct 18, 2026, 2:55 PM EDT
Terminated No phase listed Observational

Use of Magnetocardiography in Evaluation of Patients Going for Cardiac Catheterization

NCT04044391
View directory record Official record
Conditions
Acute Coronary Syndrome, Coronary Artery Stenosis, Myocardial Ischemia
Interventions
CardioFlux Magnetocardiograph
Diagnostic Test
Lead sponsor
Genetesis Inc.
Industry
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Detroit, Michigan • Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated May 26, 2020 · Synced Oct 18, 2026, 2:55 PM EDT
Enrolling by invitation Not applicable Interventional

Cortical Contributions to FFR: Post-Op Outcomes

NCT05214092
View directory record Official record
Conditions
Language
Interventions
Speech sound stimulation
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years to 25 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 18, 2026, 2:55 PM EDT
Completed No phase listed Observational Results available

Observational Study of OCT in a Patients Undergoing FFR

NCT01663896
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
OCT stent guidance
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
418 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
15
States / cities
Birmingham, Alabama • La Jolla, California • Orlando, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2020 · Synced Oct 18, 2026, 2:55 PM EDT
Not listed No phase listed Observational

FFR vs. icECG in Coronary Bifurcations

NCT01724957
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Intracoronary ECG
Procedure
Lead sponsor
University National Heart Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Oct 18, 2026, 2:55 PM EDT
Completed Not applicable Interventional

Trial to Compare FFR Measurement With a Non-Side-Hole Guide Catheter Vs. a Side-Hole Guide Catheter

NCT02480569
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
FFR Measurement
Other
Lead sponsor
North Texas Veterans Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2016 · Synced Oct 18, 2026, 2:55 PM EDT
Active, not recruiting No phase listed Observational

Fractional Flow Reserve and Instantaneous Free-wave Ratio Revascularization Strategies in Women

NCT04599192
View directory record Official record
Conditions
Coronary Disease, Percutaneous Coronary Intervention, Exercise Test, Myocardial Perfusion Imaging, Cardiac Catheterization
Interventions
No study intervention
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 18, 2026, 2:55 PM EDT
Completed No phase listed Observational

Fractional Flow Reserve (FFR) Versus Instant Wave-Free Ratio (iFR)

NCT01559493
View directory record Official record
Conditions
Coronary Artery Disease, Plaque, Atherosclerotic
Interventions
Not listed
Lead sponsor
NHS National Waiting Times Centre Board
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 21, 2012 · Synced Oct 18, 2026, 2:55 PM EDT
Terminated No phase listed Observational

Diagnostic Performance of Coronary CT Angiography With CT FFR in Kidney Transplantation Candidates

NCT03248674
View directory record Official record
Conditions
Coronary Artery Disease, Computed Tomography
Interventions
CT FFR
Diagnostic Test
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 6, 2022 · Synced Oct 18, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease

NCT02100722
View directory record Official record
Conditions
Coronary Disease, Coronary Stenosis
Interventions
FFR guided PCI, CABG, Resolute Integrity Stent, Resolute Onyx Stent
Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
13
States / cities
Palo Alto, California • Stanford, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 18, 2026, 2:55 PM EDT
Not listed No phase listed Observational

The Value of CT-FFR Compared to CCTA or CCTA and Stress MPI in Low to Intermediate Risk ED Patients With Toshiba CT-FFR

NCT03329469
View directory record Official record
Conditions
Coronary Artery Disease, Chest Pain, Acute Coronary Syndrome, Acute Myocardial Infarction
Interventions
Toshiba CT-FFR
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
1,142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Oct 18, 2026, 2:55 PM EDT
Not yet recruiting No phase listed Observational

Simultaneous Measurement of EpicArdial and Microvascular ResisTance Via Angiographic FLOW Study

NCT07676097
View directory record Official record
Conditions
Non-obstructive Coronary Disease, Acute or Chronic Coronary Artery Disease
Interventions
Patients with intermediate coronary artery stenosis with clinically indicated FFR assessment., Microvascular assessment
Procedure
Lead sponsor
AngioInsight
Industry
Eligibility
18 Years and older
Enrollment
620 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
9
States / cities
Palo Alto, California • Washington D.C., District of Columbia • Minneapolis, Minnesota + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 18, 2026, 2:55 PM EDT