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Showing 409–432 of 560 matching trials from the live ClinicalTrials.gov search.
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Vascular Impairment in Type II Diabetes Mellitus With Co-morbid Obstructive Sleep Apnea

NCT01629862
Conditions
Sleep Apnea, Obstructive, Diabetes Mellitus
Interventions
Continuous positive airway pressure, Sham continuous positive airway pressure
Device
Lead sponsor
Sanjay R Patel
Other
Eligibility
18 Years to 70 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
2
States / cities
Boston, Massachusetts
Conditions
Intracuff Pressure
Interventions
Ambu LMA, Gastro LMA
Device
Lead sponsor
Jason Bryant
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Full Face Snorkel Masks (FFSMs)

NCT04783688
Conditions
Snorkeling, Face Mask Squeeze, Underwater Physiology, Swimming Physiology
Interventions
Full Face Snorkel Mask (FFSM)
Other
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Results available

Aerosolization During Upper Endoscopy

NCT06006078
Conditions
Infectious, Gastro-Intestinal Disorder, Safety Issues
Interventions
Endoscopic Patient Facemask
Device
Lead sponsor
Anthony Lembo
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Colonoscopy, Oxygenation, Ventilation
Interventions
Oxygen via nasal cannula, Oxygen via SuperNO2VA nasal mask
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Nashville, Tennessee
Terminated Not applicable Interventional

NIV for COPD: Hospital to Home

NCT04413643
Conditions
Pulmonary Disease, Chronic Obstructive, Noninvasive Ventilation
Interventions
Noninvasive Ventilation
Device
Lead sponsor
San Francisco Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
San Francisco, California
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Arformoterol tartrate inhalation solution, Tiotropium
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
55 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
28
States / cities
Birmingham, Alabama • Flagstaff, Arizona • Waterbury, Connecticut + 24 more
Conditions
Post Surgical Respiratory Failure, Respiratory Complication, Opioid Induced Respiratory Depression, Respiratory Arrest
Interventions
Linshom Continuous Predictive Respiratory Monitoring
Device
Lead sponsor
Linshom Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
394 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Baltimore, Maryland • Columbus, Ohio
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Neuroimaging During Pure Oxygen Breathing

NCT03268590
Conditions
Hyperoxia, Hypoxia, Brain, Neurobehavioral Manifestations
Interventions
Oxygen
Drug
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 60 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Focus is on Healthy Subjects
Interventions
Reusable, Transparent, and Reconfigurable N95-Equivalent Respirator Masks: Design, Fabrication, and Clinical Trials for Enhanced Adoption
Device
Lead sponsor
SEEUS95 Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Early Phase 1 Interventional Accepts healthy volunteers

Nitrous Oxide Neuroimaging

NCT06702631
Conditions
Anesthesia, Pain, Amnesia
Interventions
Nitrous oxide, Peripheral Nerve Stimulation
Drug · Device
Lead sponsor
Keith M Vogt
Other
Eligibility
18 Years to 59 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Terminated Not applicable Interventional Results available

Pediatric Helmet CPAP Pilot Study

NCT04764929
Conditions
Bronchiolitis, Viral, Pneumonia, Viral, Pneumonia, Bacterial
Interventions
Helmet CPAP
Device
Lead sponsor
Columbia University
Other
Eligibility
1 Month to 5 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Conditions
Obstructive Sleep Apnea
Interventions
Oxygen Therapy, Questionnaire Administration, Optiflow THRIVE
Procedure · Other · Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Houston, Texas
Conditions
Eating Disorders
Interventions
Family-Based Therapy ("Maudsley Method"), Individual Supportive Psychotherapy
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
10 Years to 17 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional

Saline Hypertonic in Preschoolers

NCT02378467
Conditions
Cystic Fibrosis
Interventions
7% Hypertonic Saline (HS), 0.9% Isotonic Saline (IS)
Drug
Lead sponsor
University of Washington, the Collaborative Health Studies Coordinating Center
Other
Eligibility
3 Years to 5 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
23
States / cities
Birmingham, Alabama • Palo Alto, California • Aurora, Colorado + 20 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Doctors for Coronavirus Prevention Project Thanksgiving / Christmas Messaging Campaign

NCT04644328
Conditions
Covid19
Interventions
Facebook Ads on the importance of staying safe during the Thanksgiving / Christmas holiday
Behavioral
Lead sponsor
National Bureau of Economic Research, Inc.
Other
Eligibility
18 Years and older
Enrollment
820 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cambridge, Massachusetts
Conditions
Continuous Positive Airway Pressure, High Altitude Pulmonary Edema
Interventions
CPAP mask system, Nifedipine 30 MG, CPAP mask system without PEEP
Device · Drug
Lead sponsor
CommonSpirit Health
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Breckenridge, Colorado
Completed Not applicable Interventional Accepts healthy volunteers

A Comparison of the Ambu AuraGain Versus LMA Supreme in Children

NCT02380768
Conditions
Supraglottic Airway
Interventions
Ambu AuraGain (size 1.5 or size 2.0), LMA Supreme (size 1.5 or size 2.0)
Device
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
3 Months to 6 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Chicago, Illinois
Terminated Not applicable Interventional Accepts healthy volunteers

Effectiveness of Chest Compressions Under Mild Hypoxia

NCT04072484
Conditions
Cardiac Arrest, Hypoxia
Interventions
Mild hypoxia
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 70 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Cognition
Interventions
Hyperbaric oxygen therapy
Procedure
Lead sponsor
Pediatric Partners of Ponte Vedra
Other
Eligibility
6 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Ponte Vedra Beach, Florida
Completed Not applicable Interventional Results available

Nitrous Oxide Induction Induces Amnesia in Pediatric Patients

NCT02050152
Conditions
Amnesia
Interventions
Nitrous Oxide 0%, Nitrous oxide 33%, Nitrous oxide 66%
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
6 Years to 12 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Critical Illness, Hypoxia, Respiratory Failure
Interventions
End-tidal oxygen monitor
Device
Lead sponsor
Sydney Local Health District
Government
Eligibility
18 Years and older
Enrollment
1,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Minneapolis, Minnesota • Albuquerque, New Mexico • The Bronx, New York
Conditions
Perinatal Death, Respiratory Distress Syndrome, Newborn, Hypoxic-Ischemic Encephalopathy, Neonatal Seizure, Meconium Aspiration Syndrome, Intracranial Hemorrhages, Neonatal Hypotension
Interventions
Room air
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 55 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Loma Linda, California
Conditions
Ankylosing Spondylitis
Interventions
Bimekizumab, Certolizumab pegol, Placebo
Drug · Other
Lead sponsor
UCB Biopharma SRL
Industry
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
4
States / cities
Ormond Beach, Florida • Lincoln, Nebraska • Oklahoma City, Oklahoma + 1 more