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ClinicalTrials.gov public records Last synced Nov 1, 2026, 12:59 AM EDT

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Showing 193–216 of 560 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Face Mask Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Noninvasive Ventilation Masks Carbon Dioxide Clearance in Normal Volunteers

NCT03882723
View directory record Official record
Conditions
CO2 Clearance, Mask Comfort, Rebreathing Exhaled Gas
Interventions
Evaluated 4 masks used for NIV with mechanical ventilators
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Nov 1, 2026, 12:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nitrous Oxide Versus Intravenous Sedation for Anesthesia

NCT02755090
View directory record Official record
Conditions
Pregnancy Termination in Second Trimester
Interventions
Nitrous Oxide, IV Saline
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Denver, Colorado • Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 15, 2017 · Synced Nov 1, 2026, 12:59 AM EDT
Completed Not applicable Interventional Results available

Strategy to Avoid Excessive Oxygen Using an Autonomous Oxygen Titration Intervention

NCT06374225
View directory record Official record
Conditions
Critical Illness, Wounds and Injury, Disease Attributes, Pathologic Processes
Interventions
Automated Titration (O2matic)
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Aurora, Colorado • Winston-Salem, North Carolina • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Nov 1, 2026, 12:59 AM EDT
Not yet recruiting Phase 4 Interventional

A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections

NCT07387315
View directory record Official record
Conditions
Overactive Bladder, Neurogenic Bladder, Urge Incontinence, Pain, Urinary Incontinence, Urinary Bladder, Overactive, Urinary Bladder, Neurogenic, Urinary Bladder Neurogenesis, Urinary Incontinence, Urge, Pelvic Floor Disorders
Interventions
Pro-Nox Nitrous Oxide/Oxygen Delivery System, Standard Care for Bladder Botox Injection, Sham Mask
Drug · Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Nov 1, 2026, 12:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reaching for Equity in Sleep Apnea Treatment (REST) Study

NCT04209985
View directory record Official record
Conditions
Sleep Apnea
Interventions
Health coaching
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Nov 1, 2026, 12:59 AM EDT
Terminated Phase 2 Interventional Results available

Sleep Apnea Treatment After Stroke (SATS)

NCT00282815
View directory record Official record
Conditions
Obstructive Sleep Apnea, Stroke
Interventions
continuous positive airway pressure or CPAP, sham CPAP
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 11, 2013 · Synced Nov 1, 2026, 12:59 AM EDT
Completed Not applicable Interventional

Oran Park Mask External Clinical Study (3) Marketing Claims Study

NCT06079866
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Mask A (Oran Park Mask) then Mask B (Evora Mask), Mask B (Evora Mask) then Mask A (Oran Park Mask)
Device
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
2
States / cities
San Diego, California • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Nov 1, 2026, 12:59 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

VentFirst: A Multicenter RCT of Assisted Ventilation During Delayed Cord Clamping for Extremely Preterm Infants

NCT02742454
View directory record Official record
Conditions
Intraventricular Hemorrhage
Interventions
Standard 30-60 Seconds Cord Clamping, VentFirst 120 Seconds Cord Clamping
Procedure
Lead sponsor
University of Virginia
Other
Eligibility
Not listed
Enrollment
570 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
10
States / cities
Birmingham, Alabama • Sacramento, California • Denver, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Nov 1, 2026, 12:59 AM EDT
Recruiting Not applicable Interventional

Evaluation of the F&P Mask, US, 2026

NCT07826429
View directory record Official record
Conditions
Chronic Respiratory Conditions, Obstructive Sleep Apnea (OSA)
Interventions
F&P Licorice Mask
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Nov 1, 2026, 12:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a N95 Respirator vs Cloth Mask on Exercise Capacity During Treadmill Exercise.

NCT04415879
View directory record Official record
Conditions
COVID-19
Interventions
N-95 Respirator, Cloth Face Mask
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Nov 1, 2026, 12:59 AM EDT
Completed Not applicable Interventional

Sleep Enhancing Tools: Pilot Study

NCT02068703
View directory record Official record
Conditions
Sleep, Pain
Interventions
Sleep Education Presentation, Sleep Tool Demonstration
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 28, 2016 · Synced Nov 1, 2026, 12:59 AM EDT
Completed Not applicable Interventional Results available

Effect of Clear Masks on Patient Satisfaction With Communication

NCT05088603
View directory record Official record
Conditions
Communication, Patient Satisfaction
Interventions
Clear Mask
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
19 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Nov 1, 2026, 12:59 AM EDT
Recruiting Phase 2 Interventional

Study to Evaluate the Safety, Pharmacology and Efficacy of WIN378 in Adults With Moderate or Severe Asthma

NCT07120503
View directory record Official record
Conditions
Asthma
Interventions
WIN378, Placebo
Drug
Lead sponsor
Windward Bio
Industry
Eligibility
18 Years to 75 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
21
States / cities
Los Angeles, California • San Jose, California • Melbourne, Florida + 18 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Nov 1, 2026, 12:59 AM EDT
Completed Phase 4 Interventional Results available

Budesonide Inhalation Suspension for Acute Asthma in Children

NCT00393367
View directory record Official record
Conditions
Asthma, Acute Asthma, Reactive Airway Exacerbation
Interventions
Budesonide inhalation suspension (0.5 mg/2mL) 2mg, albuterol (5mg/mL) 7.5 or 10mg, Prednisolone, prednisone, or methylprednisolone, Albuterol, ipratropium bromide, Ipratropium bromide
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Years to 18 Years
Enrollment
179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 10, 2012 · Synced Nov 1, 2026, 12:59 AM EDT
Not listed Not applicable Interventional

Carbon Monoxide Monitoring and Emergency Treatment

NCT00841165
View directory record Official record
Conditions
Carbon Monoxide Poisoning
Interventions
Continuous Positive Airway Pressure, Non-rebreather oxygen mask
Device
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Apr 2, 2010 · Synced Nov 1, 2026, 12:59 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Comparing Desflurane to Sevoflurane for the Effect on Recovery Time in Patients Undergoing Urological Cystoscope Surgery

NCT01219881
View directory record Official record
Conditions
Cystoscopes, Baxter Anaesthesia Brand of Desflurane, Sevoflurane
Interventions
Desflurane, Sevoflurane
Drug
Lead sponsor
Ohio State University
Other
Eligibility
50 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 16, 2021 · Synced Nov 1, 2026, 12:59 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Real-time Assessment of Frameless Intrafraction Motion

NCT01202539
View directory record Official record
Conditions
Brain Tumor
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 3, 2019 · Synced Nov 1, 2026, 12:59 AM EDT
Recruiting Not applicable Interventional

Hypoxia Pathways for Early Recovery After Spinal Cord Injury

NCT07002437
View directory record Official record
Conditions
Spinal Cord Injuries (SCI)
Interventions
Augmented Acute Intermittent Hypoxia (aAIH), Acute Intermittent Hypercapnic-Hypoxia (AIHH), Sham AIH
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Nov 1, 2026, 12:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Pilot Study of CPAP Adherence Promotion by Peer Buddies With Sleep Apnea

NCT01164683
View directory record Official record
Conditions
Sleep Apnea
Interventions
Peer-driven intervention, Usual Care
Behavioral · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Nov 1, 2026, 12:59 AM EDT
Completed Not applicable Interventional

Aromatherapy Effect on Anxiety Prior to Ultrasound Guided Musculoskeletal Procedures

NCT05660486
View directory record Official record
Conditions
Anxiety State
Interventions
Aromatherapy, Placebo
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Nov 1, 2026, 12:59 AM EDT
Completed Early Phase 1 Interventional

Effect of a Novel Intervention Using Daily Intermittent Hypoxia and High Intensity Training on Upper Limb Function in Individuals With Spinal Cord Injury

NCT03643770
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Upper extremity training/Armeo Spring
Combination Product
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 75 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Nov 1, 2026, 12:59 AM EDT
Completed Not applicable Interventional

High Flow Nasal Cannula With Noninvasive Ventilation

NCT04507425
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Standard of Care - Nasal Cannula, High-flow nasal cannula, HFNC plus non-invasive ventilation
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 100 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Nov 1, 2026, 12:59 AM EDT
Completed Not applicable Interventional

Comparison of Two-hand Mask Ventilation Technique: Standard V-E Versus Reversal V-E Technique

NCT03170037
View directory record Official record
Conditions
Intubation
Interventions
Standard V-E ventilation technique, Reversal V-E ventilation technique
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 17, 2017 · Synced Nov 1, 2026, 12:59 AM EDT
Completed No phase listed Interventional Results available

The Evaluation of a Full Face Mask Seal for the Treatment of Obstructive Sleep Apnea

NCT03230877
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Toffee full face mask with 'Improved Seal', Toffee full face mask with 'Normal Seal'
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 8, 2022 · Synced Nov 1, 2026, 12:59 AM EDT