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Conditions: Clonal Hematopoiesis
Interventions: high-fiber plant-based meals, fermented foods, supplements, surveys; Other · Dietary Supplement
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 7
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Weight, Body
Interventions: Time restircted eating, Time restricted eating + prebiotic; Behavioral
Lead sponsor: University of Illinois at Chicago; Other
Eligibility: 18 Years to 39 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Diverticulitis
Interventions: High-dose prebiotic, Low-dose prebiotic, Placebo; Dietary Supplement
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Microbial Colonization
Interventions: Prebiotics, Placebos; Dietary Supplement
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: 2 Years to 18 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Physiological Stress
Interventions: mental stress task; Other
Lead sponsor: Texas State University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 109 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: San Marcos, Texas

Conditions: Age-Related Macular Degeneration
Interventions: Goji berry, Fiber; Dietary Supplement
Lead sponsor: University of California, Davis; Other
Eligibility: 65 Years to 95 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Healthy, Impaired Glucose Tolerance
Interventions: Dietary supplement regimen, Dietary supplement and intermittent fasting regimen; Dietary Supplement · Other
Lead sponsor: Unicity International, Inc.; Industry
Eligibility: 30 Years to 69 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Addison, Illinois

Conditions: Cirrhosis
Interventions: BCAA Supplement, Physical Activity; Dietary Supplement · Other
Lead sponsor: Loyola University; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Libido, Intimacy, Gastrointestinal Issues
Interventions: Reset, Stay Ready Fiber, Libido, Testosterone supplement; Dietary Supplement
Lead sponsor: 906 CMVI Holdings; Industry
Eligibility: 18 Years to 44 Years · Male only
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Solid Tumor
Interventions: Potato starch; Drug
Lead sponsor: University of Michigan Rogel Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Prediabetes
Interventions: Inulin, Placebo; Dietary Supplement
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 40 Years to 70 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Blacksburg, Virginia

Conditions: Sleep Deprivation, Circadian Dysregulation, Stress
Interventions: Insufficient Sleep, Prebiotic, Placebo; Behavioral · Dietary Supplement
Lead sponsor: University of Colorado, Boulder; Other
Eligibility: 18 Years to 45 Years
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Boulder, Colorado

Conditions: Overweight (BMI > 25), Obese, Otherwise Healthy Volunteers
Interventions: Placebo, Probiotic; Dietary Supplement
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years to 60 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Storrs, Connecticut

Conditions: Crohn Disease, Ulcerative Colitis
Interventions: Prebiotic; Dietary Supplement
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 85 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Behavioral Measures of Tolerance
Interventions: Previously marketed cow's mlik-based infant formula, Marketed cow's milk-based infant formula with prebiotics; Other
Lead sponsor: Mead Johnson Nutrition; Industry
Eligibility: 14 Days to 35 Days
Enrollment: 161 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 7
States / cities: Fayetteville, Arkansas • Norwich, Connecticut • Evansville, Indiana + 4 more

Conditions: Healthy Participants
Interventions: LOAM, Inulin, Cellulose Placebo; Dietary Supplement
Lead sponsor: Ventoscity LLC; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Term Infants
Interventions: Marketed infant formula with DHA and ARA, Milk-based infant formula with DHA and ARA, Milk-based formula with DHA, ARA, prebiotics; Other
Lead sponsor: Mead Johnson Nutrition; Industry
Eligibility: 10 Days to 18 Days
Enrollment: 136 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 9
States / cities: Birmingham, Alabama • Little Rock, Arkansas • Tamarac, Florida + 5 more

Conditions: Kidney Stones, Nephrolithiasis
Interventions: Empiric Therapy: Diet, Empiric Therapy: Drug, Selective Therapy: Diet, Selective Therapy: Drug; Behavioral · Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Intestinal Graft Versus Host Disease
Interventions: Colonoscopy, Fecal Microbiota Transplantation, Nutritional Supplementation, Survey Administration, Biospecimen Collection; Procedure · Biological · Dietary Supplement + 1 more
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Chronic Obstructive Pulmonary Disease, Aging
Interventions: Fiber Inulin, Placebo Maltodextrin; Dietary Supplement
Lead sponsor: Texas A&M University; Other
Eligibility: 18 Years and older
Enrollment: 87 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: College Station, Texas

Conditions: Obesity
Interventions: LIK066, Carbohydrate 50%, Carbohydrate 25%, Carbohydrate 8%, Carbohydrate 0%, Psyllium, Calcium carbonate; Drug · Dietary Supplement
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Body Weight Changes
Interventions: Meal replacement shake, Multivitamin and mineral capsules, Fish oil with sesame lignans and olive extract softgel, Prebiotic Chewable tablet, Clove Extract and Maqui Berry extract capsule, .Whole Food Blend capsule, Turmeric extract capsule, European White Kidney Bean capsule, Saffron extract capsule, Ubiquinol with Fulvic acid complex softgel, Calcium with Hesperidin and gynostemma extract tablet, Multivitamin and mineral supplement; Dietary Supplement
Lead sponsor: Supplement Formulators, Inc.; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Fort Lauderdale, Florida

Conditions: Prebiotics
Interventions: Fiber cycles ARM 1, Fiber cycles ARM 2, Fiber cycles ARM 3, Fiber cycles ARM 4, Fiber cycles ARM 5, Fiber cycles ARM 6, Fiber cycles ARM 7, Fiber cycles ARM 8, Fiber cycles ARM 9, Fiber cycles ARM 10, Fiber cycles ARM 11, Fiber cycles ARM 12, Fiber cycles ARM 13, Fiber cycles ARM 14, Fiber cycles ARM 15, Fiber cycles ARM 16, Fiber cycles ARM 17, Fiber cycles ARM 18, Fiber cycles ARM 19, Fiber cycles ARM 20, Fiber cycles ARM 21, Fiber cycles ARM 22, Fiber cycles ARM 23, Fiber cycles ARM 24; Dietary Supplement
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Stanford, California

Conditions: Fecal Incontinence
Interventions: Psyllium, Gum Arabic, carboxymethylcellulose, Placebo; Dietary Supplement
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 206 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 1
States / cities: Minneapolis, Minnesota

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A Dietary Study for People With Clonal Hematopoiesis

Time Restricted Eating With or Without a Fiber Supplement for Weight Management in Pediatric Cancer Survivors

Effect of Gum Arabic on Gastrointestinal Transit and Permeability

The Use of A Prebiotic to Promote a Healthy Gut Microbiome in Pediatric Stem Cell Transplant Recipients

Impact of Supplements on Stress Markers

Effects of Goji vs. Fiber on Macular Degeneration

Effects of an Intermittent Fasting and Dietary Supplement Regimen on Glycemic Variability

BCAA Supplemental Study

A Clinical Study to Evaluate the Efficacy of Four Supplements on Improving Readiness for Intimacy

Intestinal Microbiome Modification With Resistant Starch in Patients Treated With Dual Immune Checkpoint Inhibitors

Prebiotics, Gut Microbiota, and Cardiometabolic Health

The Microbiome and Resilience to Sleep and Circadian Disruption

L. Acidophilus (Strain TW01) on Gut Health, Body Composition, and Inflammation

Impact of Prebiotics in Ulcerative Colitis

Nutritive Effects of Prebiotics on Early Postnatal Behavioral Measures of Tolerance

Comparing Prebiotic Fiber Supplements for Gut Health and Digestive Comfort

The Evaluation of Cow Milk-Based Formulas

Empiric Versus Selective Prevention Strategies for Kidney Stone Disease

Fecal Microbiota Transplant and Dietary Fiber Supplementation for the Treatment of Gut Graft Versus Host Disease

Fiber Metabolism in Chronic Obstructive Pulmonary Disease

Effects of Carbohydrate in Diet and Supplements on the Gastrointestinal Tolerability of LIK066

Evaluate the Effects of Repeated Periods of Modified Fasting to Support Healthy Natural Weight Management and Prevention of Weight Gain

Multiomic Signatures of Microbial Metabolites Following Prebiotic Fiber Supplementation

Dietary Fiber for Fecal Incontinence