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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed No phase listed Observational Accepts healthy volunteers

Effects of Sevoflurane and Propofol on Light Flash Evoked Pupillometry

NCT00695890
Conditions
Measurement of Pupil Diameter
Interventions
Not listed
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Newark, New Jersey
Conditions
Mild Cognitive Impairment
Interventions
Circadian-Effective Light, Rhythmic Light, Placebo Light, Placebo Rhythmic Light
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
55 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Menands, New York • New York, New York
Conditions
Primary Progressive Aphasia
Interventions
tACS or multisensory stimulation
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
45 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2035
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Terminated Early Phase 1 Interventional Accepts healthy volunteers

Evaluation of an Eye Tracking Sensor to Detect Cannabis Impairment

NCT03994926
Conditions
Cannabis Intoxication
Interventions
Virtual Reality Eye Tracking after smoking Cannabis - HTC Vive Pro-Eye, Cannabis cigarette - 4.0% THC
Device · Drug
Lead sponsor
Battelle Memorial Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

Rhythmic Light Therapy for Alzheimer's Disease Patients

NCT05015478
Conditions
Mild Cognitive Impairment
Interventions
Tailored Rhythmic Lighting Intervention, Placebo Rhythmic Lighting Intervention
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
55 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Menands, New York • New York, New York
Conditions
Depression, MDD, Major Depressive Disorder, Major Depressive Episode
Interventions
60Hz Intermittent Light Therapy, Sham Light Therapy
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
24 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Delayed Sleep Phase Disorder
Interventions
Flashes
Device
Lead sponsor
Stanford University
Other
Eligibility
15 Years to 19 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Conditions
ADHD
Interventions
Flashed Light Therapy, Videoconference-delivered Cognitive Behavioral Therapy
Device · Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
14 Years to 17 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Not listed Not applicable Interventional Accepts healthy volunteers

Bright Light as a Countermeasure for Circadian Desynchrony

NCT01119365
Conditions
Healthy
Interventions
Bright light
Other
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years to 35 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Completed Not applicable Interventional Results available

Effects of Sensory Flicker and Electrical Flicker Stimulation

NCT04188834
Conditions
Brain Diseases
Interventions
Customized version of DAVID device, Blackrock CereStim
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Dry Eye Disease
Interventions
Intense pulsed light with C.STIM device
Device
Lead sponsor
Quantel Medical
Industry
Eligibility
22 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
4
States / cities
Lexington, Kentucky • Raleigh, North Carolina • Nashville, Tennessee + 1 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Shifting Sleep Timing in Teens

NCT05808179
Conditions
Sleep Insufficiency, Sleep, Adolescent Behavior
Interventions
Light, CBT, Sham Light
Device · Behavioral
Lead sponsor
Stanford University
Other
Eligibility
14 Years to 18 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Stanford, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural Mechanisms of Light Driven Analgesia

NCT07245303
Conditions
Musculoskeletal Pain, Fibromyalgia, Healthy Controls Group - Age and Sex-matched
Interventions
S-cone modulating visual stimulus, Equal Energy White Visual Stimulus, Green light visual stimulus (S-OFF), Evoked Pressure Pain Stimulus
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Corticobasal Syndrome, Upper Extremity Dysfunction
Interventions
Patterned Sensory Enhancement (PSE), Transcranial Direct Current Stimulation (tDCS)
Behavioral · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 89 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

Healthy Little Eyes

NCT05971446
Conditions
Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy, Encephalopathy
Interventions
Visual Evoked Potential (VEP), Electroretinogram (ERG)
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Up to 36 Months
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2029
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Cortical Blindness
Interventions
Multisensory Rehabilitation
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Vocal Cord Atrophy
Interventions
Cone Beam Computed Tomography, Acoustic/Auerodynamic testing, Laryngovideostroboscopy
Other · Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
65 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Study of Stimulus Parameters in Flicker Electroretinogram (ERG)

NCT02466607
Conditions
Retinopathy
Interventions
RETeval color flicker ERG, RETeval dilated versus un-dilated flicker ERG, pupil dilation
Device · Other
Lead sponsor
LKC Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Menopause Hot Flashes
Interventions
Placebo, Fezolinetant
Drug
Lead sponsor
Rebecca Thurston
Other
Eligibility
40 Years to 65 Years · Female only
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Chicago, Illinois • Pittsburgh, Pennsylvania
Recruiting Not applicable Interventional Accepts healthy volunteers

Multimodal Musical Stimulation for Healthy Neurocognitive Aging

NCT06229093
Conditions
Aging
Interventions
Gamma, Synchrony
Device
Lead sponsor
Northeastern University
Other
Eligibility
18 Years to 95 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Diabetic Retinal Disease
Interventions
Visual Acuity, Reading Speed, Visual Field testing, Contrast sensitivity, Electroretinography (ERG) and pupillography in light- and dark-adapted states, Ultrawide field-color photograph, Ultrawide field-Fluorescein angiogram, Optical coherence tomography, Optical coherence tomography- Angiography
Diagnostic Test · Other
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
4
States / cities
Augusta, Georgia • Boston, Massachusetts • Detroit, Michigan + 1 more
Conditions
Parkinson's Disease, Tourette's Syndrome, Tic Disorders, Dystonia, Movement Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Eye-tracking Device, Pulsed vibrator, Gait Trainer Treadmill (GTT), Standard psychiatric scales SCID-I, YBOCS and SCI-OBS-lifetime and cognitive scales MMSE and MOCA, iMobility, QMAT, Treadmill Test, Arm Intellistretch Device, Transcranial Sonography (TCS), Behavioral tasks, TMS single/paired pulse, MEG, EEG, MRI techniques, Peripheral Nerve Stimulation, EMG, Trancutaneous spinal direct current stimulation (tsDCS)
Procedure · Device · Other + 1 more
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
1,273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting Not applicable Interventional Accepts healthy volunteers

Adaptive Optics Retinal Imaging

NCT05370287
Conditions
Glaucoma, Primary Open Angle
Interventions
oxygen inhalation, Adaptive optics imaging
Other · Device
Lead sponsor
Food and Drug Administration (FDA)
Federal
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
1
States / cities
Silver Spring, Maryland
Conditions
Failed or Difficult Intubation
Interventions
3D Laser Scanning of the Head, Measurements and Digital Photo's of the head, neck and Mouth, Ultrasound Exam of the Tongue
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Rochester, New York