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ClinicalTrials.gov public records Last synced Oct 28, 2026, 9:08 PM EDT

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Showing 817–840 of 918 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Fracture Clear all
Completed Phase 4 Interventional Results available

Acute Application of Antibiotic Powder in Open Fracture Wounds

NCT04872400
View directory record Official record
Conditions
Fractures, Open, Wounds and Injuries--Infections, Anti-Bacterial Agents, Fractures, Bone, Extremity Fracture Lower, Extremity Fractures Upper
Interventions
Vancomycin, Tobramycin
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does Early Elbow Motion Improve Patient Outcomes After Surgically Treated Elbow Fractures?

NCT05980312
View directory record Official record
Conditions
Elbow Fracture, Range of Motion, Immobilization
Interventions
Splint Immobilization, Early Motion
Other
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Oct 28, 2026, 9:08 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

A Prospective, Single Center, Observational Study to Assess the Rapid Recovery After Cardiac Surgery Using SternaLock XP

NCT05578651
View directory record Official record
Conditions
Rigid Plate Fixation, Median Sternotomy
Interventions
SternaLock XP
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Manchester, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jan 16, 2025 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Not applicable Interventional

Functional Outcomes After Radial Head Fractures Treated Non-operatively

NCT03170128
View directory record Official record
Conditions
Radial Head Fracture
Interventions
Outpatient physical therapy in addition to standard follow-up visits, Home exercises in addition to standard follow-up visits
Procedure · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 99 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2017 · Synced Oct 28, 2026, 9:08 PM EDT
Not listed Not applicable Interventional

Quantification of Debris Captured Using TCEP During VIV TAVR With BVF

NCT05093764
View directory record Official record
Conditions
Aortic Valve Disease
Interventions
VIV TAVR with BVF using TCEP
Device
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 14, 2024 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Postoperative Aspirin and Ankle Fracture Healing

NCT03765619
View directory record Official record
Conditions
Ankle Fractures
Interventions
Aspirin
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 110 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Oct 28, 2026, 9:08 PM EDT
Terminated Phase 1 Interventional

The Evaluation of Postoperative Antibiotics in Non-Infected Mandible Fractures

NCT04198129
View directory record Official record
Conditions
Jaw Fractures, Infection
Interventions
Antibiotic treatment (Unasyn or Cleocin), Antibiotic treatment (Augmentin or Cleocin), Control Group
Drug · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Phase 3 Interventional Results available

Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma

NCT01345019
View directory record Official record
Conditions
Cancer, Hematologic Malignancies, Multiple Myeloma, Oncology, Bone Metastases, Multiple Myeloma Bone Lesions
Interventions
Denosumab, Zoledronic acid, Placebo to Denosumab, Placebo to zoledronic acid, Denosumab (for the open-label treatment phase)
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years and older
Enrollment
1,718 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
79
States / cities
Tucson, Arizona • Fayetteville, Arkansas • Anaheim, California + 67 more
Source: ClinicalTrials.gov public record
Updated Nov 8, 2022 · Synced Oct 28, 2026, 9:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Bone and Vascular Health in Postmenopausal Women With Type 1 Diabetes

NCT02693964
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Bone density and carotid ultrasound
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
45 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Oct 28, 2026, 9:08 PM EDT
Completed No phase listed Observational Results available

Patient Factors Associated With Fragmentation of Copper Intrauterine Device (IUD) Requiring Hysteroscopic Removal

NCT07351084
View directory record Official record
Conditions
Intrauterine Device Complications, Contraceptive Device Failure, IUD Fragmentation, Retained Intrauterine Device, Female Contraception, Women's Health, Reproductive Health
Interventions
Not listed
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
44 participants
Timeline
2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Phase 3 Interventional

Evaluation of AVE5026 as Compared to Placebo for the Extended Prophylaxis of Venous Thromboembolism in Patients Having Undergone Hip Fracture Surgery

NCT00709904
View directory record Official record
Conditions
Venous Thromboembolism
Interventions
Open-label Semuloparin sodium, Placebo (for Semuloparin sodium), Semuloparin sodium
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
469 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 14, 2013 · Synced Oct 28, 2026, 9:08 PM EDT
Terminated Phase 2Phase 3 Interventional

A Phase 2/3 Multicenter, Controlled Trial Of rhBMP-2/CPM In Tibial Fractures

NCT00387686
View directory record Official record
Conditions
Fractures
Interventions
rhBMP-2/CPM
Drug
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
18 Years and older
Enrollment
367 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
17
States / cities
Birmingham, Alabama • Aurora, Colorado • Denver, Colorado + 13 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2013 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Not applicable Interventional Results available

Waterproof Casting for Pediatric Distal Radius Fractures

NCT02095106
View directory record Official record
Conditions
Pediatric Distal Radius Fractures
Interventions
Waterproof Cast, Traditional cast
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
4 Years to 14 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2017 · Synced Oct 28, 2026, 9:08 PM EDT
Recruiting No phase listed Observational

Investigating Periprosthetic Fracture Cultures in Arthroplasty

NCT06952738
View directory record Official record
Conditions
Periprosthetic Fracture Around Prosthetic Joint Implant
Interventions
Not applicable- observational study
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation

NCT05205616
View directory record Official record
Conditions
Surgical Complication, Paresthesia, Fracture, Nerve Injury, Nerve Entrapments, Mandibular Nerve Injuries, Mandibular Hypoplasia, Mandibular Retrognathism, Mandibular Hyperplasia, Mandibular Prognathism
Interventions
Sonopet ultrasonic saw, Reciprocating saw
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
Up to 45 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Oct 28, 2026, 9:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Examining the Long-Term Risks of Oophorectomy

NCT00655447
View directory record Official record
Conditions
Coronary Heart Disease, Stroke, Breast Cancer, Ovarian Cancer, Cancer, Hip Fracture, Death
Interventions
Not listed
Lead sponsor
Parker, William H., M.D.
Other
Eligibility
30 Years to 55 Years · Female only
Enrollment
32,175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1980 – 2004
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2008 · Synced Oct 28, 2026, 9:08 PM EDT
Recruiting Not applicable Interventional

RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

NCT06455085
View directory record Official record
Conditions
Osteoporosis, Osteoporotic Fractures, Fragility Fracture
Interventions
Augmented-Fracture Liaison Service Arm, Enhanced Usual Care Arm
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years and older
Enrollment
2,634 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
23
States / cities
Birmingham, Alabama • Scottsdale, Arizona • North Little Rock, Arkansas + 19 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Phase 4 Interventional Results available

Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures

NCT02793947
View directory record Official record
Conditions
Pain, Postoperative, Femur Fracture
Interventions
Ropivacaine, Epinephrine, Morphine, 0.9% sodium chloride solution
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 28, 2026, 9:08 PM EDT
Recruiting Not applicable Interventional

Trial of Social Work Services in Fracture Clinic Setting

NCT06973655
View directory record Official record
Conditions
Orthopaedic Fractures, Socioeconomic Factors
Interventions
Social Work support
Other
Lead sponsor
Sheila Sprague
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 28, 2026, 9:08 PM EDT
Terminated Not applicable Interventional Results available

The Effect of Botulinum Toxin A Injections on Ankle Dorsiflexion Following Internal Fixation of Tibial Pilon Fractures

NCT02051933
View directory record Official record
Conditions
Equinus Contracture
Interventions
Botulinum toxin type A, sodium chloride
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Phase 4 Interventional Results available

VERtebral Fracture Treatment Comparisons in Osteoporotic Women

NCT01709110
View directory record Official record
Conditions
Postmenopausal Osteoporosis
Interventions
Teriparatide, Risedronate, Placebo, Calcium, Vitamin D
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
45 Years and older · Female only
Enrollment
1,366 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
30
States / cities
Birmingham, Alabama • Concord, California • Fresno, California + 27 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2019 · Synced Oct 28, 2026, 9:08 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Immobilization of Postoperative Distal Radius Fractures

NCT02802774
View directory record Official record
Conditions
Distal Radius Fractures
Interventions
Plaster Splint, Velcro Brace, Soft Dressing
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
2
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Oct 28, 2026, 9:08 PM EDT
Completed No phase listed Observational

Development and Validation of Intraoperative Image-quality Criteria

NCT01660490
View directory record Official record
Conditions
Proximal Femur Fractures
Interventions
ORIF
Procedure
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 19, 2014 · Synced Oct 28, 2026, 9:08 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

New Tools for Assessing Fracture Risk

NCT02436356
View directory record Official record
Conditions
Osteoporosis, Fracture Risk Assessment
Interventions
Osteoprobe-Reference Point Indentation (RPI), Dual-energy X-ray absorptiometry (DXA) Scans, MRI
Device · Radiation
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Oct 28, 2026, 9:08 PM EDT