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ClinicalTrials.gov public records Last synced Oct 24, 2026, 9:58 AM EDT

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Showing 145–168 of 917 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Fracture Clear all
Recruiting Phase 2 Interventional

Local Anesthesia for Facial Fractures

NCT06429501
View directory record Official record
Conditions
Pain Management
Interventions
Bupivacaine/Epinephrine, Saline
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 24, 2026, 9:58 AM EDT
Terminated Early Phase 1 Interventional

PVB vs Ketamine/Lidocaine in Rib Fracture Patients

NCT04413799
View directory record Official record
Conditions
Rib Fractures, Rib Trauma, Rib Fracture Multiple, Pain, Acute
Interventions
lidocaine, ketamine intravenous infusion, paravertebral block with ropivicaine
Combination Product · Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 22, 2025 · Synced Oct 24, 2026, 9:58 AM EDT
Withdrawn Phase 4 Interventional

The Effect of Tranexamic Acid on Transfusion Rates in Intertrochanteric Hip Fractures

NCT01940536
View directory record Official record
Conditions
Hip Fracture, Blood Loss
Interventions
Tranexamic Acid, Placebo
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 28, 2017 · Synced Oct 24, 2026, 9:58 AM EDT
Terminated Not applicable Interventional Results available

The Effect of Botulinum Toxin A Injections on Ankle Dorsiflexion Following Internal Fixation of Tibial Pilon Fractures

NCT02051933
View directory record Official record
Conditions
Equinus Contracture
Interventions
Botulinum toxin type A, sodium chloride
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Oct 24, 2026, 9:58 AM EDT
Completed Not applicable Interventional Results available

Fixation of Unstable Distal Radius Fractures

NCT00654615
View directory record Official record
Conditions
Distal Radius Fractures
Interventions
Intramedullary Radius Fixation (Micronail), Volar Plate Fixation
Device · Procedure
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Oct 24, 2026, 9:58 AM EDT
Completed Not applicable Interventional

Fibular Fixation in Ankle Fractures:Plate Verses Nail.

NCT02507193
View directory record Official record
Conditions
Distal Fibula Fracture
Interventions
Open reduction internal fixation, Intermedullary Nail
Procedure
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 24, 2026, 9:58 AM EDT
Recruiting Not applicable Interventional

Semiconductor Embedded Socks for Ankle Sprains

NCT07025733
View directory record Official record
Conditions
Ankle Sprain
Interventions
Semiconductor Embedded Sock, Control Compression Sock
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 24, 2026, 9:58 AM EDT
Completed No phase listed Observational

Treatment of Pediatric Mid-shaft Clavicle Fractures: A Prospective, Observational Study

NCT03402269
View directory record Official record
Conditions
Clavicle Fracture, Adolescent
Interventions
Clavicle fracture injury- observation
Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
11 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 28, 2023 · Synced Oct 24, 2026, 9:58 AM EDT
Completed Not applicable Interventional

The Use of RIA to Harvest Bone Graft for Treatment of Non-unions and Fractures

NCT00582439
View directory record Official record
Conditions
Orthopaedic Trauma Fractures and Non-unions
Interventions
Reamer-Irrigator-Aspirator (RIA)
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 1, 2013 · Synced Oct 24, 2026, 9:58 AM EDT
Completed Phase 3 Interventional Results available

Zoledronic Acid - Letrozole Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women With Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy

NCT00050011
View directory record Official record
Conditions
Breast Neoplasms, Osteoporosis
Interventions
Zoledronic Acid, Letrozole
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 85 Years · Female only
Enrollment
602 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2009
U.S. locations
43
States / cities
Springdale, Arkansas • Burbank, California • Lafayette, California + 39 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2014 · Synced Oct 24, 2026, 9:58 AM EDT
Recruiting Not applicable Interventional

Nutritional Supplementation in Geriatric Hip Fractures

NCT06773000
View directory record Official record
Conditions
Geriatric Hip Fracture
Interventions
XR™ Recovery Supplement, XR Carbohydrate Loading Supplement
Dietary Supplement
Lead sponsor
NYU Langone Health
Other
Eligibility
65 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 24, 2026, 9:58 AM EDT
Recruiting No phase listed Observational

The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma

NCT06606119
View directory record Official record
Conditions
Trauma Injury, Trauma, Critical Illness, Microbiome, Chronic Anemia, Acute Blood Loss Anemia
Interventions
Data and tissue collection
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 24, 2026, 9:58 AM EDT
Terminated Phase 4 Interventional

Local Application of Vancomycin Powder in Grade I-IIIA Open Fractures

NCT02400112
View directory record Official record
Conditions
Fractures, Open, Surgical Wound Infection
Interventions
Vancomycin
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Oct 24, 2026, 9:58 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Hip Fracture Exercise and Rehabilitation Post Hip Fracture Study

NCT03247205
View directory record Official record
Conditions
Hip Fractures, Cognitive Impairment
Interventions
HipERS
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
65 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Oct 24, 2026, 9:58 AM EDT
Recruiting Phase 4 Interventional

A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements

NCT07552766
View directory record Official record
Conditions
Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified, Fracture Elbow, Fracture Fixation, Fracture Fixation, Internal, Fracture Forearm, Fracture Distal Radius
Interventions
Lidocaine Infusion, Standard of Care (SOC)
Drug · Other
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
3 Years to 18 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 24, 2026, 9:58 AM EDT
Completed Phase 4 Interventional

FREE Study - Fracture Reduction Evaluation

NCT00211211
View directory record Official record
Conditions
Osteopenia, Osteoporosis, Multiple Myeloma, Bone Neoplasms
Interventions
Balloon Kyphoplasty
Device
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 8, 2017 · Synced Oct 24, 2026, 9:58 AM EDT
Not listed Phase 4 Interventional

The Use of Teriparatide as an Adjunctive Therapy for the Treatment of Jones Fractures

NCT01173081
View directory record Official record
Conditions
Fractures
Interventions
Teriparatide, Placebo
Drug
Lead sponsor
Ohio Orthopedic Center of Excellence
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Upper Arlington, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 5, 2012 · Synced Oct 24, 2026, 9:58 AM EDT
Active, not recruiting No phase listed Observational

Dupilumab Treatment Effects in an Ethnically Diverse Population With Chronic Rhinosinusitis With Nasal Polyposis

NCT05246267
View directory record Official record
Conditions
Chronic Rhinosinusitis With Nasal Polyps
Interventions
Dupilumab
Biological
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 24, 2026, 9:58 AM EDT
Completed Not applicable Interventional Results available

Treatment of Adult Traumatic Rib Fractures With Percutaneous Cryoneurolysis

NCT05330611
View directory record Official record
Conditions
Rib Fractures
Interventions
Cryoneurolysis of Intercostal Nerves, Standard of Care
Device · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 64 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 24, 2026, 9:58 AM EDT
Completed Phase 2 Interventional

Abaloparatide and Pelvic Fracture Healing

NCT04249232
View directory record Official record
Conditions
Fracture of Pelvis (Disorder)
Interventions
Abaloparatide 80 micrograms per Pen dose, Placebo prefilled injector pen
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
50 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
3
States / cities
New York, New York • Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Jun 14, 2024 · Synced Oct 24, 2026, 9:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Skeletal Health in Bariatric Surgery Patients

NCT03331536
View directory record Official record
Conditions
Bariatric Surgery, Osteoporosis, Fractures, Bone, Roux En-Y Gastric Bypass, Sleeve Gastrectomy, Menopause, Premenopause
Interventions
Roux en Y Gastric Bypass Pre-menopausal, Roux en Y Gastric Bypass Post-menopausal, Sleeve Gastrectomy Pre-menopausal, Sleeve Gastrectomy Post-menopausal
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older · Female only
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 18, 2020 · Synced Oct 24, 2026, 9:58 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Continuous Saphenous Nerve Block to Supplement a Continuous Sciatic Nerve Block After Ankle Surgery

NCT01167907
View directory record Official record
Conditions
Orthopedic Surgery of Lower Extremity
Interventions
0.2% ropivacaine, saline
Device · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 24, 2026, 9:58 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Retrograde Femoral Nail-Advanced Outcomes for Fixation of Distal Femur and Femoral Shaft Fractures

NCT05680987
View directory record Official record
Conditions
Femoral Fracture
Interventions
RFN-Advanced Retrograde Femoral Nailing System
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 24, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Fascia Iliaca Block in Hip Fracture Patients

NCT03525977
View directory record Official record
Conditions
Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures)
Interventions
Fascia iliaca block arm
Procedure
Lead sponsor
Texas Tech University Health Sciences Center, El Paso
Other
Eligibility
18 Years to 99 Years
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated May 28, 2019 · Synced Oct 24, 2026, 9:58 AM EDT