Independent directory Public ClinicalTrials.gov records United States
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Showing 1–24 of 1,808 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Human Cerebrovascular Function Using Acute Intermittent Hypoxia

NCT05164705
Conditions
Healthy Brain Perfusion
Interventions
Acute Intermittent Hypoxia, Sham Acute Intermittent Hypoxia
Other
Lead sponsor
Northwestern University
Other
Eligibility
21 Years to 50 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Myocardial Perfusion, Oxidative Metabolism, and Fibrosis in HFpEF

NCT02589977
Conditions
Heart Failure, Diastolic, Diastolic Heart Failure, Hypertension
Interventions
regadenoson
Drug
Lead sponsor
Marvin W. Kronenberg, M.D.
Other
Eligibility
50 Years to 75 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Completed Not applicable Interventional Accepts healthy volunteers

Lymphedema Progression Screening Using MRI

NCT02611557
Conditions
Lymphedema, Breast Cancer
Interventions
Manual lymphatic drainage therapy
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
2
States / cities
Nashville, Tennessee
Completed No phase listed Observational Accepts healthy volunteers

Relation of Consummatory & Anticipatory Food Reward to Obesity

NCT02084836
Conditions
Obesity
Interventions
Functional Magnetic Resonance Imaging
Other
Lead sponsor
Oregon Research Institute
Other
Eligibility
14 Years to 17 Years
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Eugene, Oregon
Completed Not applicable Interventional Results available

Oxytocin in Cocaine Dependence

NCT01573273
Conditions
Cocaine Dependence
Interventions
Oxytocin, Saline
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Brain Injuries, Acute, Brain Injuries, Traumatic, Brain Ischemia, Brain Hypoxia, Hypoxia-Ischemia, Brain, Heart Arrest, Stroke, Intracranial Hemorrhages, Coma, Persistent Vegetative State
Interventions
Phenobarbital Sodium Injection, Levetiracetam, Lacosamide Injectable Product, Valproate Sodium, Fosphenytoin
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Months to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Type 2 Diabetes Mellitus
Interventions
Exenatide, Glipizide
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
30 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Houston, Texas
Conditions
Alzheimer Disease
Interventions
Intermittent theta burst stimulation
Device
Lead sponsor
HealthPartners Institute
Other
Eligibility
40 Years to 90 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Saint Paul, Minnesota
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Brain Blood Flow Responses During Exercise: Younger Cohort

NCT06446622
Conditions
Cerebrovascular Circulation, Magnetic Resonance Imaging
Interventions
MRI
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
20 Years to 40 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Social Anhedonia, Social Function Impairment
Interventions
Behavioral Activation (BA), Supportive Care Therapy (SCT)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
San Diego, California
Completed No phase listed Observational Accepts healthy volunteers

Early MRI Prediction of Crohns

NCT03340519
Conditions
Crohn Disease
Interventions
MR Imaging
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
11 Years to 25 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
IgA Nephropathy (IgAN), Immunoglobulin A Nephropathy (IgAN)
Interventions
atrasentan
Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Neural Correlates of Lidocaine Analgesia

NCT05501600
Conditions
Anesthesia, Pain
Interventions
Peripheral Nerve Stimulation, Lidocaine IV
Device · Drug
Lead sponsor
Keith M Vogt
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Terminated No phase listed Observational Accepts healthy volunteers

Linking Cognitive Functioning to Multimodal Imaging in Multiple Sclerosis (MS)

NCT03723356
Conditions
Multiple Sclerosis, Cognition Disorders
Interventions
Siemens Biograph mMR (molecular MR), fMRI, Diffusion Spectrum Imaging (DSI)
Diagnostic Test
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 45 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Conditions
Cerebral Palsy, Typically Developing Children
Interventions
MRI, HD-EEG Recording, rTMS
Device
Lead sponsor
Cook Children's Health Care System
Other
Eligibility
6 Years to 20 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Depression in Adolescence, Rumination
Interventions
Mindfulness + fMRI Neurofeedback
Other
Lead sponsor
Columbia University
Other
Eligibility
13 Years to 18 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Youth Soccer Header Study

NCT04919707
Conditions
Brain Injuries
Interventions
Header Session, MRI Session
Behavioral · Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
12 Years to 18 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Madison, Wisconsin
Completed No phase listed Observational Accepts healthy volunteers

FMRI of Stress and Addictive Disorders

NCT01558973
Conditions
Cocaine Dependence, Opioid Dependence, Alcoholism, Pathological Gamblers, Adolescents
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
13 Years to 50 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2005
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Mental Function
Interventions
Propofol for fMRI, Dexmedetomidine for fMRI, Dorsolateral prefrontal cortex (DLPFC) pulsation, Anterior insular cortex (AIC) pulsation, Central thalamus (CT) pulsation
Procedure · Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 40 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Accepts healthy volunteers

Choline Dose Ranging in Postmenopausal Women

NCT06924541
Conditions
Menopause
Interventions
Choline, Placebo
Dietary Supplement
Lead sponsor
Julie Dumas
Other
Eligibility
50 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Burlington, Vermont
Conditions
Chronic Back Pain, Chronic Pain (Back / Neck)
Interventions
low intensity focused ultrasound (LIFU)
Device
Lead sponsor
Washington D.C. Veterans Affairs Medical Center
Federal
Eligibility
21 Years to 75 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Alcohol Use Disorder
Interventions
Suvorexant, Placebo
Drug · Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Phenytoin as a Neuroprotective Agent Against Corticosteroid-induced Functional Imaging Changes

NCT00591006
Conditions
Healthy
Interventions
Phenytoin (brand name Dilantin), Hydrocortisone, Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Dallas, Texas
Active, not recruiting Not applicable Interventional

Compressed Intermittent Theta Burst Stimulation

NCT04684706
Conditions
Treatment Resistant Depression
Interventions
intermittent Theta Burst Stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
2
States / cities
La Jolla, California • Philadelphia, Pennsylvania