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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Functional neuromuscular electrical stimulation Clear all
Completed Not applicable Interventional

Knee Arthroplasty Rehabilitation Outcomes Study

NCT02426190
View directory record Official record
Conditions
Total Knee Arthroplasty, Rehabilitation
Interventions
Anti-gravity treadmill, PENS - neuro-muscular stimulation, Anti-gravity treadmill & PENS - neuro-muscular stimulation, Recumbent or Nu-step bike
Other
Lead sponsor
MedStar National Rehabilitation Network
Other
Eligibility
40 Years and older
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Sep 29, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Short Term Immobilization of the Lower Limb

NCT05072652
View directory record Official record
Conditions
Weakness, Muscle, Muscle Weakness, Muscle Loss, Muscle Atrophy, Injury, Knee
Interventions
Neuromuscular Electrical Stimulation, Action Observation + Mental Imagery
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Sep 29, 2026, 1:27 AM EDT
Not listed Phase 1 Interventional

Electrical Stimulation After Total Knee Arthroplasty

NCT00224913
View directory record Official record
Conditions
Total Knee Arthroplasty, Osteoarthritis
Interventions
Neuromuscular electrical stimulation, Voluntary exercise
Procedure
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
45 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Oct 11, 2005 · Synced Sep 29, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Neuromuscular Electrical Stimulation (NMES) for Improving Outcomes Following Total Knee Arthroplasty (TKA)

NCT03044028
View directory record Official record
Conditions
Arthropathy of Knee Joint
Interventions
CyMedica Orthopedics QB1 e-vive™ system
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Sep 29, 2026, 1:27 AM EDT
Not yet recruiting Not applicable Interventional

Determining the Effects of Ischemic Conditioning and Neuromuscular Electrical Stimulation on Overall Function After Lower Limb Amputation

NCT07664995
View directory record Official record
Conditions
Lower Limb Amputation Above Knee, Below Knee Amputation
Interventions
Blood pressure cuff, Neuromuscular Electrical Stimulation
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 29, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Detecting Change in Muscle Parameters, Pain, and Function With NMES for TTA

NCT06830876
View directory record Official record
Conditions
Amputation
Interventions
Chattanooga Continuum Device
Device
Lead sponsor
Sara Peterson-Snyder
Industry
Eligibility
18 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 16, 2025 · Synced Sep 29, 2026, 1:27 AM EDT
Terminated Not applicable Interventional Results available

Impact of the Erigo Machine on Functional Recovery in ICU Patients

NCT02615990
View directory record Official record
Conditions
Trauma Patients Requiring Physical Rehabilitation
Interventions
Erigo Pro, Standard Physical Therapy
Device · Other
Lead sponsor
Lisa J. Fryman
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 24, 2018 · Synced Sep 29, 2026, 1:27 AM EDT
Not listed Not applicable Interventional

Facilitating Functional Independence in Patients Receiving Prolonged Mechanical Ventilation

NCT02847988
View directory record Official record
Conditions
Muscle Weakness
Interventions
Neuromuscular electrical Stimulation (NMES), Sham Stimulation
Device
Lead sponsor
RML Specialty Hospital
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Hinsdale, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Sep 29, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Electrical Stimulation for Recovery of Hand Function in Chronic Stroke Survivors

NCT00891319
View directory record Official record
Conditions
Stroke, Hemiparesis, Hemiplegia
Interventions
Electrical stimulator
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 29, 2026, 1:27 AM EDT
Terminated Not applicable Interventional

NMES to Improve Eyelid Functions in Cranial Nerve (CN) III and VII Palsy

NCT03239418
View directory record Official record
Conditions
Blepharoptosis, Lagophthalmos
Interventions
Neuromuscular electrical stimulation, Sham neuromuscular electrical stimulation
Device
Lead sponsor
Brooks Rehabilitation
Other
Eligibility
19 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 20, 2022 · Synced Sep 29, 2026, 1:27 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Premature Fatigue in Veterans With Heart Failure: Neuronal Influences

NCT02209610
View directory record Official record
Conditions
Heart Failure
Interventions
Electrical and Magnetic Nerve Stimulators, Intrathecal Fentanyl
Device · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Sep 29, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Alternative Exercise Program to Improve Skeletal Muscle Function and Fatigue in Cancer Survivors

NCT02739620
View directory record Official record
Conditions
Breast Cancer
Interventions
Neuromuscular electrical stimulation
Device
Lead sponsor
University of Vermont
Other
Eligibility
40 Years to 70 Years · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Sep 29, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Muscle Stimulation for Physical Function During Stem Cell Transplant

NCT04364256
View directory record Official record
Conditions
Autologous Hematopoietic Stem Cell Transplant
Interventions
RS-4i Plus Sequential Stimulator (RS Medical, Vancouver, WA)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 1, 2026 · Synced Sep 29, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Pivotal Evaluation of Abdominal Neuromuscular Electrical Stimulation (VentFree) for Weaning From Mechanical Ventilation

NCT05759013
View directory record Official record
Conditions
Respiration, Artificial, Ventilators, Mechanical
Interventions
Breath synchronized abdominal FES, Sham breath synchronized abdominal FES
Device
Lead sponsor
Liberate Medical
Industry
Eligibility
22 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
15
States / cities
Long Beach, California • Jacksonville, Florida • Hines, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 29, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Metabolic Health in Individuals With Spinal Cord Injury (SCI)

NCT03204240
View directory record Official record
Conditions
Spinal Cord Injuries, Skeletal Muscle Atrophy, Metabolic Disease
Interventions
Neuromuscular electrical stimulation
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 26, 2023 · Synced Sep 29, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Electrical Stimulation to Strengthen Muscles in the Lower Legs in Patients Requiring Prolonged Mechanical Ventilation

NCT01825135
View directory record Official record
Conditions
Muscle Weakness
Interventions
Neuromuscular electrical stimulation, sham stimulation
Device
Lead sponsor
RML Specialty Hospital
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Hinsdale, Illinois
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Sep 29, 2026, 1:27 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effect of Neuromuscular Electrical Stimulation on the Post-Operative Abdominoplasty Patient.

NCT05229692
View directory record Official record
Conditions
Rectus Diastasis
Interventions
NEUBIE
Device
Lead sponsor
NeuFit - Neurological Fitness and Education
Industry
Eligibility
18 Years to 65 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 8, 2023 · Synced Sep 29, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques

NCT07112404
View directory record Official record
Conditions
Pain, Back Pain, Lower Back Pain, Quality of Life
Interventions
Dry Needling, Dry needling with high-rate PENS, Dry needling with low-rate PENS
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 29, 2026, 1:27 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Ultrasound Imaging Based Sensing of Human Ankle Motion Intent and Control Strategies for Ankle Assistance

NCT05249595
View directory record Official record
Conditions
Incomplete Spinal Cord Injury, Transverse Myelitis
Interventions
Surface electromypgraphy-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Surface electromypgraphy and ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices
Device
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 64 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 20, 2022 · Synced Sep 29, 2026, 1:27 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

VentFree: A Novel Abdominal Stimulator to Assist With Ventilator Weaning

NCT02224352
View directory record Official record
Conditions
COPD, Weaning Failure
Interventions
Functional neuromuscular electrical stimulation
Device
Lead sponsor
Edward Hines Jr. VA Hospital
Federal
Eligibility
18 Years to 90 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
2
States / cities
Hines, Illinois • Hinsdale, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 16, 2021 · Synced Sep 29, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional

Effect of NMES on Balance and Fall Risk in Chronic Stroke

NCT04957355
View directory record Official record
Conditions
Chronic Stroke
Interventions
Neuromuscular electrical stimulation (NMES) or Functional electrical stimulation (FES)
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 29, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of NMES Therapy for Pain Relief Associated With Knee Osteoarthritis

NCT04367597
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Home-based Neuromuscular Electrical Stimulation (NMES) therapy
Device
Lead sponsor
CyMedica Orthopedics, Inc
Industry
Eligibility
21 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
5
States / cities
Tucson, Arizona • Houston, Texas • Katy, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Sep 29, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional

Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty

NCT06953375
View directory record Official record
Conditions
Total Knee Arthroplasty, Functional Recovery, Aging, Physical Therapy
Interventions
NMES, Usual Care
Procedure · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
3,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
3
States / cities
Aurora, Colorado • Murray, Utah
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 29, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brain and Coordination Changes Induced By Robotics and FES Treatment Following Stroke

NCT00237744
View directory record Official record
Conditions
Cerebral Stroke, Cerebrovascular Accident, Stroke
Interventions
Robotics training for shoulder elbow., Surface Functional Neuromuscular Stimulation, whole arm motor learning
Device · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 12, 2014 · Synced Sep 29, 2026, 1:27 AM EDT