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Showing 169–192 of 706 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Results available

Thymus Transplantation Safety-Efficacy

NCT01220531
Conditions
Complete DiGeorge Anomaly, DiGeorge Syndrome, DiGeorge Anomaly, Complete DiGeorge Syndrome
Interventions
Cultured Thymus Tissue
Biological
Lead sponsor
Sumitomo Pharma Switzerland GmbH
Industry
Eligibility
Not listed
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Pediatric Femur Fracture
Interventions
Functional Brace, Hip Spica Cast
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
Up to 5 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
2
States / cities
Los Angeles, California • Aurora, Colorado
Terminated No phase listed Observational Results available

Brain Networks and Consciousness

NCT04502550
Conditions
Loss of Consciousness, Parkinson Disease, Essential Tremor, Anesthesia
Interventions
Propofol
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Brain Activity Related to Opioid Administration, Brain Activity Related to Drug Liking
Interventions
Observational study in patients receiving fentanyl for surgery
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Spine Fusion, Spine Tumor, Spinal Stenosis
Interventions
Ketamine
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Francisco, California
Conditions
Heart Diseases
Interventions
Dexmedetomidine buccal, Dexmedetomidine Intranasal
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Months to 48 Months
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Glioblastoma
Interventions
Awake mapping under local anesthesia, Asleep mapping under general anesthesia, Resection under general anesthesia without mapping
Procedure
Lead sponsor
Erasmus Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
453 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
San Francisco, California • Boston, Massachusetts
Conditions
Anesthesia, Surgery
Interventions
I-Gel Laryngeal Mask Airway, Ambu Auragain Laryngeal Mask Airway
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 80 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Depressive Disorder, Major, Depressive Disorder, Treatment-Resistant
Interventions
Nitrous Oxide, Placebo gas, MRI
Drug · Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Withdrawn Not applicable Interventional Accepts healthy volunteers

Use of Virtual Reality for Pediatric Minor Surgical Procedures

NCT04125004
Conditions
Virtual Reality, General Anesthesia
Interventions
Samsung Virtual Reality Headset
Device
Lead sponsor
Stanford University
Other
Eligibility
7 Years to 18 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Hepatic Encephalopathy, Liver Cirrhosis, Portal Shunt Systemic
Interventions
Endoscopic ultrasound-guided transgastric embolization of the spontaneous portosystemic shunts, Interventional Radiology for shunt embolization/retrograde tranvenous obliteration
Procedure
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Newark, New Jersey
Completed No phase listed Observational Accepts healthy volunteers

Anxiety Level Assessment of Anesthesia Providers During COVID-19 Pandemic

NCT05212909
Conditions
Anxiety
Interventions
General Anxiety Disorder-7 scale
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
Not listed
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Reversible Pulpitis, Caries
Interventions
Formocresol application after pulpotomy preparation, GENTLEray 980 Soft Tissue diode laser
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
3 Years to 8 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Cystoscopes, Baxter Anaesthesia Brand of Desflurane, Sevoflurane
Interventions
Desflurane, Sevoflurane
Drug
Lead sponsor
Ohio State University
Other
Eligibility
50 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Neuromuscular Blockade
Interventions
Sugammadex 2 mg/kg ABW, Sugammadex 2 mg/kg IBW, Sugammadex 4 mg/kg ABW, Sugammadex 4 mg/kg IBW, Neostigmine + Glycopyrrolate, Rocuronium or Vecuronium
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years and older
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
13
States / cities
Sacramento, California • Miami, Florida • Kansas City, Kansas + 9 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Local Anesthetics

NCT01402869
Conditions
Methemoglobinemia
Interventions
4% prilocaine plain, 2% Lidocaine with 1:100,000 epinephrine
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
3 Years to 5 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Loma Linda, California
Conditions
Atrial Fibrillation
Interventions
General Anesthesia with endotracheal tube, General Anesthesia with laryngeal mask airway
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Retinoblastoma, Retinal Neoplasm
Interventions
Enucleation, Vincristine, Carboplatin, Focal Therapies, External Beam Radiation, Vincristine and Topotecan, Vincristine + Carboplatin + Etoposide, vincristine, cyclophosphamide, and doxorubicin, Vincristine, Carboplatin and Etoposide, Periocular carboplatin, G-CSF
Procedure · Drug · Radiation + 1 more
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Not listed
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Colon Cancer
Interventions
Regional anesthesia and analgesia, general anesthesia followed by opioid analgesia
Procedure · Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Malignant Neoplasms of Respiratory and Intrathoracic Organs, Lung Neoplasm
Interventions
Bronchoscopy, Radial Probe Endobronchial Ultrasound
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Houston, Texas
Conditions
Total Knee Arthroplasty
Interventions
Active Noise Cancelling Headset System
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Hip Fractures, Anesthesia, Delirium
Interventions
cerebral oximeter (Fore-Sight), depth of anesthesia monitor (BIS), BP management, General anesthesia, propofol, fentanyl, sevoflurane
Device · Procedure · Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
65 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Mental Retardation
Interventions
BIS monitor
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
12 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Newark, New Jersey
Recruiting No phase listed Observational Accepts healthy volunteers

Timing of Opioid Administration and Postoperative Respiratory Depression.

NCT07227389
Conditions
Respiratory Complications, Opioid Induced Respiratory Depression, Postoperative Respiratory Complications
Interventions
Respiratory volume monitoring
Diagnostic Test
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 85 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Detroit, Michigan