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ClinicalTrials.gov public records Last synced Sep 12, 2026, 10:42 AM EDT

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Showing 1–24 of 25 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Goal-directed Therapeutic Protocol Clear all
Not yet recruiting Not applicable Interventional

Clinical and Neurocomputational Effects of Behavioral Activation in Veterans With Impaired Social Functioning

NCT07697001
View directory record Official record
Conditions
Social Anhedonia, Social Function Impairment
Interventions
Behavioral Activation (BA), Supportive Care Therapy (SCT)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 12, 2026, 10:42 AM EDT
Withdrawn Phase 4 Interventional

Adaptive Response to Intervention (RTI) for Students With ADHD

NCT03511976
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity
Interventions
Tier 1 Classroom Management, Daily Report Card (DRC), Enhanced DRC (DRC-E), Stimulant
Behavioral · Drug
Lead sponsor
Florida International University
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Miami, Florida • Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 12, 2026, 10:42 AM EDT
Recruiting Not applicable Interventional

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

NCT05934487
View directory record Official record
Conditions
Heart Failure NYHA Class II, Heart Failure NYHA Class III, Heart Failure
Interventions
Cordella™ Pulmonary Artery Sensor System
Device
Lead sponsor
Endotronix, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2033
U.S. locations
45
States / cities
Phoenix, Arizona • Los Angeles, California • San Francisco, California + 35 more
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 12, 2026, 10:42 AM EDT
Completed Not applicable Interventional

Echo vs. EGDT in Severe Sepsis and Septic Shock

NCT02354742
View directory record Official record
Conditions
Severe Sepsis, Septic Shock
Interventions
Echo guided fluid resuscitation, EGDT fluid resuscitation
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Jul 15, 2018 · Synced Sep 12, 2026, 10:42 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Hybrid Effectiveness-Implementation Trial of an Executive Functioning Intervention for Children's Mental Health Services

NCT06651086
View directory record Official record
Conditions
Autism Spectrum Disorder, Executive Functioning
Interventions
Unstuck and On Target, Unified Protocol for Children
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
6 Years to 99 Years
Enrollment
672 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
2
States / cities
San Diego, California • Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 12, 2026, 10:42 AM EDT
Completed Not applicable Interventional

Home Exercise Telerehabiliation for MS

NCT03655431
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Telerehabilitation, Standard treatment
Other
Lead sponsor
Shane.Chanpimol
Federal
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Sep 12, 2026, 10:42 AM EDT
Completed Not applicable Interventional Results available

Selecting Effective Combinations of Treatment for Low Back Pain

NCT03520387
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar medial branch nerve radiofrequency ablation (LRFA), Simulated LRFA with targeted steroid injections, AcTIVE-CBT, TBSCE
Procedure · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Sep 12, 2026, 10:42 AM EDT
Active, not recruiting Not applicable Interventional

Behavioral Economic and Wellness-based Approaches for Reducing Alcohol Use and Consequences Among Emerging Adults

NCT04776278
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Brief Alcohol Intervention (BAI), Substance-free Activity Session (SFAS), Relaxation Training (RT), Education Control
Behavioral · Other
Lead sponsor
University of Memphis
Other
Eligibility
18 Years to 29 Years
Enrollment
525 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Sep 12, 2026, 10:42 AM EDT
Recruiting Not applicable Interventional

Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode

NCT05890183
View directory record Official record
Conditions
Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder
Interventions
Cognitive training, Aerobic Exercise Program, Moderated Online Social Therapy (MOST), Chorus Participatory Text Messaging Program, Healthy Living Group (HLG)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 45 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 12, 2026, 10:42 AM EDT
Completed Not applicable Interventional

Reducing Distress and Improving Self-Care in Diabetes

NCT00714441
View directory record Official record
Conditions
Diabetes Type 2
Interventions
Lifestyle and Activities Education Program (LEAP-AHEAD), Computer Automated Self-Management (CASM), Computer Automated Self-Management and Problem Solving Therapy (CAPS)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 75 Years
Enrollment
392 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2012 · Synced Sep 12, 2026, 10:42 AM EDT
Terminated Phase 4 Interventional Results available

Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock

NCT00535821
View directory record Official record
Conditions
Severe Sepsis, Septic Shock
Interventions
Esophageal Doppler monitoring - CardioQ, Deltex Inc, Central line with CVP and continuous ScvO2 monitoring
Device
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
4
States / cities
Loma Linda, California • Worcester, Massachusetts • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 24, 2014 · Synced Sep 12, 2026, 10:42 AM EDT
Completed Not applicable Interventional Results available

Feasibility and Effect of a Strategy-Based Cognitive Intervention for Parkinson Disease

NCT04048122
View directory record Official record
Conditions
Parkinson Disease
Interventions
MultiContext for PD Strategy Training, Standard of Care
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Sep 12, 2026, 10:42 AM EDT
Terminated Not applicable Interventional Results available

The Benefits of a Preoperative Anemia Management Program

NCT01888003
View directory record Official record
Conditions
Anemia, Iron-Deficiency
Interventions
Iron sucrose, Epoetin Alfa, Blood Transfusion
Drug · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 80 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Sep 12, 2026, 10:42 AM EDT
Recruiting No phase listed Observational

Active Surveillance in Older Women With ER+ Breast Cancer

NCT07262138
View directory record Official record
Conditions
Early Stage Estrogen Receptor (ER) Positive Breast Cancer
Interventions
Active Surveillance
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
70 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 12, 2026, 10:42 AM EDT
Completed Phase 2 Interventional Results available

Hemodynamics and Extravascular Lung Water in Acute Lung Injury

NCT00624650
View directory record Official record
Conditions
Acute Lung Injury
Interventions
Diuresis (furosemide) part I, Fluid Bolus (crystalloid or albumin), Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine), Dobutamine, Concentrate all drips and nutrition, Diuresis (furosemide) part II, Dialysis
Drug · Other · Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
3
States / cities
Clackamas, Oregon • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Sep 12, 2026, 10:42 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Enhanced Recovery Pathway for Endoscopy

NCT04983498
View directory record Official record
Conditions
Enhanced Recovery Pathway, Endoscopy
Interventions
Ondansetron 4 MG, Lactated Ringers, Intravenous, Early Mobilization, Early PO Intake
Drug · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Sep 12, 2026, 10:42 AM EDT
Completed Phase 2 Interventional Results available

Robotic Assisted Upper-Limb Neurorehabilitation in Stroke Patients

NCT00372411
View directory record Official record
Conditions
Stroke
Interventions
Robot-Assisted Therapy - MIT-MANUS System, Intensive Comparison Therapy, Usual Care
Device · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
5
States / cities
West Haven, Connecticut • Gainesville, Florida • Baltimore, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2014 · Synced Sep 12, 2026, 10:42 AM EDT
Withdrawn Not applicable Interventional

Breast Reconstruction Following Breast Cancer in Very High Risk Patients

NCT03261323
View directory record Official record
Conditions
Breast Cancer, Malignant Neoplasm of Breast
Interventions
Immediate Breast Reconstruction, Delayed Breast Reconstruction, Breast-Q questionnaire
Procedure · Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
19 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Sep 12, 2026, 10:42 AM EDT
Completed Phase 1 Interventional

Ketogenic Diet in Combination With Standard-of-care Radiation and Temozolomide for Patients With Glioblastoma

NCT03451799
View directory record Official record
Conditions
GBM, Glioblastoma
Interventions
Ketogenic Diet, Standard-of-care radiation, Standard-of-care Temozolomide
Other · Radiation · Drug
Lead sponsor
Jethro Hu
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 12, 2026, 10:42 AM EDT
Completed No phase listed Observational

Evaluation of Intravenous Fluid Therapy Within Dallas Acute Pancreatitis Protocol

NCT06223594
View directory record Official record
Conditions
Acute Pancreatitis
Interventions
Intravenous Fluid Therapy
Other
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years to 75 Years
Enrollment
500 participants
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Sep 12, 2026, 10:42 AM EDT
Terminated Not applicable Interventional

Goal-directed Resuscitative Interventions During Pediatric Inter-facility Transport (The GRIPIT Trial)

NCT01293500
View directory record Official record
Conditions
Systemic Inflammatory Response Syndrome
Interventions
Goal-directed Therapeutic Protocol
Procedure
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
1 Month to 17 Years
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Sep 12, 2026, 10:42 AM EDT
Enrolling by invitation Early Phase 1 Interventional

Drug Screening of Cutaneous Lesions of Squamous Cell Carcinoma

NCT06782399
View directory record Official record
Conditions
Squamous Cell Carcinoma of the Skin, Squamous Cell Carcinoma
Interventions
Microdevice
Combination Product
Lead sponsor
Oliver Jonas
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 12, 2026, 10:42 AM EDT
Completed Not applicable Interventional

Telehealth Pilot for Veterans with Chronic Multi-Symptom Illness.

NCT04164667
View directory record Official record
Conditions
Chronic Multisymptom Illness
Interventions
Mental and physical (MAP) training intervention
Behavioral
Lead sponsor
War Related Illness and Injury Study Center
Federal
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 3, 2024 · Synced Sep 12, 2026, 10:42 AM EDT
Completed Not applicable Interventional

Enhanced Medical Rehabilitation for Spinal Cord Injury

NCT03952416
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Enhanced Medical Rehabilitation (EMR)
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 4, 2024 · Synced Sep 12, 2026, 10:42 AM EDT