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Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Results available

Spectacles for Patients With Down Syndrome

NCT03367793
View directory record Official record
Conditions
Vision, Low
Interventions
Spectacles - Clinically Derived, Spectacles - Metric Technique #1 Derived, Spectacles - Metric Technique #2 Derived
Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2021 · Synced Sep 4, 2026, 10:04 PM EDT
Completed No phase listed Observational Results available

Mental Imagery Therapy for Autism (MITA) - an Early Intervention Computerized Language Training Program for Children With ASD

NCT02708290
View directory record Official record
Conditions
Autistic Disorder, Autism, ASD
Interventions
MITA Prefrontal Synthesis exercises - each activity adapts to deliver the exercise that is at the exact level of difficulty appropriate for a child at any given point in time
Other
Lead sponsor
ImagiRation, LLC
Industry
Eligibility
2 Years to 12 Years
Enrollment
6,454 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 26, 2020 · Synced Sep 4, 2026, 10:04 PM EDT
Completed Phase 2 Interventional Results available

HSCT for High Risk Inherited Inborn Errors

NCT00383448
View directory record Official record
Conditions
Adrenoleukodystrophy, Metachromatic Leukodystrophy, Globoid Cell Leukodystrophy, Tay Sachs Disease, Sandhoffs Disease, Wolman Disease, I-Cell Disease, Sanfilippo Syndrome, GM1 Gangliosidosis
Interventions
Clofarabine, Total body Irradiation, Melphalan, Hematopoietic Stem Cell Transplantation, Alemtuzumab, mycophenylate mofetil, Cyclosporine A, Hydroxyurea
Drug · Procedure · Biological + 1 more
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
Up to 70 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Sep 4, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Studying the Effects of Natural Visual Scene Changes on Typical Adult Visual Perception

NCT05004649
View directory record Official record
Conditions
Visual Perception
Interventions
Psychophysical task
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Sep 4, 2026, 10:04 PM EDT
Completed Not applicable Interventional

A Comparison: High Intense Periodic vs. Every Week Therapy in Children With Cerebral Palsy (ACHIEVE)

NCT02897024
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Physical Therapy
Other
Lead sponsor
Ohio State University
Other
Eligibility
2 Years to 8 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 23, 2021 · Synced Sep 4, 2026, 10:04 PM EDT
Recruiting No phase listed Observational

Long-term Follow-up (LTFU) Study of Participants in Any iECURE Protocol Using an Investigational Product (IP)

NCT06805695
View directory record Official record
Conditions
Ornithine Transcarbamylase Deficiency, Ornithine Transcarbamylase Deficiency Disease, Urea Cycle Disorders, Inborn
Interventions
No Intervention
Other
Lead sponsor
iECURE, Inc.
Industry
Eligibility
7 Months to 15 Months
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2041
U.S. locations
2
States / cities
Aurora, Colorado • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 4, 2026, 10:04 PM EDT
Terminated Phase 3 Interventional Results available

Efficacy and Safety of SYNB1934 in Patients With PKU (SYNPHENY-3)

NCT05764239
View directory record Official record
Conditions
Phenylketonuria
Interventions
SYNB1934v1, Placebo
Drug
Lead sponsor
Synlogic
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
14
States / cities
Culver City, California • Orange, California • Palo Alto, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2024 · Synced Sep 4, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alternative Dietary Approaches Online to Promote Tracking

NCT05049005
View directory record Official record
Conditions
Diet Quality, Weight Loss
Interventions
Simplified dietary tracking
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 11, 2022 · Synced Sep 4, 2026, 10:04 PM EDT
Recruiting Phase 1Phase 2 Interventional

A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia

NCT06525636
View directory record Official record
Conditions
X-linked Hypophosphatemia
Interventions
KK8123
Drug
Lead sponsor
Kyowa Kirin Co., Ltd.
Industry
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
5
States / cities
San Francisco, California • New Haven, Connecticut • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 4, 2026, 10:04 PM EDT
Completed Not applicable Interventional

Prospective Randomized Trial of Streamlined Genetic Education and Testing for Ovarian Cancer Patients

NCT04537702
View directory record Official record
Conditions
Ovarian Cancer, Epithelial, Peritoneal Cancer, Fallopian Tube Cancer
Interventions
Streamlined Education, Traditional Education
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Sep 4, 2026, 10:04 PM EDT
Terminated Phase 1Phase 2 Interventional

A Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of mRNA-3705 in Participants With Isolated Methylmalonic Acidemia

NCT04899310
View directory record Official record
Conditions
Methylmalonic Acidemia
Interventions
mRNA-3705, Placebo
Biological
Lead sponsor
ModernaTX, Inc.
Industry
Eligibility
1 Year and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
Los Angeles, California • Palo Alto, California • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 4, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Teamwork for Neonatal Resuscitation

NCT00651794
View directory record Official record
Conditions
Teamwork During Neonatal Resuscitation
Interventions
Teamwork training, Standard NRP curriculum, Skills practice with low-fidelity mannequin, Skills practice with high-fidelity mannequin
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Sep 4, 2026, 10:04 PM EDT
Not listed No phase listed Observational

Evaluation of High-Performance, Customized, Rapidly-Manufacturable Prosthetic Feet That Provide Improved Mobility

NCT05265403
View directory record Official record
Conditions
Amputation of Lower Limb Below Knee
Interventions
Commercially-available energy storage and return prosthetic foot, MIT-Lower Leg Trajectory Error (LLTE) customized prosthetic feet
Drug · Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Sep 4, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Agitation in People With Dementia: the Customized Activity Trial

NCT01892579
View directory record Official record
Conditions
Dementia
Interventions
Tailored Activity Program, Home Safety and Education Program
Behavioral · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 22, 2019 · Synced Sep 4, 2026, 10:04 PM EDT
Completed Not applicable Interventional Results available

Vidatalk Communication Application: Usability, Acceptability and Efficacy Study

NCT02921776
View directory record Official record
Conditions
Nonverbal Communication, Critical Illness
Interventions
Aim 1 - VidaTalk - post-extubation, Aim 2 - VidaTalk - intubated, Aim 3 - VidaTalk tablet app, Aim 3 - attention-control with non-VidaTalk tablet
Other · Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 99 Years
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2022 · Synced Sep 4, 2026, 10:04 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke

NCT06458153
View directory record Official record
Conditions
Stroke, Cerebellum
Interventions
Neural responses to speech functional localizer, Neural responses to silent articulation, Neural responses to self vs. externally generated speech, Event-related potentials for speech, Neural responses to induced speech errors, Neural responses to sensory-motor adaptation, Speech production behaviors, Auditory acuity testing, Neural responses to learning a non-speech auditory motor behavior
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 4, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cortisol and Food Insecurity

NCT05191030
View directory record Official record
Conditions
Food Insecurity
Interventions
High-Stress Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
453 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 4, 2026, 10:04 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Human-like Robotic Controllers for Enhanced Motor Learning

NCT04578665
View directory record Official record
Conditions
Stroke, Spinal Cord Injuries
Interventions
Behavioral Interaction Conditions, Haptic Impedance Level, Skill Level of Partner, Robot Controller Showcase
Behavioral · Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
764 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 4, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Auditory-Perceptual Training Via Telepractice

NCT04858035
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Perceptual training, Production training
Behavioral
Lead sponsor
Montclair State University
Other
Eligibility
9 Years to 15 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Upper Montclair, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Sep 4, 2026, 10:04 PM EDT
Completed Not applicable Interventional

A Novel Optical Spectral Imaging System for Imaging Breast Tumor Margins

NCT01372631
View directory record Official record
Conditions
Breast Cancer
Interventions
miniature spectral imaging system, Bench-top optical spectrometer, High resolution microendoscope
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
2
States / cities
Durham, North Carolina • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Sep 4, 2026, 10:04 PM EDT
Recruiting Not applicable Interventional

Using Non-invasive Brain Stimulation to Explore Potential Treatments to Reduce Speech Errors in Adults Who Stutter

NCT07354139
View directory record Official record
Conditions
Stuttering, Fluency Disorder
Interventions
High - Definition Transcranial Direct Current Stimulation
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 4, 2026, 10:04 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Pre-malignant States to Hematologic Malignancies in Firefighters

NCT06870760
View directory record Official record
Conditions
Clonal Hematopoiesis of Indeterminate Potential, Monoclonal Gammopathy, Non Hodgkin Lymphoma, Leukemia, Multiple Myeloma, Plasma Cell Disorder
Interventions
Monoclonal Gammopathy, Complete Blood Count with differential (CBC w/ diff), Clonal hematopoiesis (CHIP)
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years to 49 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 4, 2026, 10:04 PM EDT
Completed Not applicable Interventional Results available

Effect of Gain on Closed-Loop Insulin

NCT02065895
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
HIGH error, NO error, LOW error
Device
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 16, 2018 · Synced Sep 4, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Video Communication Assessment for Teaching Error Disclosure Skills

NCT06234085
View directory record Official record
Conditions
Error Disclosure
Interventions
VCA feedback report available
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
7
States / cities
Boise, Idaho • Worcester, Massachusetts • Dearborn, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2024 · Synced Sep 4, 2026, 10:04 PM EDT